Critical Care / Medicine Flashcards
How do you estimate blood volume?
60cc / kg
Blood volume is approximately half of body weight in a normal adult
Classification for blood loss
Class I - EBL <750, BP and P and UOP nl
Class II - EBL 750-1500, UOP decreased, HR elevated, BP nl
Class III - EBL >1500, BP dropping, oliguria
Class IV - loss of vital signs, no urine output
Types of shock
Hemorrhagic
Septic/Distributive
Obstructive
Cardiogenic
Septic shock
Low systemic vascular resistance
High cardiac output
Low wedge pressure
Hemorrhagic shock
High systemic vascular resistance
Normal cardiac output
Low wedge pressure
Cardiogenic shock
High systemic vascular volume
Low cardiac output
High wedge pressure
What clotting factors are in FFP?
FFP provides factors II, V, VIII, IX, X, XI, and antithrombin III and fibrinogen (lower concentration than cryo)
What clotting factors are in cryoprecipitate?
fibrinogen (higher concentration), von Willebrand factor, factor VIII, factor XIII
What is the massive transfusion protocol in OB?
1:1:6 - pRBC : plasma : platelets
(different in every hospital, may be 1:1:1 or 1:1:2)
What is the goal level for fibrinogen in a hemorrhage?
> 100 or >150
What electrolyte abnormalities can occur with massive transfusions?
HypoCa
Hyper K
Due to citrate in pRBC
When to transfuse platelets?
<50 in massive bleeding
<10 for prophylaxis
<20 for procedures
What is the definition of massive transfusion?
> 6u within 2 hours
replacement of >50% of blood volumes
10U within 24h
what are adverse effects of massive transfusions?
Volume overload
HypoCa
HyperK
HypoMag
Hypothermia
Metabolic alkalosis (citrate)
DIC
What is the fluid resuscitation for septic shock?
30 cc/kg/hr