Critical Care Flashcards
What are the contrindications for surgery?
- Assess general health
- Stage IIIb or IV (i.e. metastases present)
- FEV1 < 1.5 litres is considered a general cut-off point*
- Malignant pleural effusion
- Tumour near hilum
- Vocal cord paralysis
- SVC obstruction
What are some examples of a muscle relaxant?
- Suxamethonium - best for RSI
- Vecuronium - slow and not used for RSI
What drugs are used for induction of anaesthesia?
- Ketamine
- Nitrous oxide
- Propofol
How does a depolarising neuromuscular drug like suxamethonium work?
Nicotinic acetylcholine agonist
What are the adverse effects of suxamethonium?
- Malignant hyperthermia
- Hyperkalaemia
What drug is important to prescribe before surgery for a patient taking steroids?
Hydrocortisone
What is the best induction agent for haemodynamically unstable patients?
Katamine
What is the most common bacteria for infecting post op wounds?
Staph aureus
What does an isoalted fever within 24 hours of operation mean?
Physiologocal reaction to operation
How long before surgery does the oral contraceptive pill need to be stopped?
4 weeks
What can a new onset AF mean after a gastrointestinal surgery?
Anastomotic leak
WHAT ARE THE MOST LIKELY CAUSES OF POST-OP PYREXIA (0-5 DAYS)
- Blood transfusion
- Cellulitis
- Urinary tract infection
- Physiological systemic inflammatory reaction (usually within a day following the operation)
- Pulmonary atelectasis - this if often listed but the evidence base to support this link is limited
What are the most likely caues of post-operative pyrexia (>5 days)?
- Venous thromboembolism
- Pneumonia
- Wound infection
- Anastomotic leak
What is the antidote to benzodiazepines?
Flumanzenil
What are the general rule of thumb for patients taking diabetic medication and surgery?
- Patients treated with insulin who have good glycaemic control (HbA1c < 69 mmol/mol) and are undergoing minor procedures, can be managed during the operative period by adjustment of their usual insulin regimen
- (Surgery requiring a long fasting period of more than one missed meal) or whose diabetes is poorly controlled, will usually require a variable rate intravenous insulin infusion (VRIII)
- Most patients taking only oral antidiabetic drugs may be managed by manipulating medication on the day of surgery, depending on the particular drug. There are some exceptions to this:
- if more than one meal is to be missed
- patients with poor glycaemic control
- risk of renal injury (e.g. low eGFR, contrast being used)
- in such cases a VRIII should be used
What is first line for patients with low urine after an operation?
500ml 0.9% normal saline fluid challenge
What can cause excessive bleeding in surgery?
Intra-operative hypothermia
What is the antidote to local anesthetic?
Lipid emulsion
What is the prefered method of feeding for a comatose, intubated patient?
NG tube
Which vein is total parenteral nutrition delivered through?
Subclavian line
What should warfarin be changed to pre-operatively?
LMWH
What is the treatment of malignant hyperthermia?
Dantrolene