Crisis Scenarios Flashcards
What process occurs to cause a bronchospasm?
Reflex Bronchiolar Constriction
What are the two mechanisms in which bronchospasms occur?
Centrally mediated
Local reaction
What two things occur in a bronchospasm that would cause air trapping and hyperinflation?
Constriction
Mucus hyper secretion
What complication could occur from excessive air trapping after a bronchospasm has occurred?
May result in pneumothorax
How would a bronchospasm eventually lead to cardiac collapse?
Alveolar distention increases intrathoracic pressure
Decreased venous return and cardiac output
Results in cardiac collapse
What are the causes of a bronchospasm?
Airway Manipulation Noxious Stimuli Cold Air Airway Irritants Acute Exposure to Allergens Stress of Surgery Histamine Releasing Medications (morphine, vancomycin, atracurium)
What other pathologies should be ruled out from wheezing?
Pneumothorax, endotracheal tube obstruction, anaphylaxis, pulmonary edema, pulmonary aspiration
What are the signs of a bronchospasm that an anesthetic provider may see?
Mucus Hyper secretion
High inspiratory pressures
Blunted expiratory CO2 waveform
Hypoxemia
How might an awake patient present with a bronchospasm?
Tachypnea & Dyspnea
What can wheezing tell us about a bronchospasm?
Degree of wheezing is a poor indicator of the extent of obstruction
What is the immediate treatment for a bronchospasm in the OR setting?
Check endotracheal tube position for carinal stimulation
Deepen the level of anesthetic, volatile agents are usually sufficient, if ventilation impaired, use IV sedative
Increase FiO2 to 100%
Administer a short-acting β2-agonist
What are some additional treatments for a bronchospasm if unable to relax the tissue?
Administer IV/IM epinephrine (10 mcg/kg)
Administer IV corticosteroids (Hyrdrocortisone 2-4 mg/kg)
Consider IV aminophylline if long term mechanical ventilation is planned
When does negative pressure pulmonary edema occur?
Usually occurs during emergence
What two events usually cause negative pressure pulmonary edema?
Result of two events:
Airway obstruction
Patient initiated forceful breath
What type of pulmonary edema is experienced by patients with negative pressure pulmonary edema?
Non-cardiogenic
What physiologic process occurs with negative pressure pulmonary edema?
Forceful inhalation attempt against a “closed glottis” creates extreme negative intrapleural pressure
Increased pulmonary transcapillary hydrostatic pressure
Rapid movement of fluid into lung interstitium, pulmonary lymphatic system overwhelmed
What is the primary cause of NPPE?
Laryngospasm
What other processes can also contribute to causing NPPE?
Airway Obstruction
Forceful inhalation
What other forms of pulmonary edema should be ruled out when considering NPPE?
Congestive heart failure & fluid overload
Acute respiratory distress syndrome
Aspirate gastric contents
How does NPPE present once the laryngospasm has resolved?
Bilateral rales heard on auscultation
Rapid onset
May progress to hypoxemia
What is a late sign of NPPE?
Frothy, pink sputum or frank bloody secretions indicate alveolar injury
What is the most important components in treating NPPE?
Quick recognition is critical (vigilance) critical to treat before hypoxia and alveolar injury
What is the typical treatment for NPPE?
Identify and resolve airway obstruction Supportive Therapies, oxygen & CPAP May require (re)intubation for mechanical ventilator support
What medications may be used to treat symptoms related to NPPE?
Consider steroids to stabilize capillary membranes
Important! – Diuretics are not always indicated
What is the typical treatment for NPPE?
Identify and resolve airway obstruction Supportive Therapies, oxygen & CPAP May require (re)intubation for mechanical ventilator support
What is pulmonary aspiration?
Misdirection of oropharyngeal or gastric contents into the larynx and lower respiratory tract.
What is another name for Aspiration Pneumonitis?
Mendelson’s syndrome
How does an infection occur after aspiration if the fluid is acidic?
Acid aspiration pneumonitis reduces host defenses, increasing the risk of superinfection
Infection develops if aspirated material is colonized with bacteria, or when airway burns allow infection to develop from commensal pathogens.