CREASY

Question 1

What stimulates extravillous trophoblast invasion? Inhibit it?

Answer 1

EGF and IL-beta stimulate extravillous trophoblast invasion. TGF-beta inhibits it.

Question 2

Regulates cell proliferation?

Regulates cell differentiation?

Answer 2

IGF responsible for regulation of cell proliferation

TGF-alpha and EGF regulate differentiation

Question 3

What placenta hormone stimulates FSH release?

Answer 3

Activin stimulates FSH release
Follistatin inhibits activin => less FSH release
Who cares? High levels activin in PreE, DM, PTL

Question 4

Risks fetal CHD if mom has…

Answer 4

AS 18%
Endocardial cushion 14%
VSD 9.5%
PS 6.5%
ASD 6%
Coarctation 4%
PDA 4%
TOF 2.5%

Question 5

Which TORCH does NOT cause hydrops?

Answer 5

Listeria

Question 6

Which TORCH do NOT cause IUGR?

Answer 6

Varicella and Parvo

Question 7

WHich TORCH does NOT cause microcephaly?

Answer 7

Parvo

Question 8

Which TORCH cause intracranial calcs?

Answer 8

CMV, Toxo, Syphilis

Question 9

Which TORCH cause ventriculomegaly?

Answer 9

CMV, Toxo

Question 10

Which TORCH cause limb abnormalities?

Answer 10

Varicella, Syphilis

Question 11

Which TORCH have cardiac effects?

Answer 11

Rubella (PDA / PA stenosis) and Parvo (cardiomegaly)

Question 12

Which cause placentomegaly?

Answer 12

Toxo, Parvo, Syphilis, (?) Listeria