Cranial Nervous System Drugs Flashcards
Used for psychiatric disorders, suppression of seizures, relief of pain, production of anesthesia
Cranial NS Drugs
Monoamine neurotransmitters
Dopamine
Epinephrine
Serotonin
Amino Acid neurotransmitters
Asparate
GABA
Glutamate
Glycine
Purine neurotransmitters
Adenosine
Adenosine monophosphate
Adenosine triphosphate
Opioid Peptides neurotransmitters
Dynorphines
Endorphins
Enkaphalins
Non-opiod Peptides neurotransmitters
Neurotensin
Oxytocin
Somatostatin
Substance P
Vasopressin
Other types of neurotransmitters
Acetylcholine
Histamine
GABA
Impedes the entry of drugs into the brain
Blood Brain Barrier
Adaptation to Prolonged Drug Use
Increased therapeutic effects
Decreased side effects
Tolerance and Physical Dependence
Dysregulation of the transmitters serotonin, norepinephrine, dopamine with Characteristics of inattentivenesss, inability to concentrate, restlessness, hyperactivity, inability to complete tasks and impulsivity
ADHD (Attention Deficit/Hyperactivity Disorder)
Characterized by falling asleep during normal waking activities [driving/ talking]; person with this disorder may be unable to move and may collapse
Narcolepsy
Methylprenidate
Increase child’s attention span and cognitive performance; Used to treat narcolepsy
Treatment of narcolepsy
Modafinil
Slowly progressive neurodegenerative disorder characterized by tremor, rigidity, postural instability and slowed movement
Parkinson’s Disease
Improve the patient’s ability to carry out activities of dally life
Therapeutic Goal
Group of disorders characterized by excessive excitablilityof neurons in the CNS
Epilepsy
Differentiate Seizure to Convulsion
Seizure is a general term that applies to all types of epilectic events while Convulsion is an abnormal motor phenomenon occur on the person with epilepsy
Differentiate Partial to Generalize Seizure
Partial seizure is an excitation that undergoes through limited spread from the focus to adjacent cortical areas while Generalize seizure is an excitation that spreads widely throughout both hemispheres of the brain
Relax skeletal muscles by disrupting the transmission of nerve impulses at the motor end plate
Neuromuscular blocking drugs
Non-depolarizing blocking drugs is a ____
Competitive/stabilizing drugs and used to prevent muscle contraction
