Cranial nerves Flashcards
Define nuclei
Collection of cell bodies
How many cranial nerves arise from the forebrain?
Two:
CN I - Olfactory
CN II - Optic
How is sensory information transmitted from the nasal cavity to the Olfactory nerve nucleus?
The receptors are located in the epithelium right at the top of our nasal cavity. They pass up through the roof of the nose and pass through the cribiform foramina in the cribiform plate. They then meet the olfactory bulbs which sits on top of the cribiform plate. The olfactory tracts then take it to the forebrain.
What is the function of the olfactory nerve?
Special sensory - smell
What is the name for loss of sense of smell?
anosmia
Name the causes of a loss of sense of smell
Common cold
Head injury - secondary to shearing forces and/or basilar skull fracture
Intracranial tumours at the base of the frontal lobes
Describe the path of the optic nerve
It leaves the orbit through the optic canal. It enters the cranial cavity and runs along the middle cranial fossa in close proximity to the pituitary gland. The optic nerves from each eye then mix at the optic chiasm. They then form optic tracts which travel to reach the lateral geniculate nucleus (a relay centre in the thalamus). The LGN then tranfers information to the primary visual cortex through the optic radiations.
What is the function of the optic nerve?
Special sensory - vision
How do we clinically test the optic nerve?
Visual tests - visual fields and Snellen charts
Pupillary light reflexes
We can also examine the optic nerve using fundoscopy
Why does the optic nerve swell in raised ICP?
It carries extensions of the meninges
What is the name given to a swollen optic disc observed in raised ICP?
Papillodema
Name the pattern of visual loss seen in a pituitary tumour
Bitemporal hemianopia
Where would a lesion be if visual loss was found in one eye?
The retina or optic nerve -once at the optic chiasm visual loss would be seen in both eyes.
Describe the route of the occulomotor nerve (CN III)
It runs from the midbrain through the cavernous sinus and exits into the orbit through the superior orbital fissure.
What are the functions of the occulomotor nerve?
Motor - supplies most of the extra-ocular muscles and LPS
Autonomic - supplies sphincter pupillae and the cilliary muscle
Describe how the occulomotor nerve can be affected by raised ICP.
The oculomotor nerve runs under the attachment for the tentorium cerebelli. Therefore, when you get raised intracrainal pressure the uncus of the temporal lobe can slip over the tentorium cerebelli and compress the oculomotor nerve.
What is the first sign of occulomotor nerve compression as a consequence of raised ICP?
Blown pupil
The parasympathetic fibres sit around the edge. When you get external compression these will be affected and you will get problems with pupil size and lens size. This is what happens when you get a blown pupil that is dilated. If you continue to compress the nerve, then the other functions will be lost.
How do you test the occulomotor nerve?
Inspect the eyelid and pupils
Eye movements
Pupillary light reflexes
What is the sign of a CN III palsy?
Pupil in the ‘down and out’ position with severe ptosis
What are the causes of a CN III palsy?
Raised intracranial pressure (tumour/haemorrhage)
Anneurysms (posterior communicating artery)
Vascular (secondary to diabetes/hypertension - typically pupil sparing)
Cavernous sinus thrombosis
What is the function of the trochlear nerve (CN IV)?
Motor - supplies superior oblique
Describe the path of the trochlear nerve?
The trochlear nerve also comes off the midbrain and runs through the cavernous sinus. It also exits the superior orbital fissure
What are the clinical signs of a CN IV palsy?
Diplopia (worse on a downward gaze)
Patients often correct the diplopia by tilting their head
What are the most common causes of a CN IV palsy?
Head injury - raised ICP
Congenital palsies in children
Name the three divisions of the trigeminal nerve
Opthalmic (Va) - runs through the superior orbital fissure and supplies sensation to the cornea and conjunctiva of the eye
Maxillary (Vb) - supplies the cheek
Mandibular (Vc) - supplies the jaw
What are the functions of the trigeminal nerve?
Main sensory nerve of the skin of the face and facial structures. It also supplies muscles of mastication (the mandibular branch mainly carries the motor supply for the muscles of mastication)