CR Chest Fair Game Flashcards
Case 103 - Fleischner Low Risk
= 4 mm
No Followup Needed
Case 103 - Fleischner Low Risk
>4 mm - 6 mm
CT at 12 mo
If no change no further fu needed
Case 103 - Fleischner Low Risk
>6 - 8 mm
CT at 6-12 months
Then 18-24 months if no change
Case 103 - Fleischner High Risk
= 4 mm
CT at 12 mo
If no change no further f/u
Case 103 - Fleischner High Risk
>4 - 6 mm
CT at 6 - 12 months
then
18-24 months if no change
Case 103 - Fleischner High Risk
>6 - 8 mm
CT at 3 - 6 months
then
9-12 months AND 24 months if no change
Case 103 - Fleischner High Risk
>8 mm
CT at 3, 9, and 24 months
or
PET vs Bx
Case 104
4 Causes of Tracheal Stenosis
Intubation Injury Malignancy TB Wegners Granulomatosis Amyloidosis
Case 105
Causes of Thymic Hyperplasia
Myasthenia Gravis Steroids or chemo Scleroderma Hyperthyroidism - Grave's Dz Hyperplasia Rheumatoid Arthritis Red Cell Aplasia
Case 105
How do you distinguish between Thymic hyperplasia and Neoplasia?
MRI using chemical shift artifact
Case 106 SPN - Which is most likely malignant? Solid Nodule Ground-glass Nodule Semi-solid Nodule of mixed attenuation (ground glass and solid)
Semi-solid Nodule of mixed attenuation
Case 106
What manifests as a solid nodule with a halo of ground glass?
BAC
Invasive Aspergillosis
Candidiasis
Cytomegalovirus
Case 106
In which clinical setting is Invasive Aspirgillosis most likely to occur?
Severely neutropenic patient
Case 106
BAC is a subtype of which cancer cell type?
Adenocarcinoma
Case 52
Five tumors that may affect central airways
Lung CA Hamartoma Carcinoid Mucoepidermoid Carcinoma Endobronchial mets
Case 52
T of TNM - For centrally obstructing neoplasm
Hilar but not all lung?
Entire lung?
T2
T3
Case 53
What organ systems are affected in Wegner’s Granulomatosis?
Lungs
Kidneys
Case 53
Define Wegener’s Granulomatosis
Necrotizing Vasculitis involving the upper respiratory tract, lungs, and kidneys
Limited form of the disease is confined to lungs
Case 53
Thoracic Manifestations of Wegener’s Granulomatosis
Multiple Lung Nodules / Masses Well Defined Cavitation Feeding Vessels Peripheral Distribution
Case 54
Multiple poorly defined lung nodules in immunosuppressed patient?
Fungal Pneumonia
- Invasive Aspergillus
Case 54
CT halo sign?
Ground glass surrounding a nodule indicating hemorrhage
Early sign in the course of infection with Aspergillus
Case 54
Most common fungal infection to affect immunosuppressed patients?
Pulmonary Aspergillosis
- Potentially lethal
- May undergo cavitation
Case 55
LAM v. EG
LAM EG
Thin uniform cysts Irregular bizzare
Diffuse Spares CP angles
Pneumothorax/Chylothorax Nodules
Nonsmoker Smoker
Case 55
Name two infiltrative lung diseases that are associated with a cystic pattern
LAM
Eosinophilic Granuloma - Langerhan’s Cell Histiocytosis
Case 55
Name two pleural complications of LAM
Chylothorax
Pneumothorax
Case 55
Describe the typical demographic features of LAM
Reproductive age female (35 yo avg)
Nonsmoker
Case 56
Most likely cause of focal consolidation in an HIV-positive patient?
Community Acquired Bacterial Pneumonia
Case 55
Differences in cysts between LAM vs LCH
LAM
- smooth cysts
- regular and uniform
LCH
- irregular / bizarre cysts
AND
- nodules which can cavitate
- Spares the Costophrenic Angles
Case 56
Second most common cause of focal consolidation in an HIV-positive patient?
TB
Case 56
How often does PCP present as a focal consolidation on an HIV-positive patient?
10%
Case 56
Are recurrent bacterial pneumonias an AIDS-defining illness?
Yes
Case 57
Low density nodes with peripheral enhancement?
TB
Case 57
Lymph node enlargement is most common in primary or post-primary TB?
Primary TB
Case 57
Primary TB - is LN enlargement more common in pediatric or adult patients?
Pediatric
Case 57
HIV-positive pt with TB - Are enlarged mediastinal LNs encountered more commonly in CD4 counts above or below 200/mm?
Below
Case 58
HIV-positive patient with bilateral perihilar ground glass densities
Pneumocystis jiroveci pneumonia - PCP
Case 59
Name four benign causes of calcified LNs
TB
Histoplasmosis
Sarcoidosis
Silicosis
Case 59
Neoplasm with ossified lymph nodes
Osteosarcoma
Case 60
Two infections that can result in rapidly growing nodules in non-AIDS immunosuppressed patients
Fungal
Septic Infarcts
Case 60
What organism is most closely associated with septic infarcts?
Staph aureus
Case 60
Three common sources of septic infarcts
Tricuspid Endocarditis
Indwelling Catheters
Prosthetic Devices
Case 60
List four features of septic infarcts
Poorly defined nodules that cavitate
Wedge Shaped
Peripheral and Basilar
Feeding Vessel
Case 61
Four radiographic signs of bronchopleural fistula
Space fails to fill with fluid
Abrupt decrease in air-fluid level
New air in previously opacified space
Contralateral shift of the mediastinum
Case 62
Right Apical Tumor - most common cell type?
Squamous Cell Carcinoma
Case 62
Name four absolute contraindications to surgical resection of superior sulcus tumors
Invasion of more than 50% of a vertebral body
Brachial Plexus invasion above T1
Esophageal Invasion
Tracheal invasion
Case 63
Irregular shaped cysts with some scattered nodules
Langerhan’s Cell Histiocytosis
- 90% smokers
- spares lung bases and CP angles
Case 64
Reticulonodular interstitial densities - three possible diagnosis
Drug toxicity
Lymphangetic carcinomatosis
Atypical Infection
Case 64
Malignancies commonly associated with lymphangitic carcinomatosis
Breast
Lung
Stomach
Colon
Case 64
Unilateral lymphangitic carcinomatosis
Lung CA
Case 65
Right apical mass with satellite nodules
Reactivation TB
Case 65
Satellite nodules - infection vs malignancy
Infection
Case 65
Most common sites for post-primary TB in the lung?
Apical and posterior segments of the upper lobes and superior segments of the lower lobes
Case 67
Fatty diffuse mediastinal widening
Mediastinal Lipomatosis
Case 67
Three risk factors for developing mediastinal lipomatosis
Obesity
Cushing’s Syndrome
Steroids
Case 68
Azygous continuation of the SVC - associated extravascular abnormality
Polysplenia
Case 68
Causes of Azygous Vein Enlargement
Vena Caval Obstruction
Tricuspid insufficiency
Right Sided Heart Failure
Case 69
What value is considered positive for pulmonary nodule enhancement?
> 15 HU is concerning for CA (specificity 58%)
Case 70
Diaphragmatic rupture - most common on L or R
Left
Case 70
Two most common causes of diaphragmatic rupture
Blunt Trauma
Penetrating Injury
Case 70
Diaphragmatic hernia - what is the most common organ herniated?
Stomach
Case 70
Signs of Diaphragmatic Rupture
NGT in the thorax Elevated hemidiaphragm Loss of normal diaphragm dome shape Changing Diaph levels on serial CxR Contralateral mediastinal shift Left pleural effusion
Case 71
Sternoclavicular dislocation
- Most common - ant vs post
Posterior
Case 71
Complications of posterior sternoclavicular joint dislocation
Injury to
- brachiocephalic / subclavian veins
- trachea
- esophagus
Case 72
Causes of unilateral absent perfusion on VQ Scan
Ascending Aortic Aneurysm Hilar Mass Dissection Pneumonectomy PA Sarcoma PA Hypoplasia / Agenesis
Case 72
Causes of Ascending Aortic Aneurysm
Connective Tissue Disorders (Marfan’s and Ehlers-Danlos)
Syphilis
Cystic Medial Necrosis
Case 73
Two complications of over inflated tracheostomy tube cuff
Tracheal Stricture
Tracheomalacia
Tracheal Rupture
Tracheoesophageal fistula
Case 73
Two types of fistulas that may occur as a tracheostomy tube complication
Tracheoesophageal
Tracheoarterial
Case 74
Characteristics of Rounded Atelectasis
Subpleural Round / Oval Sharply Marginated Posterior Lower Lobes Abuts Pleural Thickening
Case 75
Four causes of upper zone distribution of chronic infiltrative lung disease
Cystic Fibrosis Sarcoid Silicosis Berylliosis Langerhan's CH Coal Workers Pneumoconiosis Ankylosing Spondylitis
Case 75
Upper zone distribution with reticular and nodular pattern
Sarcoid
LCH
Case 75
Irregular bronchial dilation associated with pulmonary fiborisis
Traction bronchiectasis
Case 75
Laboratory test elevated in patients with sarcoidosis
Elevated Angiotensin-converting enzyme levels (ACE)
Case 76
Two entities associated with an ascending aortic aneurysm
Cystic Medial Necrosis
- Marfan’s
- Ehlers-Danlos)
Syphilis
Case 76
What is the difference between a true and false aneurysm?
True - intact aortic wall
False - disrupted aortic wall
Case 77
Centrally obstructing mass containing calcification
Carcinoid
Case 77
Are carcinoids benign or malignant?
Malignant
Case 77
Nuclear medicine studies for carcinoid?
Octreotide
Case 77
What percentage of carcinoids demonstrate calcification on CT?
30%
Case 77
Four characteristics of Carcinoid
Central (80%) Lobulated Calcification (30%) Near bifurcations Octreotide Scan
Case 78
Esophageal perforation due to repeated episodes of vomiting
Boerhaave’s Syndrome
Case 78
Three causes of esophageal perforation
Iatrogenic
Impacted foreign body
Obstructing neoplasm
Trauma
Case 79
HIV-positive patient with parahilar masses
Kaposi’s Sarcoma
Case 79
Most commonly involved organ system by Kaposi’s Sarcoma?
Skin
Case 79
Is Kaposi’s sarcoma (KS) gallium-avid?
No
Case 80
Define bulla
- Sharply demarcated airspace
- Measures more than1 cm
- Well defined wall measuring less than 1 mm
Case 80
Define bleb
Small - Less than 1 cm Gas space within - Visceral pleura - Subpleural lung
Case 80
Three potential complications of bullae
Pneumothorax
Infection
Hemorrhage
Case 81
Name 5 endobronchial Metastases
Thyroid Breast Kidney Colon Melanoma
Case 83
Pneumonia with a diffuse reticulonodular pattern
Varicella Zoster Pneumonia
Case 83
Overall incidence of pneumonia in patients with chickenpox?
15%
Case 83
Pregnant women - higher or lower incidence of VZ pneumonia?
Higher
Case 83
Typical appearance of healed varicella pneumonia
Multiple diffuse discrete pulmonary calcifications
Case 84
Four causes of unilateral enlarged apical cap
Abscess Lung CA Lymphoma Extrapleural Hematoma Extrapleural Metastasis Radiation Fibrosis
Case 85
Type of emphysema most closely associated with cigarette smoking
Centrilobular
Upper lobes
Case 86
How does drug toxicity present in the lungs?
Reticular interstitial opacities and ground glass densities
Case 86
What percentage of patients receiving bleomycin develop pulmonary toxicity?
4 %
Case 86
Does simultaneous chest radiation therapy increase or decrease the risk of bleomycin pulmonary toxicity?
Increase
Case 86
In a patient with bleomycin toxicity would you expect the patient’s diffusing capacity of carbon monoxide to be increased or decreased?
Decreased
Case 87
HIV positive patient - which fungal infection is likely to present with pulmonary nodules pleural effusion and lymph node enlargement?
Cryptococcus
Case 87
Which organ system is most commonly affected by cryptococcus?
Central Nervous System
Case 87
Besides CNS - which other organ systems are most commonly involved in disseminated Cryptococcal infection?
Bone and skin
Case 88
TNM Lung Cancer - Define N specifications
N0 - No mets N1 - Ipsilateal peripheral interlobar - Ipsilateral Hilar-interlobar N2 - Ipsilateral Mediastinal N3 - Supraclavicular Nodes - Contralateral Anything
Case 89
Most common cause of SVC syndrome?
Malignancy - Lung CA
Case 89
One common benign cause of SVC syndrome
Long term intravenous devices
Fibrosing mediastinitis
Case 89
Three mechanisms by which the SVC may become obstructed
Extrinsic Compression
Direct Invasion
Intraluminal Thrombus
Case 89
Typical Symptoms with SVC Obstruction
Edema of the face and neck
Headache
Visual disturbances
Reduced level of conciousness
Case 89
Diagnosis of SVC Obstruction requires what two things?
Decreased or Absent contrast in the SVC
Opacification of collateral vessels
Case 90
Periosteal reaction in association with pulmonary disease
Hypertrophic Pulmonary Osteoarthropathy (HPOA)
Case 90
Is HPOA symptomatic?
Yes
Case 92
How is hemophilia genetically transmitted?
X-linked recessive - transmitted by females but primarily affects males
Case 92
Name potential complications of intramuscular hemorrhage
Joint Contracture Ischemic Myopathy Neuropathy Pressure necrosis of adjacent bone Pseudotumor formation
Case 93
Two benign features of lytic bone lesions
Well circumscribed
Sclerotic Margins
Case 93
Lytic rib lesion with benign features - name two likely causes
Enchondroma Fibrous Dysplasia ABC Non-ossifying Fibroma *LCH
Case 93
Chronic infiltrative lung disease and lucent bone lesions
LCH
Case 93
Primary neoplasms frequently associated with lytic bone mets
Lung
Breast
Kidney
Thyroid
Case 93
McCune-Albright Syndrome
Polyostotic fibrous dysplasia
Cafe au lait skin lesions
Precocious Puberty
Case 94
Dressler’s Syndrome
The development of pericardial and pleural effusions 2 to 10 weeks after an MI
Case 95
Three classifications of bronchiectasis
Cylindrical
Varicose
Cystic
Case 95
Name three congenital or developmental disorders associated with bronchiectasis
Cystic Fibrosis Yellow Nail Synd Kartagner's Mounier-Kuhn Synd Young's Syndrome Williams-Campbelll
Case 96
Name causes of thoracic esophageal dysmotility
Achalasia Amyloidosis
Scleroderma Drugs
Chaga’s Dz
Case 97
Atypical cavitary infection from SW United States
Coccidiomycosis
Case 97
What is the typical pattern associated with disseminated coccidioidomycosis infection?
Cavities - initial or chronic form of this infection?
Multiple small nodules
Chronic
Case 98
Define ground glass opacity
Hazy increased opacity of lungs with preservation of bronchial and vascular margin visibility
Case 98
Name two technical features that are necessary components of HRCT imaging
Thin collimation (1-2 mm) High Spatial Frequency reconstruction algorithm
Case 99
Retrosternal densities
Most likely cause?
Lymphadenopathy
Case 99
Most common site of enlarged nodes in patients with breast CA
Axilla
Case 99
Medial breast lymphatics drain in to?
Internal mammary lymph nodes
Case 100
Complications of TTNB
Pneumothorax Seeding the Bx Track
Chest Tube Air Embolism
Hemoptysis
Case 101
Four entities associated with mucoid impaction and mucocele formation
Allergic Broncho-pulmonary Aspergillosis (ABPA)
Obstructing Endobronchial Tumor
Congenital Bronchial Atresia
Cystic Fibrosis
Case 101
Name 6 congenital conditions that affect the bronchi
Congenital Bronchiectasis (Cystic Fibrosis, W.C. Synd) Bronchial Isomerism Syndrome Bronchial Atresia Supernumerary Bronchus Pig Bronchus Cardiac Bronchus
Case 101
Which anatomic structures enable collateral air drift to occur in the lungs?
Interalveolar pores of Kohn
Canals of Lambert
Case 101
Give four possible etiologies of a tubular opacity on imaging studies
Mucocele / Mucoid Impaction
AVM
PAVPR ( partial anomalous pulmonary venous return)
Pulmonary Varix
Case 102
Centrilobular ground glass opacities DDx
Hypersensitivity Pneumonitis Bronchiolitis
RB-ILD PCP
PLCH
Case 102
What anatomic structures are located in the central core of the secondary pulmonary lobule?
Lobular Bronchiole
Pulmonary Artery
Peribronchovascular Lymphatics
Case 102
Seven pulmonary diseases associated with smoking
COPD DIP (Desquamative)
Lung CA Chronic Bronchitis
PLCH Respiratory Bronchiolitis
RB-ILD
Case 102
What type of immune reaction is associated with hypersensitivity pneumonitis?
Type IV
Case 103 - Fleischner Low Risk
> 8 mm
CT at 3, 9, 24 months
or
PET vs Bx