CPT HF, hypertension and diuretics

Question 1

bendroflumethiazde and indapamide

Answer 1

thiazide and thiazide-like

Question 2

loop diuretic

Answer 2

bumetanide and furosemide

Question 3

diuretic: K+ sparing

Answer 3

amiloride

Question 4

diuretic: aldosterone antagonist

Answer 4

spironolactone

Question 5

B-adrenoceptor blockers

Answer 5

-olol

atenolol, labetalol, metoprolol, propranolol, bisoprolol

Question 6

a-adreonceptor blockers

Answer 6

doxazosin and tamsulosin

Question 7

ACEi

Answer 7

lisinopril and ramipril

Question 8

ARBs

Answer 8

candesartan and losartan

Question 9

CCBs

dyhydropyridine and non-dyhydropyrdine

Answer 9

D - amplopidine, nifedipine, nimopidine
Phenylalkylamines - verapamil
Benzothiazipines - diltiazem

Question 10

DDI

ACEi & K+ sparing

Answer 10

increased hyperkalaemia -> cardiac problems

Question 11

DDI

aminoglycosides & loop diuretics

Answer 11

ototoxicity and nephrotoxicity

Question 12

DDI

digoxin & thiazide/loop

Answer 12

hypokalaemia -> increased digoxin binding and toxicity

Question 13

DDI

B-blokers & thiazides

Answer 13

hyperglycaemia, hyperlipidaemia, hyperuricaemia

Question 14

DDI

steroids & thiazide/loop

Answer 14

lithium toxicity (thiazides)
reduced lithium levels (loop)

Question 15

DDI

carbamazepine & thiazides

Answer 15

increased risk of hyponatraemia

Question 16

DDI

B-blocker & non-dihydropyridine (CCB)

Answer 16

cardiovascular side affects

Question 17

DDI

a-blocker & dihydropyridine

Answer 17

hypotension

Question 18

DDI

amlopidine and simvastatin

Answer 18

increase efficacy of the statin