COVID-19 Flashcards
What family of viruses does COVID-19 belong to?
Coronaviruses
A large family of viruses including
- SARS: severe acute respiratory syndrome
- MERS: middle eastern respiratory syndrome
- Seasonal coronavirus
What are the features of coronaviruses?
Crown like spikes on the surface
Enveloped RNA based
Who can coronaviruses infect?
Humans and animals
(is zoonotic = large number circulating in animals)
What are the different types of coronaviruses?
Alpha - related to bats
Beta - related to bats (COVID-19)
Gamma - related to birds
Delta - related to pigs
What was the initial and intermediate hosts for COVID-19 (and other coronaviruses)?
Initial host = bats
Intermediate = don’t know!
- MERS = camel
- SARS = cats
How is COVID-19 transmitted?
Cough
Sneeze
Touch
How does coronavirus attack/infect the body?
- Enter nose/respiratory tract
- Use binders on human cells to enter
- Hijack enzymes and replicate virus protein
- Package it up
- Leave cell to infect more cells
How does the immune system respond?
Via T and B cells
T cells = direct attack
B cells = memory attack
How long can COVID-19 survive on certain surfaces?
- Copper = 3
- Copper = 4
- Cardboard = 24
- Steel = 48
- Plastic = 72
- Glass = 96
Define the term epidemic
Refers to an increase, often sudden, in the number of cases of a disease above what is normally expected in that population in that area.
e.g. Ebola
Define the term endemic
Refers to the constant presence and/or unusual prevalence of a disease/infectious agent in a population within a geography area.
e.g. malaria
Define the term outbreak
Carries same definition of epidemic but is often used for a more limited geographic area.
e.g. cholera
Define the term pandemic
Refers to an epidemic that has spread over several countries or continents usually affecting a large number of people.
e.g. COVID-19
What are variants of interest?
Genetic traits which predict
- Greater transmissibility
- More severe disease
- Evasion of immune system or testing
What are variants of concern?
Observed to
- Have increased transmissibility
- Cause more serious infection
- Cause reinfection or infection of immunised