COVID Flashcards
1
Q
Why did we contain SARS?
A
Because most people who got it were quite symptomatic and so less transmission
2
Q
How does SARS CoV2 enter the cells?
A
ACE2
3
Q
What are the natural reservoirs of SARS- CoV2?
A
Bats and Pangolins
4
Q
what is the time course of SARS CoV2
A
Day 3 = positive and infectious
Day 5 = symptomatic
Day 8 onwards = virus positive and not infectious
OR
Day 7 - 10 = virus dissemination and immunopathology (cytokine storm in the lungs)
5
Q
What is a cheap and effective medication used to treat patients hospitalised in ITU because of SARS- CoV2?
A
Dexamethasone
6
Q
what vaccine was implemented during the pandemic?
A
mRNA vaccines (nucleoside-modified)
uses ‘locks’ to keep virus in prefusion spike
7
Q
What mutations are occurring in different strains of COVID?
A
spike mutations
