Corticosteroids

Question 0

Diurnal steroid cycle

Answer 0

Production of body’s own glucose roads follows diurnal cycle
Give at 8 am morning
Cortisol levels highest in morning

Question 1

Indications for inhaled corticosteroids

Answer 1

Maintenance control therapy of chronic asthma
Copd
Management of seasonal allergies

Question 2

Pharmacology of corticosteroids

Answer 2

The inflammatory process can be reduced or blocked by anti-inflammatory corticosteroids
Inhibit the activity of inflammatory cells and mediators of inflammation
Used to manage acute and chronic asthma
These agents have nonspecific anti-inflammatory actions and serious systemic side effects and are more effective when given systematically or through IV

Question 3

Corticosteroids mode of action

Answer 3

To induce gene expression for anti-inflammatory proteins and receptors
To suppress gene expression for pro inflammatory proteins

Question 4

Fluticasone/salmeterol

Answer 4

Advair

Question 5

Budesonide/formoterol

Answer 5

Symbicort

Question 6

Mometasone/formoterol

Answer 6

Dulera

Question 7

Beclomethasone dipropionate mdi

Answer 7

Qvar
40 and 80 ug puff
50-60% lung deposition

Question 8

Flunisolide

Answer 8

Aerospan

80 ug puff bid

Question 9

Budesonide dpi and solution

Answer 9

Pulmicort turbuhaler

Question 10

Mometasone furoate

Answer 10

Asmanex twisthaler

4 years old patients

Question 11

Ciclesonide

Answer 11

Alvesco 80 and 160 ug bid

Prodrug decreases the development of Candida albicans infection in mouth

Question 12

Fluticasone propionate mdi and dpi

Answer 12

Flovent hfa or discus