Corrosive Injury Of The Oesophagus Flashcards
What is the definition of corrosive injuries to the oesophagus?
Implies there has been tissue damage due to a chemical reaction on the oesophageal wall. Referred to as
- Caustic injury
- Caustic Burns
- Caustic ingestion
What are few examples of these caustic agents
These agents are usually acidic or alkaline, available in various forms like crystals and liquids. They include:
- Car battery acid
- Pool acid
- Bleaches
- Detergents
- Pool cleaners
- Drain cleaners
What is the immediate threat of ingesting one of these caustic agents?
Involvement of the airway passage
Note that the oesophagus has 3 narrowings which are more prone to caustic injury .
What is the reason for this?
This is because there is a relative hold up of the liquid in these areas
Severity of the injury is determined by 4 main determinants. What are they?
Amount of agent consumed
Type of agent consumed
Concentration of the agent consumed
Duration of contact
What is the critical PH of an alkaline agent required to cause severe oesophageal injury?
PH of 11 and above
What does the term “Lye” refer to?
This the general term used for alkaline cleaning products
What are the dangers of ingesting solid lye products (crystals)?
- Tend to adhere to the mucosa
- Cause deep burns where they adhere
- Rarely cause injury beyond the oropharynx and proximal oesophagus
What are the dangers of ingesting liquid lye products (crystals)?
- When swallowed, the liquid covers the entirety of the oesophagus.
- Injury occurs easily within seconds or minutes
What type of necrosis takes place in alkaline corrosive injury?
Liquefactive necrosis
What are the 3 phases of alkaline corrosive injury:
- Liquefactive necrosis
- Reparative phase
- Scar retraction
Explain phase 1 of an alkaline corrosive injury:
Liquefactive necrosis:
- Happens between 1-5 days
- Diffuses into deeper lawyers
Explain phase 2 of an alkaline corrosive injury:
Reparative phase:
- Begins from 5th day
- Development of granulation tissue
- Collagen deposition (peaks in week 2).
- Mucosal re-epithelialisation
> Fibroblast and collagen matrix results in severe oesophageal dysmotility
Explain phase 3 of an alkaline corrosive injury:
Scar retraction
- Occurs in both longitudinal and circumferential direction
- Results in both oesophageal shortening and stricture formation.
What type of necrosis takes place in acid injuries?
Coagulation necrosis
- The coagulum helps to limit penetration into deeper layers