Cornea Vol. 2 Flashcards

1
Q

What is the refractive index of the cornea?

A

1.376

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2
Q

What is the average radius curvature of the central cornea?

A

7.8 mm

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3
Q

What is the average power of the cornea in diopters?

A

43 D

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4
Q

What is the average total power of the human eye in diopters?

A

59 D

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5
Q

What is the major source of astigmatism in the optical system?

A

Cornea

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6
Q

What type of epithelium composes the corneal epithelium?

A

Stratified squamous epithelium

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7
Q

How thick is the corneal epithelium?

A

0.05 mm

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8
Q

What percentage of the total corneal thickness does the corneal epithelium constitute?

A

Approx. 5%

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9
Q

What structures of the corneal epithelium prevent penetration of the tear fluid into the stroma.?

A

Tight junctions

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10
Q

What type of collagen makes up the basement membrane of the corneal epithelium?

A

Type IV collagen

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11
Q

What types of collagen are found in the corneal stroma?

A

Types I, V, and VI

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12
Q

What are two major proteoglycans found in the corneal stroma?

A

Decorin and lumican

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13
Q

How does the refractive index of the cornea change from anterior to posterior?

A

Decreases from anterior to posterior

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14
Q

What is the normal percentage of water content of the corneal stroma?

A

78%

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15
Q

What creates the swelling pressure of the corneal stroma?

A

Negatively charged proteoglycans proteoglycans that repel each other

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16
Q

Where is the density of keratocytes in the corneal stroma the highest?

A

Anterior stroma

17
Q

How thick is Descemet’s membrane at birth?

A

3 um

18
Q

How thick Is Deseret’s membrane In the adult?

A

10 to 12 um

19
Q

How do radial incisions change the shape of the cornea?

A

Radial incisions cause flattening in the meridian of the incision and flattening 90 degrees away

20
Q

How do tangential incisions change the shape of the cornea?

A

Tangential incisions cause flattening of the meridian of the incision and steepening 90 degrees away

21
Q

What factor does the effect of incisional surgery greatly depend on?

A

Hydration of the corneal stroma

22
Q

What can occur to the refractive error of a patient exposed to high altitude or low P02?

A

Hyperopic shift

23
Q

What type of diurnal shift can occur in patient following radial keratotomy due to stromal swelling?

A

Hyperopic shift in the morning

24
Q

What optical characteristic of the cornea makes sclerotic scatter possible?

A

Total internal reflection

25
Q

What stain is used to detect disruption of intercellular junctions of the cornea?

A

Fluorescein

26
Q

When compared to fluorescein, what corneal stain is more toxic and more likely to induce reflex tearing?

A

Rose bengal

27
Q

What is an Axenfeld loop?

A

lntrascleral loop of long posterior ciliary nerve

28
Q

What corneal stain is a photosensitizer and also has antiviral properties?

A

Rose bengal

29
Q

What condition is characterized by lower conjunctival staining?

A

Meibomian gland dysfunction