CORE - GI Flashcards
Normal liver attenuation
40-60 HU; >75 HU = hyperattenuating; hypoattenuating = less than spleen on NECT or 25 HU less than spleen on CECT
Hot quadrate sign
SVC occlusion
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Empty gallbladder fossa sign
Hepatic parenchyma surrounding GB replaced by fat in early cirrhosis
Criteria for distended GB
> 4 cm
Porcelain GB
- Calcified GB wall
- Increased risk of gallbladder cancer
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Criteria for GB wall thickening
> 3 mm
Thoratrast complications (liver)
- Angiosarcoma
- HCC
- Cholangiocarcinoma
Indications for gallbladder polyp removal
> 10 mm
or
> 6 mm + suspicious features
Most common type of gallbladder polyp
Cholesterol polyps
Transplant type with highest incidence of PTLD
small bowel > pancreas > heart & lung
Most common organ involved in PTLD
Liver
Multiple hepatic adenomas
Von Gierke disease or adenomatosis
Most common hepatitis virus to cause HCC worldwide
Hepatitis B (can occur in acute or chronic HepB infection)
Light bulb sign
Hemangioma - appears very T2 bright
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Micronodular cirrhosis
Nodules are < 3 mm
Associated with alcoholism
Macronodular cirrhosis
Nodules are >3 mm
Associated with viral hepatitis
Starry sky pattern
Periportal edema in the setting of hepatitis
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Hydatid sand
Echinococcal cyst
Fine sediment caused by separation of membranes
Can occur in liver or spleen
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Water lily sign
Echinococcal cyst
Undulating membrane
Can occur in liver or spleen
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Daughter cysts
Echinococcal cyst within a larger cyst
Can occur in liver or spleen
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Hepatic candidiasis
Multipe small “targetoid” or “bull’s eye” lesions
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Hepatic PCP
Punctate echogenic foci in liver +/- spleen
After inhaled pentamidine
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Amebic abscess
Entamoeba histolytica
Characteristic location is near dome of right lobe
Most common complication of amebic abscess
Pleuropulmonary amebiasis (20-35%) > peritoneal, pericardial or renal amebiasis
Amebic abscess in the left hepatic lobe
May rupture into pericardium, therefore, emergent drainage needed
Primary hemochromatosis
Liver + pancreas
Long term complications: cirrhosis, diabetes, cardiomyopathy, arthritis, bronze skin
Inherited (genetic)
Tx = phlebotomy
Secondary hemochromatosis
Liver, spleen, and bone marrow
Due to chronic illness or multiple transfusions
Tx = chelation
Scalloping of the liver
Pseudomyxoma peritonei
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Periportal hypoechoic infiltration
Kaposi’s sarcoma (in AIDS patient)
Increased liver signal on out-of-phase
Hemochromatosis
Liver is very T2 dark
Anti-mitochondrial antibodies
primary biliary cirrhosis
Mirizzi syndrome
stone in cystic duct causing obstruction of CHD; assoc. with GB carcinoma
Injury to bare area of the liver
retroperitoneal bleed
Falciform ligament location
divides segments 2/3 and 4; ligamentum teres runs within
Cantlie’s line
divides the liver into the functional left and right hepatic lobes; between segments 5/8 and 4
Most common hepatic vascular variant
replaced RHA
Most common biliary ductal variant
right posterior segmental branch draining into the left hepatic duct
T1 characteristics of liver-pancreas-spleen
pancreas (brightest) > liver > spleen (darkest)
Regenerative and dysplastic nodules
T2 iso/dark, no arterial enhancement; high grade dysplastic nodules may demonstrate arterial enhancement
Nodule within a nodule
HCC (T2 bright) within a regenerative/dysplastic nodule (T2 dark); suggests malignant transformation
Well-differentiated HCC
enhances during hepatobiliary phase with Eovist (normal HCC does not)
Massively dilated hepatic artery
HHT; multiple hepatic and pulmonic AVMs
Solitary pyogenic hepatic abscess
Klebsiella
Multiple pyogenic hepatic abscesses
E. coli
Gas in a hepatic abscess
suggests pyogenic etiology
Tortoise shell appearance of the liver
schistosomiasis
Hemangioma ultrasound characteristics (liver)
hyperechoic (unless liver is fatty), no internal flow, posterior acoustic enhancement
Most common benign liver neoplasm
hemangioma > FNH
T1 hyper- or isointense liver lesion DDx
HCC, FNH, hepatic adenoma
Threshold for hepatic adenoma resection
>5 cm
Liver lesion with intralesional (microscopic) fat
HCC, hepatic adenoma
Non-enhancing T2 dark central scar
fibrolamellar HCC (gallium avid)
Late-enhancing T2 bright central scar
FNH (sulfur colloid avid, visible on HIDA)
Most common location for a hepatic adenoma
right hepatic lobe
Alternate name for Eovist
Gd-EOB-DTPA
Risk factors for cholangiocarcinoma
PSC, choledochal cysts, recurrent pyogenic cholangitis (chlonorchis senesis), FAP, thorotrast
Cholangiocarcinoma
delayed enhancement, ductal dilatation, capsular retraction
Risk factors for hepatic angiosarcoma
arsenic (25 year latent period), polyvinyl chloride exposure, radiation, thorotrast, hemochromatosis, NF1
Calcified liver mets
mucinous neoplasms (stomach, colon, ovary, breast)
Hypervascular liver mets
hemorrhagic mets + carcinoid, PNET
NASH
hepatic steatosis + abnormal LFTs
Budd-Chiari
most commonly: hypercoagulable state => hepatic vein thrombosis => nutmeg liver +/- multiple regenerative nodules
Nutmeg liver DDx
Budd-Chiari, hepatic veno-occlusive disease, right heart failure, constrictive pericarditis
Caudate lobe hypertrophy DDx
cirrhosis, Budd-Chiari, PSC, PBC
Causes of hepatic veno-occlusive disease
post-BMT, chemotherapy, Jamaican bush tea (alkaloids); occlusion of post-sinusoidal venules with patent hepatic veins; caudate lobe is NOT spared
Pseudocirrhosis
treated breast cancer mets; causes capsular retraction
Donor liver segments
right lobe (segments 5-8) in adults; segments 2/3 in peds
Indications for liver transplant
hepatitis C, alcoholic cirrhosis, HCC, PSC, cryptogenic cirrhosis (NASH)
Contraindications to liver transplant
extrahepatic malignancy, advanced cardiac or pulmonary disease, active substance abuse
Impending thrombosis post-liver transplant
days 3-10; normal waveform => loss of diastolic flow => tardus parvus arterial waveform + RI <0.5 => loss of hepatic artery waveform
“Central regenerative hypertrophy”
pattern in cirrhosis due to PSC
Dilated intrahepatic bile ducts in the setting of cirrhosis
PSC
Withered tree on MRCP
PSC
AIDS cholangiopathy
findings of PSC + papillary stenosis; classically due to cryptospordium infection (or CMV)
Malignant biliary strictures
long with shouldering (vs. benign strictures which are short and abrupt)
Charcot triad
fever, jaundice, RUQ pain; in ascending cholangitis
Recurrent pyogenic cholangitis
left lobe predominant disease burden
Primary biliary cirrhosis
autoimmune, middle-aged women, irregular intrahepatic ducts, normal extrahepatic ducts; increased risk of HCC
Most common type of choledochal cyst
type 1
Caroli’s disease associations
polycystic kidney disease, medullary sponge kidney
Complications of choledochal cysts
cholangiocarcinoma, bile duct stones, cirrhosis, cholangitis; Tx is resection
Duct of Luschka
accessory cystic duct; may cause bile leak after cholecystectomy
Multiple “halo” or “targetoid” liver masses
epitheloid hemangioendothelioma
Lace-like hepatic fibrosis
primary biliary cirrhosis
Cholesterolosis
cholesterol deposition within the gallbladder lamina propria; similar appearance to adenomyosis
Diffuse hepatic hypoattenuation
steatosis, amyloidosis (may also be focal)
Diffuse hepatic hyperattenuation
hemochromatosis, hemosiderosis, Wilson’s disease, amiodarone, methotrexate, gold, glycogen excess
Wilson’s disease
AR; hyperattenuating liver with multiple nodules; progresses to cirrhosis
Caudate-to-right lobe size ratio suggesting cirrhosis
>0.65
von Meyenburg complexes
biliary hamartomas; small, irregular, non-communicating
Caroli syndrome
Caroli disease + hepatic fibrosis
Central dot sign (liver)
Caroli disease
Gallbladder wall thickening with intraluminal membranes
gangrenous cholecystitis; Tx emergent cholecystectomy (or -ostomy)
Most common islet cell tumor
insulinoma (almost always benign) > gastrinoma > glucagonoma
Gastrinoma
Zollinger-Ellison syndrome; assoc. with MEN1
Gastrinoma triangle
typical location; bounded by junction of cystic duct, CBD and duodenum inferiorly, and pancreas medially
Serous cystadenoma
grandmother tumor; benign; hypervascular, head most commonly, peripheral calcifications; assoc. with VHL; resection only if symptoms related to mass effect
Mucinous cystadenoma
mother tumor; pre-malignant; body and tail most commonly; Tx resection
Solid and papillary epithelial neoplasm (SPEN)
daughter tumor; tail most commonly; heterogenous, prone to hemorrhage; Tx resection (malignant potential)
Intraductal papillary mucinous neoplasm (IPMN)
grandfather tumor; main branch has higher malignant potential
Indications for IPMN resection
>3 cm, mural nodularity, or ductal dilatation >10 mm
Lipase hypersecretion syndrome
syndrome related to acinar cell carcinoma (rare, aggressive, elderly males); subcutaneous fat necrosis, eosinophilia, bone infarcts=>polyarthralgias
Whipple triad
clinical symptoms of insulinoma: hypoglycemia, symptoms of hypoglycemia, alleviation with glucose administration
Crossing duct sign
pancreas divisum; CBD crosses the main pancreatic duct (which drains via minor papilla)
VHL associations (pancreas)
pancreatic cysts; increased risk of serous cystadenoma and PNETs
Sausage pancreas + associations
autoimmune pancreatitis; assoc. with IgG-4 and Sjogren’s
Wide duodenal sweep (fluoro)
mass effect from pancreatic cancer
Dorsal pancreatic agenesis
increased risk of diabetes; assoc. with polysplenia
Pancreatic lipomatosis DDx
CF, Schwachmann-Diamond, obesity, Cushing’s, chronic steroids, hyperlipidemia
Pancreatic agenesis
no duct present (vs. lipomatosis which still has a duct)
Next step in suspected pancreatic duct injury
MRCP or ERCP
Pancreas in CF
fibrosis, lipomatosis, or cystosis
Causes of acute pancreatitis
gallstones, EtOH, scorpion bite, ERCP, valproic acid, trauma, ascariasis
Pancreas hypoechoic relative to the liver
inflammation/edema
Most common anatomic variant of the pancreas
pancreas divisum; increased risk of pancreatitis
Complication(s) of chronic pancreatitis
increased risk of pancreatic cancer
Loss of T1 signal in the pancreas
suggests fibrosis (normally very T1 bright); chronic pancreatitis, CF
Capsule surrounding the pancreas
autoimmune pancreatitis; capsule may demonstrate delayed enhancement
Cause of groove pancreatitis
duodenal or biliary obstruction (stenosis or stricture)
Cystic change of duodenal wall
groove pancreatitis
Large pancreatic calcifications with ductal dilation
tropical pancreatitis; younger patients, assoc. with malnutrition; increased risk of pancreatic cancer
Most common cause of pancreatic pseudocyst
acute or chronic pancreatitis (inflammatory pseudocyst)
DDx for true pancreatic cysts (non-pseudocysts)
ADPKD, VHL, CF
Atrophic pancreas with dystrophic calcifications
chronic pancreatitis, IPMN
Strongest risk factor for pancreatic adenocarcinoma
smoking
Elevated CA-19-9
pancreatic adenocarcinoma
Syndromes assoc. with increased risk of pancreatic adenocarcinoma
HNPCC, BRCA, ataxia-telangiectasia, Peutz-Jeghers
Periampullary pancreatic cancer
originates within 2 cm of major papilla; increased incidence in Gardner syndrome
Unresectable pancreatic cancer
involvement of SMA or celiac axis
Large hyperenhancing pancreatic mass with calcifications
non-functional PNET; +/- necrosis
Whipple procedure
resection of pancreatic head, adjacent duodenum, and gastric antrum => attach CBD and pancreatic remnant to distal duodenum + gastrojejunostomy
Causes of pancreatic transplant failure
acute rejection > donor splenic vein thrombosis (usually within 6 weeks); both may demonstrate reversal of diastolic flow
Shrinking pancreas transplant
chronic rejection
Santorinicele
occurs in pancreas divisum; may cause obstruction => pancreatitis
Enhancing pancreatic mass
PNET, splenule, met (RCC most commonly), serous cystadenoma
Common channel syndrome
absent septum between distal CBD and pancreatic allowing reflux
Splenomegaly size criteria
>14 cm; remember mono can cause this; volume >500 cc
Gamna-gandy bodies
splenic microhemorrhages (increased susceptibility); secondary sign of portal hypertension
Splenic hemangioma
assoc. with Kasabach-Merritt and Kllippel-Trenaunay-Weber
Splenic hamartoma
assoc. with tuberous sclerosis
Wheel within a wheel or bull’s eye appearance (spleen)
pyogenic abscess
Most common splenic mets
breast, lung, melanoma; same as adrenal gland
Tigroid spleen
normal striated appearance of spleen in the arterial phase
Wandering spleen + association
predisposed to torsion; assoc. with abnormalties of intestinal rotation
Gaucher disease
glucocerebrosidase deficiency; splenomegaly +/- multiple nodules
Multiple hypodense splenic nodules DDx
sarcoidosis, pelosis, Gaucher’s, splenic PCP
Massive splenomegaly
myelofibrosis
Peliosis
blood-filled cystic spaces in the liver and/or spleen; related to OCPs, anabolic steroids, AIDS, renal transplant, lymphoma
Most common visceral artery aneurysm
splenic artery aneurysm; most commonly in the setting of trauma or pancreatitis
Indication for splenic artery aneurysm repair
size >2 cm
Splenic infarction
sickle cell disease
Splenic vein thrombosis
may lead to gastric varices; most commonly due to pancreatitis, also diverticulitis or Crohn’s
Multiple round splenic calcifications
histoplasmosis, TB; a.k.a. “prior granulomatous disease”
Splenic abscess in a trauma or sickle cell patient
consider Salmonella
Most common cystic lesion in the spleen
pseudocyst (post-traumatic); no epithelial lining, may have mural calcifications
Felty syndrome
splenomegaly, rheumatoid arthritis, neutropenia
Epidermoid cyst (spleen)
2nd most common cystic lesion of spleen; “true” cyst (epithelial lining), may have septations
Most common benign neoplasm of the spleen
hemangioma
Littoral cell angioma (spleen)
multiple hypoattenuating lesions, hemosiderin (low T1/T2)
Malignant masses of the spleen
angiosarcoma, lymphoma, mets
Multilocular cyst with enhancing septations (spleen)
splenic lymphangioma
Cystic lesion with internal flow on US (spleen)
lymphoma; not truly cystic, but appears so on ultrasound
Benign splenic cystic lesions
true cyst (epidermoid cyst), pseudocyst, lymphangioma, intrasplenic pancreatic pseudocyst
Splenomegaly DDx
passive congestion, AIDS, lymphoma, leukemia, Gaucher’s, myelofibrosis, mononucleosis
Splenic cyst with mural calcifications
pseudocyst; true splenic cysts rarely have mural calcifications
Esophageal fold thickening
esophagitis (non-specific)
Cricopharyngeus muscle
at C5-6; border between the pharynx and cervical esophagus; UES
A ring
muscular ring
B ring
mucosal ring a.k.a. lower esophageal ring
C ring
diaphragmatic impression
Schatzki ring
narrowing of B ring (<13 mm) causing dysphagia; almost always assoc. with a hiatal hernia
Zollinger-Ellison syndrome
peptic esophagitis from increased acid from gastrin
Scleroderma (esophagus)
sphincter fibrosis => incompetence => reflux => esophagitis +/- stricture/Barrett’s/cancer
Shaggy or foamy esophagus
candidiasis; immunocompromised or motility disorders; painful
Candidiasis-like appearance in an asymptomatic elderly woman
glycogen acanthosis; painless
Large flat ulcers
CMV or HIV esophagitis
Small randomly distributed ulcers
HSV esophagitis; may have “halo of edema”
Medication esophagitis
ulcer at the arotic arch or distal esophagus (sites of narrowing)
Numerous small esophageal outpouchings
pseudodiverticulosis; dilated submucosal glands due to chronic reflux esophagitis
Long, smooth, narrow stricture
caustic, radiation induced (>50 Gy), or NGT stricture; caustic strictures assoc. with increased risk of cancer
Peptic stricture
at or just above GEJ; fibrosis may lead to esophageal shortening
Barrett stricture
mid esophageal, above metaplastic adenomatous transition (adenomatous tissue is acid-resistant)
Barrett esophagus
shown as a high stricture + hiatal hernia; precursor to adenocarcinoma
Regurgitation of fleshy mass
fibrovascular polyp (pedunculated mass usually occuring in cervical esophagus); intralesional fat
Uphill varices
seen in portal hypertension; lower half of esophagus
Downhill varices
seen in SVC obstruction; upper half of esophagus
Bird’s beak (esophagus)
achalasia (‘A’ for Auerbach’s plexus)
Corkscrew or shish-kebab esophagus
diffuse esophageal spasm
Zenker diverticulum
in the hypopharnx (above cricopharyngeus); posterior (through Killian’s dehiscence)
Killian-Jameson diverticulum
in the cervical esophagus (below cricopharyngeus); lateral, often bilateral
Dysphagia lusoria
most commonly due to aberrant right SCA
Esophageal concentric rings
eosinophilic esophagitis; Tx steroids
Fine transverse folds in lower esophagus
feline esophagus; transient, assoc. with reflux; not seen during swallowing
Most common benign mucosal lesion of esophagus
papilloma
Achalasia
increased risk of carcinoma and candidiasis; sphincter will relax eventually (vs. malignancy)
Pseudoachalasia
causes include Chagas, reflux esophagitis, prior vagotomy, malignancy; a.k.a. secondary achalasia
Fundoplication
for reflux or hiatal hernia; complications include slipping and obstruction
Esophageal cancer - stage 3 vs. 4
stage 3 = limited to adventitia; stage 4 = invasion into adjacent structures
Most common location of esophageal duplication cyst
ileum > esophagus
Traction diverticulum
triangular shape; due to TB or granulomatosis disease => mediastinal scarring; will empty
Pulsion diverticulum
round shape; due to increase intra-esophageal pressure; do not empty
Epiphrenic diverticulum vs. paraesophageal hernia
epiphrenic diverticulum occurs on the right (medial); paraesophageal hernia occurs on the left (lateral)
Esophageal web + associations
anterior impression; most commonly in cervical esophagus; increased risk of hypopharyngeal/esophageal carcinoma; assoc. with Plummer-Vinson syndrome (anemia)
Large dilated esophagus DDx
achalasia, pseudoachalasia, scleroderma
Boerhaave’s syndrome
transmural tear, typically 2-3 cm proximal to GEJ; assoc. wtih left-sided pleural effusion
Hypopharynx (boundaries)
hyoid bone to cricopharyngeus muscle
Oropharynx (boundaries)
uvula to hyoid bone
Esophageal contraction waves
primary = initiated by swallowing; secondary = initiated by food/liquid bolus; tertiary = abnormal, but not clinically significant
Umbilicated submucosal nodule (stomach)
ectopic pancreatic rest
Krukenberg tumor
GI met to ovary (gastric or colon most commonly)
Hampton line sign
benign ulcer; line of non-ulcerated acid resistant mucosa surrounding the ulcer crater
Carmen meniscus sign
malignant ulcer; splaying of large flat malignant ulcer when compression is applied; pathognomonic for gastric carcinoma
Menetrier’s disease
idiopathic rugal thickening usually involving the fundus; spares antrum
Gastric lymphoma
classically crosses the pylorus, but does not cause obstruction
Most common location for sarcoid in the GI tract
stomach
History of BilIroth II
increased risk of gastric cancer
Gardner syndrome
FAP + Desmoid tumors, Osteomas, Papillary thyroid cancer, Epidermoid cysts (“DOPE Gardner”)
Turcot syndrome
FAP + gliomas, medulloblastomas
Risk factors for gastric cancer
polycyclic hydrocarbons and nitrosamines (processed meats), atrophic gastritis, pernicious anemia, prior subtotal gastrectomy, H. pylori
Most common mesenchymal tumor of GI tract
GIST
Most common location for GIST + associations
stomach most commonly, rare before 40 y/o; assoc. with Carney’s triad and NF1
Carney’s triad
pulmonary chondroma, extra-adrenal pheochromocytoma, GIST
Virchow node
gastric met to left supraclavicular node
Sister Mary Joseph node
GI met to umbilical node
Most common extra-nodal site for NHL
stomach
Linitis plastica
scirrhous adenocarcinoma with diffuse submucosal infiltration; diffusely thickened stomach on CT
Organoaxial gastric volvulus
old ladies with paraesophageal hernias; Tx surgical repair
Mesenteroaxial gastric volvulus
peds, may cause ischemia and/or obstruction; Tx surgical repair
Gastric diverticulum
most commonly arises posteriorly from the fundus
Enlargement of the areae gastricae
H. pylori gastritis; typically in elderly patients
Multiple gastric ulcers
chronic aspirin use or ZES; if duodenal ulcers also => ZES
Roux-en-Y patient with weight gain years later
gastro-gastric fistula
Jejunogastric intussusception
occurs at the gastrojejunostomy (Roux-en-Y or Billroth); may cause gastric obstruction
H. pylori gastritis
assoc. with MALT lymphoma (low grade) and increased risk of gastric adenocarcinoma
Gastric carcinoid association
high gastrin levels (gastrinoma); carcinoid may regress after gastrinoma resection
Paradoxical increase in gastrin level after secretin administration
ZES
Hyperplastic polyp (stomach)
benign, due to chronic inflammation (gastritis)
Fundic gland polyp (stomach)
sporadic or FAP
Adenomatous polyp (stomach)
neoplastic polyp with malignant potential, especially if >2 cm; Tx polypectomy
Hamartomatous polyp (stomach)
benign; assoc. with Peutz-Jeghers, juvenile polyposis, Cronkhite-Canada, Cowden
Retrocolic Roux limb
increased risk of internal hernia
Upper limit of normal small bowel diameter
3 cm
Whirl sign (swirling mesentery)
closed loop obstruction; surgical emergency
Fossa of Landzert
mesenteric defect through which paraduodenal hernias occur; behind the 4th segment of the duodenum
Foramen of Winslow
communication between lesser sac and greater peritoneal cavity; potential space for internal hernia
Aneurysmal expansion of the small bowel
lymphoma; could also be melanoma mets or GIST (but classically lymphoma)
Rigler triad
seen with gallstone ileus; pneumobilia (from cholecystoduodenal fistula), SBO, ectopic gallstone in small bowel lumen
Cobblestone appearance on endoscopy and fluoroscopy (small bowel)
Crohn disease; result of criss-crossing ulcerations
Creeping fat
Crohn disease; fibrofatty mesenteric change seen as a result of Crohn disease
String sign
Crohn disease; segment of narrowed bowel lumen due to wall thickening in Crohn disease
Hidebound bowel
scleroderma; thin, straight bowel folds stacked together; due to fibrosis
Enteritis involving the terminal ileum
TB, yersinia, Crohn’s, campylobacter, salmonella
Whipple disease
arthralgias, increased skin pigmentation, malabsorption, abdominal pain; low density lymph nodes
Ribbon bowel
GVHD (after BMT); bowel may appear hyperenhancing
Celiac sprue associations
iron deficiency anemia, idiopathic pulmonary hemosiderosis, dermatitis herpetiformis; increased risk of small bowel lymphoma and adenocarcinoma
Infections with duodenal predilection
Giardia, Strongyloides
Sand-like nodules in jejunum
Whipple disease; with thickened mucosal folds
Sand-like nodules in jejunum and low CD4 count
MAI (pseudo-Whipple disease); with splenomegaly and retroperitoneal lymphadenopathy
Moulage pattern
Celiac disease - supposedly looks like a tube into which wax has been poured
Fold pattern reversal of jejunum and ileum
Celiac disease
Duodenal obstruction after recent weight loss
SMA syndrome
Jejunal ulcer
think ZES; especially if also ulcers in stomach and/or duodenal bulb
Cloverleaf sign
healed ulcer of the duodenal bulb
Numerous small filling defects (small bowel)
lymphoid hyperplasia
Low density mesenteric lymph nodes
TB/MAI, treated lymphoma, CMLNS (occurs in celiac sprue), Whipple disease
Jejunal diverticulosis associations
occur along mesenteric border; association with bacterial overgrowth and malabsorption
Increased risk of small bowel lymphoma
celiac disease, Crohn’s, AIDS, SLE
Most common malignant tumor of the small bowel
adenocarcinoma > carcinoid; most common benign tumor is a leiomyoma
Most common location for carcinoid
appendix > small bowel
Femoral hernia
medial to femoral vein; likely to obstruct
Littre hernia
hernia containing a Meckel diverticulum
Spigelian hernia
along the semilunar line through the transversus abdominus aponeurosis
Richter hernia
contains one wall of bowel; does not obstruct, but may strangulate
Increased risk of internal hernia after gastric bypass
laproscopic over open; extensive weight loss (less protective mesenteric fat)
Most common type of internal hernia
paraduodenal hernia (between stomach and pancreas)
Most common complication of internal hernia
closed-loop obstruction +/- strangulation
Paraduodenal hernia
small bowel between stomach and pancreas; often contains IMV and left colic artery
Small bowel met that causes intussusception
melanoma mets
Complications of celiac disease
intussusception, pneumatosis intestinalis, splenic atrophy, CMLNS; increased risk of venous thromboembolism
Typhlitis
neutropenic colitis; limited to cecum
Accordion sign
pseudomembranous colitis (C. difficile); after antibiotics
Thumbprinting
colonic edema seen on fluoroscopy; non-specific, but classically in C. diff
Collar-button ulcer
ulcerative colitis; represents mucosal ulceration undermined by submucosal extension
Lead pipe colon
ulcerative colitis; featureless and foreshortened colon
Upper limit of normal appendiceal diameter
6 mm
Cone-shaped cecum
amebiasis (spares TI), TB (involves TI)
“Fat gran and an old crone skipping down the cobblestone street away from the wreck”
Crohn’s with granulomas, creeping fat, skip lesions, cobblestoning, and rectal sparing
Ulcerative colitis associations
colon cancer, PSC, cholangiocarcinoma
Epiploic appendigitis vs. omental infarct
EA smaller and on the left; OI larger and on the right (ROI)
Appendiceal mucocele
mural calcifications; may occur with or without an associated neoplasm
Pseudomyxoma peritonei
due to rupture of an appendiceal mucocele or mucin-producing neoplasm (ovary, appendix, colon, pancreas)
Coffee bean sign
sigmoid volvulus (adults)
Cecal volvulus
young patients, points to LUQ, less common than sigmoid volvulus
Toxic megacolon
seen in UC, Crohn’s, C. diff, amebiasis, Hirschsprung’s; lack of haustral markings; colonoscopy is contraindicated
Behcet’s (GI tract)
ileocecal ulcers; look for oral/genital ulcers and pulmonary artery aneurysms
Ogilvie syndrome
a.k.a. colonic ileus or colonic pseudobstruction
Rectal cavernous hemangioma
enhancing with phleboliths (venous malformation); assoc. with Klippel-Trenaunay-Weber and blue rubber bleb syndromes
Mucous diarrhea
villous adenoma; may lead to severe fluid/electrolyte depletion (McKittrick-Wheelock syndrome)
Colonic polyp with highest risk for malignancy
adenomatous (includes villous polyps)
Rectal cancer staging
T3 = invasion beyond muscularis into mesorectal fat; indication for neoadjuvant chemoradiation
Most important sequence for rectal cancer staging
T2
Causes of ischemic colitis
acute arterial thromboembolism, chronic arterial stenosis, venous thrombosis, low-flow states
Rectal sparing
Crohn’s, ischemic colitis
Syndromes associated with adenomatous colonic polyps
FAP, HNPCC; both are AD
Indications for surgery in diverticulitis
fistula, 2 prior episodes treated conservatively
Syndromes associated with hamartomatous colonic polyps
Peutz-Jeghers (AD), Cowden syndrome (AD), Cronkhite-Canada
True mesenteries
transverse mesocolon, small bowel mesentery, sigmoid mesentery; greater and lesser omentum are not “true”
Misty mesentery
mesenteric panniculitis, but can also be seen with infiltrating neoplasm
Malignancy involving mesentery
Relatively common site of metastaseas - NHL, carcinoid (80% of GI carcinoids spread to mesentery), pancreatic, biliary, colon, breast, GIST, mesothelioma, melanoma. Primaries are less common than mets - desmoid a/w Gardner’s syndrome being one.
Sandwich sign
mesenteric lymphoma - mesenteric fat and vessles engulffed by bulky lymphomatous masses
Most common location for peritoneal carcinomatosis
retrovesicle space; natural flow of ascites dictates distribution
Barium peritonitis
inflammatory reaction => hypovolemic shock; give IV fluids
Calcified mesenteric mass
carcinoid
Upstream stenosis findings
tardus parvus waveform, RI <0.5
Downstream stenosis findings
RI >0.7
At level of stenosis findings
elevated PSV, spectral broadening
Hepatic venous waveform
above line = away from heart; below line = towards heart; A, S, and D waves
Absent hepatic venous waveform
Budd-Chiari (hepatic vein occlusion/thrombosis)
Increased hepatic vein pulsatility
right heart failure or tricuspid regurgitation (D-wave is Deeper in Drug users); both have accentuated A-wave
Decreased hepatic vein pulsatility
cirrhosis, Budd-Chiari, veno-occlusive disease, IVC thrombosis
Slow flow in the PV (number)
<16 cm/s
Causes of slow flow in the PV
portal hypertension (any cause), PV thrombosis, right heart failure, tricuspid regurgitation, Budd-Chiari
Causes of increased PV pulsatility
right heart failure, tricuspid regurgitation, HHT (from shunting), cirrhosis with arterioportal shunting
Normal PV velocity
16-40 cm/s
Obturator hernia
between obturator and pectineus muscles
Foramen of Winslow hernia
small bowel between PV and IVC
MRCP technique
fast spin echo, heavily T2-weighted
Complications of BMT (4)
PTLD, GVHD, veno-occlusive disease, typhlitis
Peritoneal inclusion cyst
h/o prior surgery or inflammatory disease; closely assoc. with an ovary; may be septated
Lymphocele (peritoneum)
h/o prior lymph node dissection or renal transplant; along pelvic sidewall
Complication of post-transplant hepatic arterial stenosis
biliary ischemia => biloma
Treatment for biliary cystadenoma
resection (risk of malignant transformation)
MR findings of confluent hepatic fibrosis
low T1, mildly T2 hyperintense, delayed enhancement; may be diffuse, focal, or ill-defined; usually in setting of cirrhosis
Hypervascular masses (liver)
HCC, FNH, adenoma, hypervascular mets, flash-filling hemangioma
Ligamentum teres
a.k.a. round ligament; runs within falciform ligament; represents obliterated umbilical vein
Small bowel polyps
Peutz-Jeghers
Multiple target lesions (small bowel)
mets (especially melanoma)
Position of GDA relative to CBD
GDA is anterior to the CBD (could be shown on US in the region of pancreatic head)
Colon cancer screening guidelines (average risk patient)
ACR/ACS recommends colonoscopy q10, flex sig q5, double contrast BE q5, or virtual colonoscopy q5; starting at age 50
Lane Hamilton syndrome
celiac disease + idiopathic pulmonary hemosiderosis
Liver window and level
W 200, L 100
Fissure separating the left and right hepatic lobes
interlobar fissure (fissure of the gallbladder)
Nodular small bowel fold thickening
Whipple disease, Crohn’s, lymphoma, infection, mets (melanoma)
Location: valeculla vs. pyriform sinuses
vallecula are above the epiglottis and pyriform sinuses
Foamy esophagus (fluoro)
achalasia, scleroderma
Glucagonoma
diabetes, dermatitis, DVT, depression, death
Increased risk of small bowel adenocarcinoma
FAP, HNPCC, Peutz-Jegher, celiac disease, Crohn’s