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Range of wt gain
Net wt gain
Recommended wt gain
11- 12. S kg
6-6.5 kg
12-5-18kg(thin) & <7kg (obese)
Extra calorie in TZ & T3
Extra calorie in lactation
+ 350kcal /day
+600kcall day
I -Ant of water retained in pregn.
2-due to
+6.5 L
Estrogen
Total Na
Total K
Total ca
Na conc
K conc
ca conc
++
++
less
less
less
less
Insulin resistance due to
max rise
HPL
Estrogen, Progesterone, cortisol
24- 28 Wks
Insulin secretion increases but there is insulin resistance
glucose transport across placenta by.
GLUT1 & GLUT-3
glycosuria
Lacturia
Proteinuria
Normal
Normal
Abnormal
Skin changes in pregn.
Linea nigra
Striae gravidarum
Chloasma gravidarum
Spider nevi
palmar erythema
Skin changes dueto
Basal body temp dueto
Breast increase due to
Estrogen
progesterone
Estrogen Progesterone Insulin PRL
Colustrum - upto
3 month
Colustrum lacks
K, Fat, carbS, vit D ,vit K
prolactin max at
pre paregn. level
pregn. level
labor
< 15 ng/ml
150 ng/ml
Estrogen effect on prolactin
Dopamine effect on prdacting.
Estrogen increases amt but decreases activity
Dopamine is PlH Prolactin inhibiting hormone
Change in vagina is K.A.
chadwick/ Jacqueimer sign
Inhabitant bacteria invagina
Dodelain bacilli (lactobacillus)
+
show
=
Protection against infection
m.C. vaginitis in pregn.
m.C.C UTI in pregn
Candidiasis.( survive in acidic media)
E. coli
Uterus wt,volume,length, shape
1.1 kg, 5 L, 35 cm. ,globular shape
mainly hypertrophy
Braxton Hicks contraction is seen in
in T2
Spleen enlarges in pregn.by
pituitary
kidney
thyroid
liver
50%
125%
Icm
Increases
remains same
THI → TH2. is absent in
PlH
Fibrinogen
Fibrin stabilizing Factor
increases
decreases.
BT, CT,Anti Thrombin Time
Unchanged
Transverse diameter increases
diaphragm pushed up by
circumference increases by
Subcostal angle
2 cm
4 cm
6 cm
103 degree
Resp. parameters
Increase
unchanged
decrease
IC TV MoVie
IRV ,EC ( IRV, RR, VC, EC)
Others
Blood O2 level
Blood co2 level
Blood pH
increases
decreases
same
vomitting due to
morning sickness and hyperemesis gravidarum common in
HCG
T1
In morning sickness suggest to have bisscuit/ water before?
Have biscuit before
morning sickness mx
Dorylamine + Pyridoxine
or Hyoscine
Hyperemesis gravidarum DX
> 5% wt loss
vitals unstable
Ketosis
more vomitting in male/ female child ?
Female child due to estrogen
m. C electrolyte abnormality in hyperemesis gravidarum ?
Hypokalaemia
M. C enzyme def in hyperemesis gravidarum?
vit k and thiamine
leads to Wernickes encephalopathy
m.C.metabolic AbN .in hyperemesis gravidarum?
metabolic alkalosis
Scoring of hyperemesis gravidarum?
Rhode, PUQE
mxof hyperemesis gravidarum
Promethazine,Prochloperazine,metochloperamide
Hydroureter move on right/left?
Right due to dextraration ofuterus
M.C. organ involved in PlH?
M. Characteristic H PE finding in PlH?
kidney
Glomerulo endothelions
UTI leads to
PTL, pyelonephritis
Serum Urea serum creatinine ,serum Uric increase/decrease in pregn.?
Decrease