COPD drug doses

Question 1

SABA
Salbutamol  (Ventolin®) MDI strength and dose

Onset: 2-5 min
Duration: 3-5 hr

Answer 1

100 mcg

2-4 puffs prn

Question 2

SABA
Salbutamol  (Ventolin®) Neb strength and dose

Onset: 2-5 min
Duration: 3-5 hr

Answer 2

1 mg/mL (other strengths avail)

2.5 mg/neb (q4-6h)

Question 3

SABA
Salbutamol  (Ventolin®) dosage forms

Answer 3

MDI
Neb
1 mg/mL (other strengths avail)
DH
PO – tablets

Question 4

SABA
Terbutaline (Bricanyl®)

Onset: 5-30 min
Duration: 3-5 hr
Slower onset than salbutamol

Answer 4

0.5 mg

500 mcg (1 puff) prn (q4- 6)

Question 5

SABA
Terbutaline (Bricanyl®)
dosage form

Answer 5

TH

Question 6

LABA
Formoterol
Oxeze®

Onset: 3-5 min
Peak: 15 min
Duration: 12 hr

Answer 6

TH
(6,12mcg)

6-12 mcg bid

Question 7

LABA
Formoterol
Floradil®®

Onset: 3-5 min
Peak: 15 min
Duration: 12 hr

Answer 7

Inh caps
12 mcg

6-12 mcg bid

Question 8

LABA
Salmeterol
(Serevent®)

Onset: 10-20 min
Duration: 12 hr

Answer 8

Diskus

50 mcg

50 mcg Bid

Question 9

LABA
Indacaterol
(Onbrez®)*

Onset: 5 min
Peak: 2-4 hr
Dur: > 24 hr

Answer 9

BH
75 mcg
75 mcg daily

Question 10

LAMA
Spiriva Tiotropium
HH

Onset: 1-3 hr
Duration: 24hr

Answer 10

18 mcg

18 mcg daily
1 cap inh

Question 11

LAMA
Spiriva Tiotropium
Respimat

Onset: 1-3 hr
Duration: 24hr

Answer 11

2.5 mcg
5 mcg ( = 2-inh once daily

Question 12

LAMA
Seebri
Glycopyrronium

Onset: 5 min
Duration :>24 hrs

Answer 12

50 mcg BH

1 inhalation (cap) daily

Question 13

LAMA
Tudorza Aclidinium

Onset: 10 min
Duration: 12 hr

Answer 13

400 mcg PI genuair

1 inhal bid

Question 14

Incruse Umeclidinium

Onset: 5-15min
Duration: 24 hrs

Answer 14

Ellipta DPI

62.5 mcg
1 inhal daily

Question 15

Combination LABA/LAMA’s

Duaklir®
Formoterol /Aclidinium

Answer 15

Genuair PI
12/400 mcg

1 inhalation BID

Question 16

Combination LABA/LAMA’s

Inspioloto
Olodaterol/Tiotropium

Answer 16

Respimat

2.5/2.5 mcg

2 inhalations once daily

Question 17

Combination LABA/LAMA’s

Ultibro®
Indacaterol/Glycopyrronium

Answer 17

BH
110/50 mcg
1 inhal (cap) once daily

Question 18

Combination LABA/LAMA’s

Anoro
Vilanterol/Umeclidinium

Answer 18

Ellipta DPI

25 mcg/62.5 mcg
1 inhal (cap) once daily

Question 19

ICS - read

Answer 19

● Zenhale® (formoterol/mometasone) 5/100, 5/200 – STEP/SA for Asthma only
● Advair 25/125 MDI, 25/250 MDI, 50/100 Diskus – STEP/SA for Asthma only
● Breo Ellipta 25/200 DPI – STEP/SA for Asthma only. Duration of action of vilanterol >24
hrs. Neither fluticasone furoate (FF) or vilanterol are approved as a separate inhaler
● Trelegy Ellipta: first triple combo therapy available – STEP/SA for COPD only

Combination ICS/LAMA/LABA
“For the long-term maintenance treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema, in patients who are not controlled on optimal dual inhaled therapy