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Asthma/COPD Exam 3 > COPD/Asthma Important Info > Flashcards

COPD/Asthma Important Info Flashcards

1
Q

what meds are inhaled corticosteroids?

A
  1. Beclomethasone (QVAR)
  2. Budesonide (pulmicort and pulmicort respules)
  3. ciclesonide (alvesco)
  4. fluticasone propionate (flovent/ armonair digihaler)
  5. fluticasone furoate (arnuity ellipta)
  6. mometasone (asmanex)
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2
Q

what meds are LABAs?

A
  1. arformoterol tartrate (brovana)
  2. formoterol (performist)
  3. indacterol (arcapta neohalar)
  4. olodaterol (striverdi respimat)
  5. salmoterol (servent)
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3
Q

what drugs are LAMAs?

A
  1. aclindinium (turdorza pressair)
  2. glycopyrrolate (seebri neohalar)
  3. revefenacin (yupelri)
  4. tiotropium (spiriva)
  5. umeclidinium (increuse ellipta)
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4
Q

what drugs are an ICS/LABA combo?

A
  1. fluticasone/ salmoterol (advair)
  2. fluticasone/ salmoterol (airduo & airduo digihaler)
  3. budesonide/ formoterol (symbicort)
  4. mometasone/ formoterol (dulera)
  5. fluticasone/ vilanterol (breo ellipta)
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5
Q

what meds are LABA/LAMA combos?

A
  1. olodaterol/ tiotropium (stiolto respimat)
  2. vilanterol/ umeclidinium (anoro ellipta)
  3. indacterol/ glycopyrronium (utibron neohalar)
  4. formoterol/ glycopyrronium (bevespi aerosphere)
  5. formoterol/ aclindinium (duaklir pressair)
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6
Q

what drugs are LABA/LAMA/ICS combo?

A
  1. fluticasone/ umeclidinium/ vilanterol (trelegy ellipta)
  2. budesonide/ glycopyrrolate/ formoterol fumarate (breztri aerosphere)
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7
Q

what meds are leuketriene modifiers?

A
  1. montelukast
  2. zafirlukast
  3. zileuton
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8
Q

what drug is an anti-IGE?

A

omalizumab

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8
Q

what med is a methylxanthine?

A

theophylline

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9
Q

what drugs are anti-IL5s?

A
  1. mepolizumab
  2. resiluzumab
  3. benralizumab
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10
Q

what drug is a anti-IL4/IL13?

A

dupilumab

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11
Q

what drug is a phosphodiesterase-4 inhibitor?

A

roflumilast

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12
Q

what do ICS drugs do?

A

prevent and control inflammation

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13
Q

what do LABAs do?

A
  1. inc. cAMP
  2. cause bronchial smooth muscle relaxation and inhibit hypersensitivity mediators from mast cells (leukotrienes and histamines)
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14
Q

what do LAMAs do?

A
  1. block the bronchoconstriction effects of acetlcholine on M3 and M2 receptors
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15
Q

what do leukotreine modifiers do?

A

block the production of leukotrienes

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16
Q

what do methylzanthines do?

A

cause bronchodilation through inhibition on PDE lll and PDE lV

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17
Q

what do anti-IgE’s do?

A
  1. inhibit IgE binding to receptors on mast cells and basophils
  2. inhibit mediator release and attenuation of early and late phase allergic response
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18
Q

what do anti-iL5s do?

A
  1. block the binding of IL-5 to the alpha chain of the IL-5 receptor complex, which results in reduced production and survival of eosinophils
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19
Q

what do phosphodiaesterase-4 inhibitors do?

A

inhibit PDE4 leading to increased cAMP

20
Q

what do anti-IL4/IL13s do?

A

blocks binding of IL4 to reduce eosinophil trafficking and IgE reactions while also blocking IL-13 to reduce mucus secretion and airway remodeling

21
Q

what drugs are COPD only (for adults specifically)?

A

LABAs (except servent), LAMAs (except spiriva respimat), LABA/LAMA combo, ICS/LABA/LAMA, and daliresp

22
Q

what drugs are used mostly for asthma?

A

leukotriene modifiers, injectables

23
Q

what do all people with asthma need?

A

an ICS

24
Q

what are the age ranges for an adult vs. a child?

A

child <12 and adult > or equal to 12

25
Q

when should you assume a medication isn’t for a child?

A
  • when it says COPD only, otherwise assume it is for a child as well we just have no data.
  • more so asthma is for children
26
Q

what meds could be given to a child (doesn’t say COPD only)?

A
  • an ICS
  • leukotriene modifers
  • Spiriva respimat
  • servent (LABA)
  • all injectables
27
Q

what are the stages of COPD?

A
  1. A
  2. B
  3. E
28
Q

what does a stage A mean ? and what would you give them?

A

a bronchodilator ( LAMA or LABA)
- mMRC ( 0 or 1
- CAT <10

29
Q

what does stage B mean? and what would you give them?

A
  • LAMA and LABA
  • mMRC > or 2
  • CAT > or 20
30
Q

what is stage E mean? and what would you give them?

A
  • they have had 2 or more exacerbations and or have been once or more hospitalized
  • LAMA and LABA
    or LAMA/ LABA. ICS ** eos > or equal to 300
31
Q

what are the stages of the GOLD standard and what is more severe?

A
  • 1 >80
  • 2 50-79
  • 3 30-49
  • 4 ( <30 FEV1 predited)
32
Q

what does the mMRC scale and how many grades?

A
  • 0-4 with o being very mild and 4 being severe
33
Q

what is a CAT assessment and what is the max score?

A
  • 40 points and it is another assessment
34
Q

can you go back on COPD? can you go back on asthma?

A
  1. COPD is progressive so no
  2. asthma yes you can go forward or back
35
Q

what types of inhalers are DPI (dry powder)?

A
  1. flexhalar
  2. aerosol
  3. DPI
  4. ellipta
  5. twisthalar
  6. neohalar
  7. diskus
  8. handihalar
  9. respiclick
  10. aerosphere
36
Q

what inhalers are mist inhalars?

A

respimat

37
Q

what inhalers are a gas?

A

HFA, redihalar

38
Q

are all inhalers MDIs?

A

yes; multiple dose inhalers

39
Q

what type of breathing does a DPI need?

A

quick and deep

40
Q

do all HFA inhalers need a spacer?

A

yes

41
Q

when would you use a LABA in asthma patients?

A

never

42
Q

what are advantaged of a DPI?

A

requires less coordination

43
Q

Which of these is an environmental risk factor for asthma?

A

A. `Allergen exposure
B. Antibiotic exposure
C. Exposures to second hand smoke

44
Q

Which symptom frequency would be classified as moderate persistent asthma?

A

A. Nighttime awakening >1 time/week

45
Q

Which patient would be considered for a COPD diagnosis?

A

> 40 year old patient with a chronic cough, dyspnea and sputum production and An adult with a history of smoking >1 pack per day for 10 years

46
Q

T/F Presence of a post bronchodilator FEV1/FVC of <0.7 confirms the presence airflow limitation consistent with COPD

A

true

47
Q

When should you consider an ICS therapy for a patient living with COPD?

A

concurrent asthma diagnosis

Asthma/COPD Exam 3 (9 decks)

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