Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CPR Pharm Exam 2 > COPD and Asthma > Flashcards

COPD and Asthma Flashcards

1
Q

List the SABA (Short-Acting Beta Agonist) (TAMPL)

A 
Albuterol 
Tetrabutline 
Metaprotenol
Pirbuterol
Levabuterol
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

List the LABA (Long-Acting Beta Agonist) (ISOF)

A 
Formoterol
Salmeterol
Indacaterol
Vilanterol 
Oldaterol
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the two drugs categories used for asthma

A

Anti Inflammatory Drugs and Bronchodilators

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Categories of drugs that fall under the Anti Inflammatory

A 
Hormone Containing (OCS and ICS)'=
Non-Hormone (Lipoxygenase inhibitors and Leukotriene Receptor Blockers )
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Categories of drugs that fall under Bronchodilators

A

Methylxanthines
Beta 2 agonists
Anticholinergics drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the primary MOA of Beta 2 agonist

A

The primary action of β2-agonists is to relax airway smooth-muscle cells of all airways, where they act as functional antagonists,
reversing and preventing contraction of airway smooth-muscle cells by all known bronchoconstrictors.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Clinical indications of Albuterol

A

Asthma
Acute Bronchitis
COPD
Bronchiolitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Adverse effects of Albuterol

A

Headache Dizziness Insomnia, dry mouth and cough

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Contraindications of Albuterol

A

Paradoxical Bronchospasm, Deterioration of Asthma, CV effects,
Immediate Hypersensitivity Reactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Only β2drug available by subcutaneous injection

A

Terbutaline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Clinical Indications for Tetrabutaline

A

treatment or prophylaxis of bronchospasm associated with asthma, bronchitis and emphysema
in patients 12 years old and older.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Warnings and Adverse Effect of Tetrabutaline

A

Not recommended as a medication for tocolysis (suppression of pre-mature labor)
Adverse Effects: headache, nausea, tachycardia and palpitations.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Clinical Indications for Metaproterenol

A

Used as a bronchodilator for bronchial asthma and for reversible bronchospasm which may occur in association with bronchitis and COPD.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Cautions and warnings associated with Metaproterenol

A
  • a significant cardiovascular effect in some patients.

- paradoxical bronchospasm(which can be life threatening).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Clinical Indications for Pirbuterol

A

Used in the prevention and reversal of bronchospasm in patients 12 years of age and older
with reversible bronchospasm including asthma. It may be used with or without
concurrent theophylline and/or corticosteroid therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Cautions and warnings associated with Pirtuberol

A

Cardiovascular: like other inhaled beta adrenergic agonists, can produce a clinically significant
cardiovascular effect in some patients, as measured by pulse rate, blood pressure and/or symptoms.

17
Q

Clinical Indications for Levabuterol

A

For the Kiddos Used in treatment or prevention of bronchospasm in patients 4 years of age and older with reversible obstructive airway disease.

18
Q

Cautions and warnings associated with Levabuterol

A

Life-threatening paradoxical bronchospasm may occur. Much like with albuterol

19
Q

Clinical Indications for Fomoterol

A

-Treatment of asthma in patients ≥5 years as an add-onto a long- term asthma control medication such as an inhaled corticosteroid.

20
Q

Drugs used for the Maintenance treatment of bronchoconstriction in patients with COPD

A

Fomoterol

Salmeterol

21
Q

Cautions and warnings associated with Fomoterol

A

In asthma, do not use without the concomitant use of a long-term asthma control medication such as an inhaled corticosteroid. Use of LABA’s, increases the risk of asthma-related deaths and asthma-related hospitalizations.

22
Q

Clinical Indication of Indacaterol and Vilanterol

A

Used to treat breathing problems caused by COPD, including chronic bronchitis and emphysema.

23
Q

A long-term, once-daily maintenance bronchodilator treatment of airflow

A

Olodaterol

24
Q

How should LABA’s be prescribed

A

LABA should be used in concomitant use of a long-term asthma control medication such as an inhaled corticosteroid.

25
Q

a muscarinic antagonist indicated for a temporary blockade of severe or life-threatening muscarinic effects.

A

Atropine

26
Q

Side Effects of Atropine

A

When the recurrent use of atropine is essential in patients with coronary artery disease, the total dose should be restricted to 2 to 3 mg to avoid the detrimental effects of atropine-induced tachycardia on myocardial oxygen demand.

27
Q

Anticholinergic Drugs that can be used for Asthma and COPD

A

Atropine
Ipratropium
Tiotropium
Aclidinium

28
Q

Actions of anticholinergic drugs in COPD

A
  • Atropine-Temporary blockade
  • Ipratropium-Maintenance
  • Tiotropium-Long-term maintenance
  • Aclidinium-Long-term maintenance
29
Q

a potent atropine analog that is poorly absorbed after aerosol administration and is therefore relatively
free of systemic atropine-like effects.

A

Ipratropium

30
Q

Clinical Use for Ipratropium

A

bronchodilator for maintenance treatment of bronchospasm

31
Q

Clinical use for Tiotropium

A
  • -An anticholinergic drug indicated for the long-term, once-daily, maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD)
    • for reducing COPD exacerbations.
32
Q

Methylxanthines (derived from the Purine Xanthine) used for Asthma and COPD

A

Theophylline
Theobromine (found in chocolate)
Caffeine

33
Q

Clinical uses of Methylxanthine

A

used in the treatment of airways obstruction caused by conditions

34
Q

Mechanism of Action of Theophylline

A
  • -Smooth muscle relaxation (bronchodilation)

- - Suppression of the response of the airways to stimuli (non-bronchodilator prophylactic effects).

35
Q

The most effective drug class for controlling asthma

A

ICS

36
Q

Drug class that reduces eosinophils in the airways and sputum, and numbers of activated T lymphocytes and surface mast cells in the airway mucosa.

A

ICS

37
Q

Mechanism of Action of Corticosteroids

A

to switch off the transcription of multiple activated genes that encode inflammatory proteins such as cytokines, chemokines, adhesion molecules, and inflammatory enzymes.

38
Q

first-line therapy for patients with persistent asthma

A

ICS

CPR Pharm Exam 2 (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions