COPD Flashcards
1
Q
What is the micro pathology of COPD?
A
- Hypertrophy and hyperplasia of mucus-secreting goblet cells of bronchial tree
- Fibrosis and thickening of bronchial walls
- Lymphocytic infiltrate
- Emphysema – Dilatation and destruction of lung tissue distal to terminal bronchiole leading to reduced elasticity and gas exchange surface
2
Q
What are the main differentials of COPD?
A
Asthma
Bronchiectasis
Lung cancer
In acute exacerbations: Pneumothorax Pneumonia Pulmonary oedema Large pleural effusion PE
