COPD Flashcards
COPD dyspnea characteristics
Progressive over time, worse with exercise, persistent
COPD chronic cough characteristics
May be intermittent and may be unproductive, with recurrent wheeze
Any pattern of chronic sputum production may indicate what disease?
COPD
What essential test is required to establish a diagnosis of COPD?
Spirometry
Post-bronchodilator FEV1 for patients with GOLD 1 COPD
Greater than or equal to 80% predicted
Spirometric Criteria for COPD
Post-bronchodilator FEV1/FVC ratio <0.70
Post-bronchodilator FEV1 for patients with GOLD 2 COPD
50 to < 80%
Post-bronchodilator FEV1 for patients with GOLD 3 COPD
30 to <50%
Post-bronchodilator FEV1 for patients with GOLD 4 COPD
<30%
mMRC Grade for patients who get breathless with strenuous exercise
Grade 0
mMRC Grade for patients who get short of breath when hurrying on the level or walking up a slight hill
Grade 1
mMRC Grade for patients who walk slower than the people of same age on level because of breathlessness
Grade 2
mMRC Grade for patients who stop for breath when walking on own pace on level
Grade 2
mMRC Grade for patients who stop for breath after walking about 100 meters
Grade 3
mMRC Grade for patients who stop for breath after a few minutes on the level
Grade 3
mMRC Grade for patients who are too breathless to leave the house
Grade 4
mMRC Grade for patients who get breathless when dressing or undressing
Grade 4
Recommended treatment for COPD in Group A
Bronchodilator
Recommended treatment for COPD Group B
LABA or LAMA
Recommended treatment for Group C COPD
LAMA
Recommended treatment for Group D COPD that are highly symptomatic
LAMA + LABA or ICS + LABA
Arterial hypoxemia PaO2 levels in normal population
PaO2 < 55 mmHg
When do you prescribe supplemental oxygen in COPD patients?
When there is arterial hypoxemia
What are the LAMA options for COPD
Tiotropium, Glycopyrronium bromide, Aclidinium
What is the dose of Tiotropium inhaler?
18mcg DPI one inhalation OD
What is the D/F of Glycopyrronium bromide?
50mcg one inhalation OD
What is the D/F of Aclidinium inhaler?
400mcg DPI one inhalation OD
Brand of Tiotropium inhaler
Spiolto
LABA + LAMA examples for COPD
Indacaterol/Glycopyrronium
D/F of Indacaterol/Glycopyrronium
110/50 mcg DPI OD
SaO2 in Arterial Hypoxemia
SaO2 < 88%
Arterial Hypoxia is still considered in PaO2 of >55 but <60mmHg in patients with what conditions?
PaO2 > 55 but <60 mmHg with right heart failure or erythrocytosis
In patients with Right Heart Failure and Erythrocytosis, what PaO2 is considered as Arterial Hypoxia?
PaO2 > 55 but <60 mmHg