COPD

Question 1

symptoms of COPD

Answer 1

breathlessness, wheezing, chronic cough, sputum production, chest tightness

Question 2

which protein when deficient increases risk of COPD

Answer 2

a1 antitrypsin

Question 3

risk factors of COPD

Answer 3

smoking, exposure to particles, chronic bronchitis, gene, infections

Question 4

when does a person gets diagnosed with COPD

Answer 4

spirometry FE1/FVC < 0.7

Question 5

according to the GOLD standard, what other things are measured?

Answer 5

mMRC, CAT and GOLD

Question 6

based on evidence, which is better: SABA/SAMA or SABA and SAMA in improving FEV1 and symptoms

Answer 6

SABA and SAMA

Question 7

based on evidence, which is correct:
LABA > LAMA or LAMA > LABA on exacerbation reduction and decrease hospitalisations

Answer 7

LAMA > LABA

Question 8

based on evidence, which is better: LABA/LAMA or LABA and LAMA in improving FEV1 and symptoms

Answer 8

LABA and LAMA (combination)

Question 9

whats the best ICS treatment for COPD?

Answer 9

LAMA+LABA+ICS

Question 10

what drugs are not recommended for prevention of exacerbations

Answer 10

statins and beta-blockers

Question 11

when is ICS usually added

Answer 11

when eos >300 or 100-300
no pneumonia events
hx of mycobacterial infections

Question 12

other diseases exacerbating COPD

Answer 12

pneumonia, PE, HF

Question 13

what are some non-pharmacologic management of COPD

Answer 13

smoking cessation, pulmonary rehabilitation, vaccinations (flu, pneumococcal, covid-19, tdap (if not done), zoster (>50yrs))