COPD Flashcards
is a preventable and treatable slowly progressive respiratory disease of airflow obstruction involving the airways, pulmonary parenchyma, or both.
COPD
Includes any form of lung tissue, including bronchioles, bronchi, blood vessels, interstitium, and alveoli
Parenchyma
T/F The airflow limitation or obstruction in COPD is fully reversible
F (not fully reversible)
The two distinct disease process
Emphysema and Chronic Bronchitis
An inflammatory response occurs throughout
Proximal and peripheral airways, lung parenchyma, pulmonary vasculature.
Proximal airway
Trachea and bronchi greater than 2 mm in diameter
Peripheral airway
Bronchioles less than 2 mm diameter.
Disease of the airways, defined as the presence of cough and sputum production for at least 3 months in each of 2 consecutive years.
Chronic Bronchitis
Impaired oxygen and carbon dioxide exchange results from destruction of the walls of overdistended alveoli.
Emphysema
Abnormal distention of the airspaces beyond the terminal bronchioles and destruction of the walls of the alveoli.
Emphysema
One of the complications of emphysema
right sided heart failure brought on by long term high blood pressure in the pulmonary arteries.
Two main types of emphysema
Panlobular (Panacinar) and Centrilobular (centroacinar)
Destruction of the respiratory bronchiole, alveolar duct, and alveolus.
Panlobular (Panacinar)
Risk Factors for COPD
-Environmental exposures
-Host factors
-Smoking
Environmental risk factors
-Smoking
-marijuana
-Secondhand smoke
-prolonged and intense exposure to occupational dusts and chemicals
-indoor air pollution
-outdoor air pollution