COPD Flashcards
Chronic Obstructive Pulmonary Disease (COPD)?
refers to a group of diseases that cause airflow blockage and breathing-related problems. It includes emphysema and chronic bronchitis.
Emphysema
destruction of the alveoli
Chronic bronchitis
presence of chronic productive cough for 3 months in 2 successive years
Do people w COPD only show emphysema or chronic bronchitis?
People with COPD often display characteristics of both chronic bronchitis and emphysema.
How common is COPD in Canada?
prevalence of COPD among the population aged 35 years and older was 9.4% (2 million Canadians).
What causes COPD ?
- exposure to irritants that damage your lungs and airways
- Tobacco smoking
Pathophysiology of COPD
Noxious particles and Gases causes:
inflammation of central airways/ peripheral airway remodelling/ parenchymal destruction/ pulmonary vascular changes
Causes:
COPD- mucus hypersecretion/ cilia dysfunction/ airflow limitation/ hyperinflation of lungs/ alveolar destruction/ loss of elastic recoil/ gas exchange abnormalities/ pulmonary hypertension/ cor pulmonale/ systemic effects
Bullae
cystic space >1cm in diameter
Bleb
cystic space <1cm in diameter
Why do people w COPD have pulmonary hypertension?
hypoxia leads to pulmonary vasoconstriction leading to an increase in pressure, therefore leading to pulmonary hypertension
What systemic (extrapulmonary) changes can result from COPD?
unintentional weight loss, skeletal muscle dysfunction, an increased risk of cardiovascular disease, osteoporosis, and depression, among others.
What are the clinical manifestations (signs and symptoms) of COPD?
- dyspnea
- intermittent cough in the morning
- productive cough during winter
- Barrel Chest
What position to patients sit in to relieve symptoms of COPD?
Leaning forward
Why might polycythemia develop later in the development of COPD?
Polycythemia develops as a result of increased production of red blood cells secondary to the body’s attempt to compensate for chronic hypoxemia.
Usual COPD age at onset
> 40 yrs
Usual Asthma age at onset
<40 yrs
Smoking history, COPD vs Asthma
COPD: usually >10 packs/ year
Asthma: Not casual but could become trigger
Which produces sputum, Asthma or COPD?
COPD frequently
Asthma infrequently
Do asthma spirometer findings improve or normalize? What about COPD?
Asthma: Findings often normalize
COPD: Findings sometimes improve but never normalize
Is asthma progressive?
Usually stable with exerbations
is COPD progressive?
Progressive worsening with exacerbations
How are PFT’s conducted?
conducted to measure lung volumes and airflow. -
In PFTs, a spirometer is used. The patient’s age, sex, height, and weight are entered into the PFT computer to calculate predicted values.
The patient inserts a mouthpiece, takes as deep a breath as possible, and exhales as hard, fast, and long as possible.
The computer determines the actual value achieved, predicted (normal) value, and percentage of the predicted value for each test.
Normal PFT
A normal actual value is 80 to 120% of the predicted value
Forced vital capacity (FVC)?
Amount of air that can be quickly and forcefully exhaled after maximum inspiration. Normal: >80% of predicted