controlled substances Flashcards

1
Q

controlled substance

A

a drug which has been declared by federal or state law to be illegal for sale or use, but may be dispensed under a physician’s prescription
bases for control and regulation is danger of addiction abuse physical and mental harm, including death, trafficking by illegal means, and the dangers from actions of those who have used the substances

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2
Q

controlled substances act of 1970

A

five categories

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3
Q

schedule I

A

no currently accepted medical use in US, lack of accepted safety for use under medical supervision and a high potential for abuse
heroin, LSD, marijuana

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4
Q

schedule II

A

high potential for abuse which may lead to severe psychological or physical dependence
opium, codeine, oxycodone

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5
Q

schedule III

A

potential for abuse less than substances in schedule I or II and abuse may lead to moderate or low physical dependence or high psychological dependence
buprenorphine, codeine w/tylenol

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6
Q

schedule IV

A

low potential for abuse relative to substances in schedule III
alprazolam, carisoprodol

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7
Q

schedule V

A

low potential for abuse relative to schedule IV and consist primarily of preparations containing limited quantities of certain narcotics

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8
Q

amphetamine and methamphetamine

A

schedule II stimulant
first medical product for head colds
prescription in 1951
2009 DEA estimated mexican cartels controlled 80% all meth in US

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9
Q

manufacturing meth

A

three ways
red P
nazi method
one pot shake n bake

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10
Q

red p

A

pseudo tablets
red phosphorous
iodine
Hydrogen peroxide
solvent
strong base
HCl gas or sulfuric acid
tablet pull, red P + iodine + pseudo + water, base then solvent, salting out, icing
icing is last step, last stage of processing
trying to make pdt look pretty
ingredients: water, acetone, cutting agent

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11
Q

nazi method

A

tablets, ammonia anhydrous, lithium, water, solvent, HCl

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12
Q

one pot shake n bake

A

tablets, ammonium nitrate or fertilizer, strong base, solvent, lithium, water

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13
Q

dangers of meth lab

A

harsh chemicals
sodium hydroxide, lithium, phosphine gas, solvent toxicity, white phosphorous (looks like meth but actual explosive)
vapors at icing lab
closed refrigerator and light bulb
one pot: explosion
TATP (triacetate triperoxide)
hydrogen peroxide, sulfuric acid, acetone, organic solvent
looks like meth

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14
Q

winning the war on drugs?

A

combat methamphetamine act 2005
OTC meds contain gin ehh/pseudo restricted behind counter
daily and monthly purchase limits
form of identification
comprehensive meth control act 1996
alternate chemicals in OTC drugs, phenylephrine
alternate processes P2P

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15
Q

side notes for meth

A

meth mouth, salivary flow reduction
saliva flushes away bacteria
meth users might be soda junkies too
bruxism, teeth grinding
smuggling
soaked cards/letters, big rig axles, unlimited ways of bringing It in

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16
Q

heroin

A

schedule I, narcotic analgesic

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17
Q

history heroin

A

opium used for medicinal purposes by assyrians
1803 isolation of morphine
1800s opium used to treat diarrhea and suppress tuberculosis coughs
1974, synthesis of heroin

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18
Q

opiates vs opioids

A

opiates are natural opiods
opioids are all natural, semi-synthetic, and man made

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19
Q

production of heroin

A

specific poppy
papaver somniferum
Afghanistan Myanmar and mexico

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20
Q

heroin synthesis

A

extract raw opium from poppy
dissolve in water and add lime
calcium morphenate
add ammonium chloride or ethyl acetate
morphine base
add acetic anhydride and Na2CO3
heroin base
dissolve in ethyl enter for black tar heroin
add HCL for brown heroin
dissolve in ethyl ether add HCL and EtOH for white heroin

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21
Q

production

A

injectable heroin includes acetic acid, vinegar
black tar heroin is made in mexico
cutting agents are APAP, caffeine, lactose, mannitol, procaine, starch, diphenhydramine, and possibly other drugs

22
Q

side notes for heroin

A

usage
injection, needle sharing or reusing needles, chasing the dragon
combo drugs
speedball , stimulant
cheese, Tylenol PM
withdrawals
anxiety problems
alprazolam, new market!
counterfeit tablets

23
Q

fentanyl

A

schedule II
synthetic opiod
narcotic analgesic

24
Q

history of fentanyl

A

1960 developed by Janssen pharm
1970s medical personnel abuse
other similar structures
alpha-methylfentanyl
carfentanil
medicinal use, patches, lollipops, buccal soluble films

25
fentanyl safety
carfentanil, OD is 20 micrograms a grain of salt is 50 micrograms LD50 is 2 mg first responders have CPR risk lab personnel have inhalation risk narcan
26
phencyclidine , PCP
schedule II dissociative anesthetic psychological drug
27
pcp history
1957 parke davis manufacturered sernyl 1965 taken off market, bad side effects 1967, sernylan for animals late 1970s, all legal maufacturering stopped now pop is only made via clandestine labs
28
pcp manufacturing
bucket 1: piperidine, water, sodium cyanide bucket 2: sodium metabisulfate, cyclohexane, water bucket 1 and 2 make PCC Grignard reagent: magnesium turnings, ether, bromobenzene pcc nad Grignard reagent make PCP
29
safety first and side notes pcp
cyanide solvents: bromobenzene cyclohexane ether magnesium turnings are water reactive, similar to Li, but not as bad PCP is made during the summer TCP Is an analog of PCP
30
cocaine
schedule II stimulant
31
cocaine history
andes mountains 1884 Local anesthetic 1860 first used by amber nieman 1890s US workers Coca-cola Colombia, peru, bolivia cocaine found naturally in the coca plant
32
manufacturing cocaine
coca leaves plus alkali stuff plus water, add kerosene, leaves and water thrown out add acid and alkaline stuff, paste is formed add acid and water to paste add oxidizer to get rid of impurities keep only liquid solution cocaine in base form cocaine base plus acetone add acid cocaine salt cocaine salt plus water add baking soda heat, remove excess liquid crack cocaine crack is schedule I drug
33
safety and side notes cocaine
cocaine labs not typical for US chemicals include acids and bases but it is a white powder cutting agents: APAP, caffeine, lactose, levamisole, lidocaine, quinine used to dilute/change drugs with something less expensie contaminants, adulterants, diluents, by-products pharmacologically active ing give either synergistic/antagonistic effects
34
marijuana
cannabis sativa schedule I variable psychophysical actions, effects range from relaxing intoxication to anxiety and panic attacks
35
history marijuana
used as early as 3000 BC medicinally as an anesthetic attentive enhancer and for constipation introduced to n America by settlers in 1600s predominantly used fo hemp fiber to make rope and clothing mid 1800s pharaceutical companies begin marketing marijuana containing products marijuana tax of 1937 made possession or transfer for marijuana illegal except medical or industrial uses, which were heavily taxed controlled substances act of 1970 repealed tax act and now? CA adult use of marijuana act, recreational use since 2016
36
butane honey oil
manufacturing: blasting tube lots of butane very flammable
37
marijuana and its chemical components
delta-9-tetryhydrocannabiniol (THC) main psychoactive ingredient somewhat polar BP: 315 F solubility in water, about 10 mg per gallon terpenes and terpenoids produced by most plants name comes from turpentine very non-polar (like oil) proteins, sugars, hydrocarbons, fatty acids, amino acids none of these are desired products in concentrated cannabis we only want THC and terpenes terpenes have no psychoactive effects, fragrance (aromatic) chemicals, hash taste
38
review of polarity in solvents
like dissolves like water is polar and ionic sugars salts, acids, all things we don't want alcohol is polar and covalent dissolves other polar covalent compounds sugars, terpenes, other alcohols, cannabinoids things we do want in hash butane is non-polar covalent dissolves terpenes, hydrocarbons, cannabinoids, things we do want in hash
39
problems with solvents used
butane and alcohol are most common volatile organic compounds evaporate faster than water flammable
40
chem properties
flammable chemicals have a point at which enough of the chemical exists in the air that it will ignite in the presence of an ignition source lower explosive limit just to clarify there is also an upper explosive limit, UEL not typically encountered
41
breakdown of butane
LEL:1.8% when air next to ignition source (stove, smoking cigarette guy) has 1.8% butane, it will cause a flash fire/explosion when liquid butane evaporates to become a gas, it expands about 230 times, one 12 oz can becomes 2760 ounces (21 1/2 gallons) of pure butane gass since only 1.8% of air needs butane, you can see it doesn't take much to get a room or garage to LEL
42
breakdown of ethanol
LEL: 3.3% evaporates, expands 850 times. One 12 ox bottle of ever clear, (151 proof, 75.5% ethanol) becomes 7700 ounces about 96 gallons of pure gas
43
one more possibility
supercritical fluid extraction compresses carbon dioxide to high enough pressures that it becomes liquid CO2 is not flammable huge pressure is still a danger
44
chemical structures
polarity of solvent matters butane and ethanol are best water is not effective volatility of solvent is important good: for users, extracts THC with decent efficiency and evaporates quickly leaving concentrated cannabis bad: flammable, explosive mixtures in air ugly: for first responders same vapors that already ignited can build up again and re-ignite
45
crime lab testing
every person who manufactures compounds converts produces derives processes prepares either directly or indirectly by chem extraction or independently by means of chem synthesis any controlled substance shall be punished unless otherwise provided by law
46
criminalists point of view
what we need to form a scientific opinion of BHO lab extraction tube, apparatus that shows processing source material, marijuana, ideally from tube filter or screen, one from tube is best finished product, collected from filter/screen or from pyrex type baking dish or silicone mat indication of solvents used, butane or alcohol
47
safety first
false sense of security BHO extraction may seem simple, but these chemicals can and DO cause property damage and severe burns not considered as other controlled substances, just marijuana do not simply handle extraction tube similarities b/n BHO tubes and pipe bombs
48
other drugs
MDMA, LSD< GHB, steroids, synthetic cathinones, synthetic cannabinoids, DMT, ketamine, peyote
49
presumptive tests
color crystals logo ID
50
confirmatory tests
FTIR, GC/MS, Raman