Control Of The Digestive System Flashcards

1
Q

Where is the cephalic phase?

A

The head

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2
Q

Where is the Gastric phase?

A

Stomach

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3
Q

Where is the intestinal phase?

A

The intestine

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4
Q

The cephalic phase:

A
  • triggered by sight, smell, taste, thought, chewing or swallowing food
  • saliva is secreted
  • stomach, pancreatic and liver secretions happen
  • gastric contractions
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5
Q
A
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6
Q

The gastric phase:

A
  • triggered by presence of food in the stomach
  • distension
  • peptide fragments, caffeine & alcohol present
  • increased gastric motility
  • gastric juice is produced
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7
Q

The intestinal phase:

A
  • triggered by presence of food in the duodenum
  • distension
  • chemical composition of food
  • pancreas secretes bicarbonate into the duodenum
  • pancreas secretes digestive enzymes into the duodenum
  • gallbladder releases bile into the duodenum
  • segmentation contractions of the small intestine happen
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8
Q

External stimuli that activate regulatory factors:

A
  • cephalic factors
  • emotion
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9
Q

Local stimuli within the gastrointestinal tract that activate regulatory factors:

A
  • stretch or distension of the gastrointestinal tract wall
  • chemical components of the lumen
  • osmolarity of the contents in the lumen
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10
Q

What does stretching / distension of the gastrointestinal tract wall do?

A
  • stimulates mechanoreceptors
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11
Q

What do chemical components in the lumen do?

A

Stimulate chemoreceptors

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12
Q

What does the osmolarity of the contents in the lumen do?

A
  • stimulates osmoreceptors
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13
Q

Regulatory factors activated to regulate motility and secretion:

A
  • intrinsic nerve plexuse
  • extrinsic nerves
  • gastrointestinal hormones
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14
Q
  1. Intrinsic nerve plexuses
A
  • submucosal plexus & Myenteric plexus = are in the gastrointestinal tract wall and run its entire length

Responsible for short reflexes = influence motility or secretion in response to specific local stimuli

  • stimulation of a receptor in one area of the tract, neurally influences activity of another region in the tract
  • this provides a mechanism for self regulation of the tract & helps to coordinate activity of organs within
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15
Q

Small volume for =

A

Weaker contractions

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16
Q

Larger volumes for =

A

Stronger contractions

17
Q

Do lipid rich meals have a longer or shorter digestion time?

18
Q

Do carbohydrate rich meals have a longer or shorter digestion time?

19
Q
  1. Extrinsic nerves, what are they?
A
  • nerve fibres from both branches of the autonomic nervous system
  • sympathetic & parasympathetic nerves
20
Q

Why do extrinsic nerves have long reflexes?

A
  • involves long pathways between the central nervous system and the digestive system
21
Q

Where do the extrinsic nerves start and what do they respond to?

A

Originate = outside the digestive system
Respond to = cephalic factors & emotion

22
Q

How to extrinsic nerves influence gastrointestinal tract motility and secretion?

A
  • modifies ongoing activity in the intrinsic plexus
  • alters the level of gastrointestinal hormones secretion
  • acts directly on the smooth muscle and glands
23
Q

What do parasympathetic nerves increase?

A
  • gastrointestinal tract motility
  • secretion of digestive enzymes
  • secretions of gastrointestinal hormones
24
Q

What do sympathetic nerves do to these factors?

A
  • decrease them
25
3. What are gastrointestinal hormones?
- peptides produced by specialised endocrine cells in the gastrointestinal mucosa - triggered by local changes in the digestive tract, or short / long reflexes
26
What do they exert excitatory of inhibitory influences on?
- carried through blood to other areas of the gastrointestinal tract - smooth muscles and exocrine gland cells
27
What are the three families of gastrointestinal hormones?
- gastrin family - secretin family - no family
28
What are a part of the gastrin family?
- gastrin - cck - variants
29
Gastrin: what is it?
- secreted by pyloric g cells - stimulated by the presence of protein in the stomach
30
What is the function of gastrin?
- increased hydrochloric acid and pepsinogen secretion - increases gastric motility - relaxes ileocecal sphincter - induces mass movement - increases growth of small intestinal mucosa
31
Cck - cholecystokinin - what is it?
- secreted by i cells in the duodenum & jejunum - stimulated by the presence of fat & protein in the duodenum
32
What is the function of cck?
- contracts the gallbladder, relaxes sphincter of oddi - increases intestinal motility & pancreatic enzyme secretion - decreases gastric motility & secretion
33
Secretin - what is it?
- secreted by s cells in the duodenum - stimulated by acid in the duodenum
34
What is the function of secretin?
- decreases gastric emptying - decreases gastric secretion - increases NaHCO3 secretion, by the pancreas & liver
35
A part of the secretin family - glucose-dependent insulinotropic peptide - gip:
- secreted by duodenal & jejunum cells - stimulated by the presence of glucose in the duodenum
36
What is the function of GIP?
- increases insulin - decreases gastric emptying & acid secretion
37
What is motilin?
- final family - secreted by duodenal & jejunum cells - between meals
38
What is the function of motilin?
- increases the migrating motility complex