Control Of Gene Expression Flashcards
How the lac operon is transcribe?
As a single mRNA
What it the function of the repressor?
To bind to the operator and prevent transcription
What is the function of the activator?
Bond to the promoter site and increase transcription
What is the function of inducers?
Small molecules in the cell environment that activate or repress transcription
What is the role of positive control of the lac operon?
Turns the genes on and activates them
What is catabolite activator protein (CAP)?
A protein that binds to the promoters of opérons
*Stabilize the binding of RNA polymerase to the promoter region and increases transcription
What a low glucose means?
That the lac operon transcribes more frequently and lactose is metabolise
*ATP is low — CAMP is high — RNA pol binds to the lac promoter more strongly
When glucose is hight what happens?
ATP is high — CAMP is low — RNA pol binds less strongly
CAMP is used to make what?
ATP
What is the negative control of prokaryotic regulation?
When the repressor protein sticks onto the operator and block RNA polymerase to
What happens to the negative control if lactose is high?
Some of allolactose sticks onto the repressor — can then no longer bind to the operator — proceed with transcription
What VNTR means?
Repeated sets of nucleotides present in DNA’s non-coding regions
What SNP stands for?
Variation in a single nucleotide
how can polymorphisms can be used to distinguish between individuals?
Since they are highly diverse across populations and individuals genetic patterns unique to each person
