Control of arterial pressure 2 Flashcards
ecf
plasma vol + interstitial fluid volume
what hapens if plasma voluem falls
compensatory mechanisms shifts fluid form the intersttiial comprtment to the plasma comprtment
what affects extracellular fluid volume
water excess or deficit
na excess or deficit
role of hormones
act as effectors to regulate the extracellular fluid volume and plasma by regulating water and salt balance
hormones which regulate ecfv
RAAS
NPs
ADH
role of renin
released from kidneys and stimulates the formation of angiotensin 1 in the blood from angiotensinogen produced by the liver
what is angiotensinogen produced by
liver
where is renin released from
kidneys
ACE role
converts angiotensin 1 to angiotensin 2
function of angiotensin 2
stimulates the release of aldosterone from adrenal cortex
and causes systemic vasoconstriction; incraesees svr
role of aldosterone
acts on kidneys to increase sodium and water rentention; increases plasma volume
effect of angiotensin 2
increased svr and bp
increased ads and plasma volume
increases thirst
natriuretic peptides
peptide hromones synthesised by heart
when are nps released
in response to cardiac distension or neurohormonal stimuli
what do nps cause
excretion of salt and water in the kidneys therby reducing blood volume and bp
decraeses renin release ; decraese bp
act as vasodilatoirs
counter reg system for raas