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Pharm II TBL > Contraceptive TBL > Flashcards

Contraceptive TBL Flashcards

1
Q

Best IUD for nulliparous women

A

Skyla (smallest)

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2
Q

Paragard FDA approved for how long?

Effective for how long?

A

FDA: 10y
effective: up to 20y

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3
Q

Mirena FDA approved for how long?

Effective for how long?

A

FDA: 5y
effective: 7y

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4
Q

Skyla FDA app for how long?

A

3y

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5
Q

Liletta FDA app for how long?

A

3y

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6
Q

Hormone in hormonal IUD?

A

levonorgestrel

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7
Q

IUD to tx heavy menstrual bleeding

A

Mirena

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8
Q

AEs for hormonal IUD

A

uterine perf
irregular/inc bleeding 1st 3-6mo
infection w/ insertion
ovarian cyst

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9
Q

AE for copper IUD

A

heavy bleeding/cramping
uterine perf
infection
ovarian cyst

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10
Q

What is Essure?

A

Device placed in FP to cause occlusion (sterilization)

  • device in fallopian tubes
  • use another BC for 1st 3mo
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11
Q

Nexplanon active ingredient

A

progestin etonogestrel

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12
Q

(most) OCP ingredients

A

ethinyl estradiol, progestin (less progestin)

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13
Q

which has a lower total hormone dose per cycle - monophasic or multiphasic pills?

A

multiphasic

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14
Q

which has less bleeding effects/AEs - mono or multi phasic pills?

A

SAME for both

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15
Q

how many periods/year on a 21/7 pill pack?

A

13

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16
Q

advantage of extended cycle contraceptives?

A
  • fewer menstrual sx (HA, blot, pain)
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17
Q

non-contraceptive benefits of pills

A
  • dec risk ovarian + endometrial Ca
  • less dysmenorrhea
  • dec. ectopic pg
  • dec. benign breast dz
  • dec. free T (less acne/hirsutism)
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18
Q

what type of BC to tx PCOS?

A

OCP combo pills

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19
Q

desogestrel and orgestimate are types of ….

A

progestins (claim to have less androgen activity than previous progestins)

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20
Q

AEs of combo OCP w/ higher estrogen

A
  • breast tenderness
  • breast enlargement
  • if very high (>50mcg)… increased MI, ischemic stroke (CI in unctrolled HTN/smokers)
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21
Q

AEs of combo OCP w/ lower estrogen

A
  • bleeding disturbance

- VTE

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22
Q

AEs of extended cycle OCP

A

spotting

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23
Q

estrogen-containing OCP CI in ___

A 
>15 cigs/day
>35 yo w/ HTN, CHD, HF, CVA, DM w/ end-organ damage, migraines, @ risk for VTE)
Hx breast Ca
Hx thromboembolic d/o
Hx liver dz
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24
Q

Indication for minipill

A
  • BF women
  • estrogen CI women
  • if estrogen poorly tolerated
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25
Q

Drugs that dec effectiveness of OCPs

A
  • rifampin
  • HIV antivirals
  • anticonvulsants
  • St John wrost
  • pcn/tetracycline - unproven
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26
Q

Active ingredient of injectables

A

medroxyprogesterone

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27
Q

AE injectables

A

wt gain
amenorrhea/irreg bleeding
dec boen mineral density

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28
Q

How soon can you get pg after last injection?

A

6-12 mo (median 10 mo)

29
Q

Patch active ingredients

A

ethinyl estradiol + norelegestromin

30
Q

Patch less effective in women weighing >

A

90kg

31
Q

Patch AE

A

skin irritation, breakthru bleeding

32
Q

Who gets a higher dose of hormones - those on patch or pill?

A

patch

33
Q

How to use patch?

A

3 weeks on/1 off

arm, butt, back, low abd

34
Q

active ingredient vaginal ring

A

ethinyl estradiol + etonogestrel

e-tono - tone - ringtone

35
Q

how long can you take the ring out w/o needing back up contraception

A

3h

36
Q

how long to use backup contraception after leaving the ring out for >3h

A

7d

37
Q

AE ring

A

discomfort
HA
vaginal discharge

38
Q

which has more nausea, dpn, acne, irritiability- ring or OCP?

A

OCP

39
Q

what % of pg can emergency contraception prevent?

A

50-80%

40
Q

Plan B one step, Next Choice One Dose are what type of ECP?

A

progestin only

active ingredient: levonorogestrel

41
Q

progestin only ECP effective for

A

72h (possible up to 5d)

42
Q

ECP SE

A

HA
abd pain
breast tenderness
N/V

43
Q

Ella is a

A

antiprogestin ECP

active ingred: ulipristal acetate

44
Q

Ella effective for

A

5d

45
Q

Most effective ECP?

A

Ella

46
Q

1st line ECP for overwt/obese

A

Ella

47
Q

Copper IUD works as ECP for up to how long after conception

A

5d

48
Q

If you vomit __h after taking ECP you need another dose

A

<1h

49
Q

When to put diaphragm in

A

6h before sex, til 6h after

50
Q

Max time to have the diaphragm in

A

24h

51
Q

Max time to have cervial cap in

A

48h

52
Q

How to use spermicide w/ the cap/diaphragm

A
  • once before sex w cap

- before each act of intercourse w/ diaphragm

53
Q

What kind of condom doesnt protect against viral infection

A

lamb intestine

54
Q

What kind of condom is most likely to break

A

polyurethane

55
Q

What kind of condom may be most effective at preventing STI and can be used w/ oil based lube

A

female condom

56
Q

How long is the sponge effective after you put it in and leave it there

A

24h

57
Q

Max time to leave in sponge to avoid infection

A

24-30h

58
Q

What area of anatomy does spermicide have to be in contact w/

A

cervix

59
Q

how long before sex to use spermicide

A

1h

60
Q

which devices require no compliance by woman, and thus most effective

A

implant, IUD, sterilization

61
Q

most cost effective

A

implant/IUD

62
Q

most effective emergency contraceptive

A

copper IUD

63
Q

Which binds least strongly to estrogen receptor ?

A

E3 (estrone/estriol)

64
Q

where is estrogen produced before ovulation

A

follicle by theca + granulosa cells

65
Q

where is estrogen produced after ovulation

A

LUTENIZED granulosa +theca cells of coprus luteum

66
Q

Aromatase (CYP19A1) does what 2 conversions?

A

androstenedione > estrone

testosterone > 17Bestradiol

67
Q

what does estrogen do to your lipid profile?

A

^HDL + triglycerdies

dec LDL and cholesterol

68
Q

what does estrogen do to your blood coag factors?

A

^ Factor 2, 7, 9, 10, plasminogen

decr antithrombin 3

Pharm II TBL (1 decks)

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