Contraceptive Methods Flashcards
What are the 3 different aspects to contraception?
- social issues
- biological issues
- moral issues
What % of U.S. pregnancies are unintended?
60%
** What is the pearl index?
- the number of failures per 100 women-years of exposure. (SEE WRITTEN CARD for EQUATION).
When a patient asks for contraception, what 2 general options will you tell them?
- hormonal
2. non-hormonal
What are the types of hormonal contraceptive methods?
- BC pills
- transdermal or intravaginal
- implantable device
- hormonal injections
- anti-progesterones, male hormonal methods, and vaccines (experimental).
What are the most commonly used combined low dose BC pill?
- 20-50 ug of estrogen (usually ethinyl estradiol + a progestin)= suppress pituitary release of LH and FSH (gonadotropins). Progestin is the more effective ovulation inhibitor bc this is what is produced when you are pregnant to prevent ovulation (aka we fool the brain). Progestin also causes changes in cervical mucus and endometrium, hindering sperm transport and embryo implantation.
What types of combo pills exist?
- monophasic= constant does of hormones
- multiphasic= varying doses of hormones.
What changed from the 1st generation combo pills to the 3rd generation combo pills?
lower androgenic effects :)
- Norgestrel and Levonorgestrel= HIGH androgens.
- Ethynodiol, Norgestimate, Desogestrel= LOW androgens.
What is the “user” failure rate for combined low dose BC pills for the first year of use?
8% (since most women do not take them perfectly).
Will fertility return soon after discontinuation of combo low does BC pills?
YES :)
Are the side-effects with low dose combo-BC pills bad?
No they aren’t bad.
What are the options to relay to the pt about when to start their pill?
- SUNDAY start= at the end of the month you will get your period in the middle of the week.
- SAME DAY start= start in sync with their cycle. This is designed to decrease break-through bleeding.
- QUICK start= start today in the office and do this every single day at this time.
What are the non-contraceptive benefits of taking a combined low dose BC pill?
- helps menstrual cycle disorders, acne, hirsutism, bleeding due to leiomyomas, pelvic pain due to endometriosis, decreases risk of endometrial cancer, decreases risk of ovarian cancer, and decreases risk of colon cancer! :)
What are the contraindications for combined low dose BC pills?
- older than 35 and smoking more than 15 cigarettes per day.
- UNCONTROLLED HTN (systolic 160 or diastolic 100). Once treated they can go on BC.
- VTE
- ischemic heart disease
- hx of stroke
- valvular heart disease
- SLE ?
- migraine with AURA (lose vision or lose sensation somewhere in your body).
- cirrhosis
- breast cancer
What are some side effects of combined low dose BC pills?
nausea (19%), breast tenderness, headache, leg cramps, weight gain, mood changes, or decreased libido.
*most of these will ameliorate over the course of 6 cycles.
What is the Nuvaring?
- transvaginal ring
- same as BC pill only very low dose and does not have 1st past metabolism bc it goes directly into the blood stream.
What are some advantages to the Nuvaring?
- do not have to remember to take the pill.
- cycle flexibility bc the ring has 5 weeks of therapy in every ring (meaning that if you wanted to leave it in for the 4th week instead of taking it out to allow for your normal cycle, you could).
- local estrogen for vaginal dryness in perimenopause
- lower rate of side effects
What is the contraceptive patch, Ortho Evra?
- path placed on skin weekly x 3, then left off for a week for withdraw bleed.
What are the disadvantages of the Ortho Evra patch?
- it is hard to hide and people will see it.
- high rate of variability in absorption that allow for high estrogen levels.
- 2 fold increase in non-fatal VTE
Who are candidates for progestin-only contraceptives?
- women with CV risk factors, DM, lipid disorders, estrogen related side effects, migraine headaches, or are post-partum or breast feeding.
- these are for longer term use.
What are the most common side effects of progestin-only contraceptives?
- irregular bleeding and spotting
Do progestin0only contraceptives need to be taken continuously?
YES. There is NO hormone-free interval.
What happens if you delay more than 3 hours with progestin-only contraceptives?
requires back-up contraception for 48 hours.
What did a subgroup analysis confirm in regards to association between VTE risk and progestin-only PILLS or a progestin IUD?
- there was no association
* HOWEVER, there was an increased risk for users of an INJECTABLE progestin like depo provera.
What is Depo Provera (Depot Medroxyprogesterone Acetate; DPMA)?
- progestin-only IM injection given every 3 months.
- has been around for a long time.