Contraception Flashcards
What is the most accepted MoA of levonorgestrel?
Levonorgestrel most accepted mechanism is that it delays ovulation.
It also interferes with corpus luteum function, thicken cervical mucous making it more difficult for sperm to get through, alter tubal transport of sperm, egg or embryo and directly inhibits fertilisation-clinical evidence is lacking.
Important features to remember when giving levonorgestrel
If a person vomited the morning after pill within 2 hours, then another pill is needed.
The morning after pill might also cause an irregularity in the cycle.
If the next period is light or more than 3 days late, she’d need a pregnancy test.
What are other options for emergency contraception?
Copper coil IUD
EllaOne (Ulipristal acetate 30mg)
What is the most effective form of emergency contraception?
Most effective form of emergency contraception is IUD and can prevent pregnancy when fitted up to 5 days (120 hours) after unprotected sex or up to 5 days since the earliest time of ovulation.
Important features about the copper coil IUD
It can be left in place for ongoing contraception for up to 10 years.
It requires a trained medical professional to fit it, which involves a procedure similar to a smear where the coil is inserted through the cervical os.
The pharmacist generally would not be able to fit this. This is associated with a small risk of infection and perforation.
If used for ongoing contraception, it can affect periods, generally making them heavier and/or more painful.
MoA of EllaOne
This is a newer oral emergency contraceptive pill than levonorgestrel.
It binds with high affinity to progesterone receptors, and delays ovulation.
It has a license to be used up to 120 hours after unprotected sex.
Due to this binding to progesterone receptors, consideration needs to be made if an oral contraceptive is going to be used following this morning after pill.
Effectiveness of contraceptive injection
With perfect use, over 99% effective; fewer than 1 in 100 injection users will get pregnant in a year. With typical use, around 94% effective; around 6 in 100 injection users will get pregnant in a year.
MoA of contraceptive injection
Releases the hormone progestogen which stops ovulation, thickens cervical mucus to prevent sperm reaching an egg, and thins the lining of the uterus (womb) to prevent a fertilised egg implanting.
Advantages and disadvantages of contraceptive injection
Advantages- Lasts for 13 weeks (DepoProvera and Sayana Press) or 8 weeks (Noristerat).
You don’t have to think about contraception for as long as the injection lasts. May reduce heavy, painful periods for some people.
Disadvantages- Periods may stop, be in regular or last longer.
Periods and fertility may take time to return after stopping the injection.
Some people gain weight.
Important features of contraceptive injection
The injection can’t be removed from the body so any side effects may continue for as long as it works and for some time afterwards. Not affected by other medicines, diarrhoea or vomiting.
Effectiveness of contraceptive implant
100 percent effective once fitted. Fewer than one in 100 implant users will get pregnant in a year.
MoA of contraceptive implant
Small flexible rod put under the skin of the upper arm . Releases the hormone progestogen Come on which stops ovulation, thickens some cervical mucus to prevent sperm reaching an egg, and thins the lining of the uterus [womb] to prevent a fertilised egg implanting.
Advantages and disadvantages of contraceptive implant
Advantages- works for three years but can be taken out. You don’t have to think about contraception for as long as the implant is in place. When the implant is removed your periods and fertility were returned to normal.
Disadvantages-periods may stop or be irregular or last longer. It requires a small procedure to fit and remove it.
Important features of contraceptive implant
Put in using a local anaesthetic and no stitches are needed. Tenderness, bruising and some swelling may occur. You should be able to fill the implant with your fingers, but it can’t be seen. Some medicines may stop the implant from working.
Effectiveness of intrauterine system (IUS)
Over 99% effective once fitted. Fewer than one in 100 IUS users will get pregnant in the year.
MoA of IUS
A small T shaped plastic device, which slowly releases the hormone progestogen is put into the uterus [womb]. It thins the lining of the uterus to prevent a fertilised egg implanting and thickens the cervical mucus which makes it difficult for sperm to meet an egg.
Advantages and disadvantages of IUS
Advantages- works for three to five years depending on type, but can be taken out sooner. You don’t have to think about contraception for as long as the IUS is in place. With the Mirena IUS, periods usually become lighter, shorter and sometimes less painful. When the IUS is removed your fertility will return to normal.
• Disadvantages- irregular bleeding or spotting is common in the first six months . Very small chance of getting an infection during the first 20 days after insertion. Some people get ovarian cyst. Insertion can be uncomfortable.
Important features of IUS
You are taught to check the IUS is in place. Periods may stop altogether. A check for any existing infection may be advised before an IUS is put in. Not affected by other medicines. If fitted after 45, the Mirena IUS can stay in place until menopause.
Effectiveness of intrauterine device (IUD)
Over 99% effective once fitted. Fewer than one in 100 IUS users will get pregnant in the year.
MoA of IUD
A small plastic and copper device is put into the uterus. It stops sperm reaching an egg and may also stop a fertilised egg implanting in the uterus.
Advantages and disadvantages of IUD?
- Advantages- Works as soon as it’s put in. Works for 5-10 years depending on type but can be taken out sooner. You don’t have to think about contraception for as long as the IUD is in place. When the IUD is removed your fertility will return to normal.
- Disadvantages- May not be suitable if you’re at risk of getting a sexually transmitted infection. Periods may be heavier or longer and more painful. Very small chance of getting an infection during the first 20 days after insertion. Insertion can be uncomfortable.
Important features of IUD
You are taught to check the IUD is in place. Periods may stop altogether. A check for any existing infection may be advised before an IUD is put in. Not affected by other medicines. If fitted after 40, it can stay in place until menopause.
Effectiveness of tubal occlusion
The overall failure rate is about one in 200. Hysteroscopic sterilisation has a failure rate of around one in 500 over 5 years. This is a permanent method, suitable for people who are sure they never want children or don’t want more children.
MoA of tubal occlusion
The fallopian tubes are cut, sealed or blocked either by an operation or with a procedure called hysteroscopic sterilisation. This stops the egg and sperm meeting.