Contraception Flashcards

1
Q

Average conception rate per mid cycle intercourse

A

30%

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2
Q

Vasectomy failure rate

A

1:2000

Should not have unprotected intercourse until 3 months post procedure and a negative semen analysis

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3
Q

In women undergoing treatment for breast cancer, POPs do what to the rate of disease recurrence?

A

Increase

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4
Q

When can PCC be inserted up to in terms of day of cycle?

A

Day 19 of a 28 day cycle

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5
Q

When to insert copper IUD for emergency contraception

A

99% effective if inserted up to 120 hours after unprotected sex

**this is the gold standard method

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6
Q

Oral ECP type dose and timing

A

Levonorgestrel 1.5mg
72 hours (85% effective)
2-3% pregnancy rate after use

OR

Ulipristal acetate 30mg 120 hours (85% effective) 1-2% pregnancy rate after use

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7
Q

Natural family planning methods

A
The calendar method
Basal body temperature method
Billings method (ovulatory mucus)
Cervical palpatine method
Lactation also amenorrhea
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8
Q

Rhythm method

A

Length of menstrual cycle

Ovulation calculated as 14 day prior to onset of expected menstruation

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9
Q

Advantages of natural family planning

A

May be only option for those with religious or cultural belief
Not medical, no need to come to clinic
Makes women aware of ovulation cycle and natural fertility
Can enhance commuication and cooperation within a relationship

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10
Q

Disadvantages of natural family planning

A

Removes spontaneity of intercourse
Variation in length of follicular phase of the menstrual cycle which can indtroduce inaccuracies in ovulation prediction
Reliability of fertility awareness methods is likely to be reduced during BF, when discontinuing hormonal methods or during peri menopause

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11
Q

Types of combined hormonal contraception

A

Pills- Monophasic and bi/tri-physic
Transdermal patch
Vaginal ring

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12
Q

Combined contraception mode of action

A

Inhibit ovulation
Alters cervical mucus to reduce sperm penetration
Alters the endometrium, making it atrophic and unreceptive to implantation

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13
Q

Effectiveness of combined hormonal contraception

A

0.2 - 8:100 pregnancies depending on reliability of use

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14
Q

Advantages of combined hormonal contraception

A

Effective with correct use
Reliable
Reversible
Independent of intercourse
Can be used to treat menstraul problems
Can improve acne
Can be useful in managing symptoms of PCOS
Decreased risk of benign conditions in current users
Long term reduction in risk of carcinoma of the endometrium, ovary and bowel
Allows manipulation of the time of menstruation
Can assist with management of perimenopausal symptoms

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15
Q

Disadvantages of CHC

A

User-dependent (can reduce efficacy)
Minor hormonal SE (nausea, fluid retention, weight gain, breast tenderness)
Increased risk of VTE
Increased risk of arterial disease in the presence of other risk factors
Interactions with some drugs causes reduction of efficacy
Concomitant illness can affect absorption and reduce efficacy

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16
Q

Contraindications to COCP use (absolute)

A
Absolute:
Past or present CVD
Hx of VTE or anticoagulants
Thrombogenic mutations
Familial hypercholesterolaemia 
insulin-dependent DM with complications
BP >160/95
Smokers>35 years
BMI>40
Focal migraine with aura
Stroke
Major surgery with prolonged immobilization
Active liver disease
Porphyria
Medical condition affected by sex steroids
Undiagnosed genital tract bleeding
Estrogen dependent tumors (breast ca)
17
Q

Relative contraindications to COCP use

A

Fam hx of VTE <45
BP 140-159/90-94
BMI 30-35
Focal migraine with aura >5 years ago
Conditions requiring drugs that may interact
Medically treated and current gall bladder disease

18
Q

First generation progestogens

A

Norethisterone, noresthisterone acetate

19
Q

Second generation

A

Levonorgestrel

20
Q

Third generation

A

Desogestrel
Gestodene
Norgestimate

21
Q

Fourth generation

A

Drospirenone
Dienogest
Nomegestrol acetate

22
Q

VTE risk with generation of progestogens

A

2nd generation - 5-7 per 10000

3rd generation 9-12 per 10000

23
Q

Risk of VTE with CHC compared to non-users

A

Risk is double, but absolute risk remains very low