Contraception Flashcards
What are the methods which require the individual to do something vs methods which require a doctor to put something in someone?
Individual -
- Oral contraception (e.g. take pills 3 out of 4 weeks)
- Barrier (e.g. condoms)
- Fertility Awareness
- Coitus interruptus (pull out game strong)
- Oral emergency contraception
Doctor
- IUCD/IUI/IUS (e.g. coil)
- Progestogen Implants under skin / injections (e.g. depo provera injection in the buttock every 12 weeks)
- Sterilisation (e.g. closing UT/ tying up vas deferens
What are the risks of using contraception vs the risks of not using it?
Risks of using contraception
- Failure
- Infection
- Allergy
- CVS, neoplastic (can cause cancer)
- Can effect emotions/ psyche
- Iatrogenic - harm caused by doctors
Risk of not using contraception
- Higher chance of pregnancy
- Population growth
- Social and economic costs
What are the benefits of contraception vs effects of no contraception?
Benefits
- No pregnancy
- Psychosexual wellbeing - can have sex whenever you want
- Choice of when to conceive and prevent
- Sexual Health – condoms stop STDs
- Cost savings
- Female equality
- Pills help periods become lighter
Effects of no treatment
- No interference in a natural process
- No population growth
- Control of women
- Leads to quick consecutive pregnancies for women which are harmful (in developing countries)
Which 2 hormones des the combined oral contraceptive pill have?
Examples of pills?
Why are there so many types of pills?
Oestrogen (synthetic forms) and progestogens (compounds similar to progesterone)
Desogestrel, drospirenone
Different amounts of oestrogen and progesterone in them
How do oestrogens and progesterones act?
What would happen if you only gave oestrogen and not progesterone?
- On anterior pituitary & hypothalamus, so less GnRH, so less LH and FSH secreted due to –ve feedback, so follicle does not develop so you do not ovulate and no pregnancy
- Directly on the ovary
Endometrium would keep growing and comes out in a very heavy bleed
Where do progestogens act and to cause what?
- Anterior pituitary & hypothalamus
- Ovary
- Endometrium - thins it so it does not proliferate/ secrete so no implantation even if there is ovulation
- Uterine tubes - puts them to sleep so the cilia become lazy so gamete transport is delayed
- Cervical mucus - thinned so sperm is not allowed in in the first place
So what are the sites of action of COCP?
7
What are the benefits and risks of the COCP?
Benefits
- Highly reliable
- Safe
- Unrelated to coitus (intercourse)
- Woman in control
- Rapidly reversible – when you stop taking it, your cycle kicks starts again in a few days
- Halves risk of ovarian cancer + uterine cancer if taken long term
- No periods
- Helps endometriosis (cells of endometrium in other parts of internal female genital tract), menorrhagia (heavy periods), dysmenorrhoea (stomach cramps)
Risks
- CVS - high BP, increased risk of DVT (increase in clotting factors due to increase in oestrogen), vasospasms in brain vessels leading to stroke
- Neoplastic - increased risk of liver cancer
- GI - more insulin resistance due to oestrogen leading to diabetes, weight gain, Crohn’s disease
- Hepatic - congenital non haemolytic anaemia, jaundice (yellowing of the skin and the whites of the eyes due to build up of bilirubin), gall stones
- Dermatological - chloasma (skin discolouration due to too much oestrogen), acne, erythema multiforme (skin reaction)
- Psychological - mood swings, depression, lower libido
How is the COCP taken and why is it dangerous to miss the pill in your last few days/ forget to take the next packs pills for a few days?
Take 21 pills, one each day, and stop for 7 day break (pill free interval in which you have some bleeding due to withdrawal from hormones)
Since you stop for 7 days but the HPG axis suppression lifts after 10 days, carelessness with pill taking can cause the suppression to lift and ovulation to occur
Why must you ask a woman patient if they are taking any contraceptives?
Medications can interact with the contraceptives e.g. Liver enzyme inducing drugs affect metabolism of oestrogen and progestogen, rifampicin and anti-epileptics, broad spectrum antibiotics
which affect enterohepatic circulation of oestrogen only (40% of pill is recycled every time it goes through your gut)
What is the ring? What are it’s advantages and disadvantages?
COCP but instead of a pill, it is in ring form
Advantage - don’t have to take it everyday, just place in vagina for 21 days
Disadvantage - Have to remember to take it out after 21 days
What are examples of progestogen only methods of contraception?
What is the benefit of a device implanted in arm?
- Implants e.g. Nexplanon; implanted subcutaneously; long acting and reversible
- Hormone releasing IUCDs e.g. Mirena IUS; releases progesterone into uterus
- Progesterone Only Pills (POPs) e.g. desogestreal (cerelle)
- Injectables e.g. Depo Provera; 12 weekly intramuscular injection in the buttock; high conc. progesterone
The hormones are not reliant on being absorbed into your body, they are instead immediately absorbed into the arms circulation
Why is Cerella better than older POPs?
- No oestrogen – if given to women who are breastfeeding and you give oestrogen their milk dries up
- Better side effect profile
- Bleeding is regular/ as predictable as COCPs
- 12 hour window to take the pill in case you missed it
What shape are copper bearing IUDs?
What benefits do they have?
Small and C shaped
- Destroys spermatozoa (copper is spermicidal)
- Prevent implantation – inflammatory reaction due to foreign body present in the uterus; known as endometritis; even if sperm gets through there is no implantation
- Prostaglandin secretion
- Mechanical effect
What are the 2 types of IUDs?
How long do they last for?
What happens if given to women around age 40?
What is a drawback of them?
Copper bearing and hormone bearing e.g. Mirena
Minimum of 5 years
Can lead them to menopause due to their fertility declining
Time limited as progesterone runs out so must be replaced