Contraception Flashcards
How long a supply can oral contraceptives be prescribed for and why?
Up to 12 months in order to avoid unwanted discontinuation and increased risk of pregnancy.
What must be done before supplying another 12 months of oral contraception?
Review of medical eligibility, satisfaction, adherence, drug interactions, and consideration of alternative contraception.
BP and BMI must also be recorded annually.
Who is the combined oral contraceptive not suitable for?
> 50
Diabetes with comorbidity
Migraine with aura
CVD or multiple risk factors
Obese (BMI>35kg/m^2)
Hypertension
VTE - curent or history, not recommend if family history or immobile.
Smoking - not recommended
Menopause - not recommended
Lamotrigine - reduces lamotrigine
Who is the IUD not recommended for?
Abnormal vaginal bleeding
Pelvic inflammatory disease
STI
When should someone with vomiting/diarrhoea follow the missed pill rule?
If vomiting occurs within 3 hours of taking or severe diarrhoea occurs within 24 hours.
How does COC work?
Oestrogen and progesterone inhibit ovulatoin by acting on the hypothalamo-pituitary axis to reduce leutinising hormone (LH) and follicile-stimulating hormone (FSH) production.
What are the types of COC pill?
Monophasic - fixed amount of oestrogen and progesterone in each pill. 21-day dosing schedule.
Multiphasic - varying amounts of the 2 hormones in each table. 28-day dosing schedule. Can be biphasic, triphasic, or quadraphasic.
What are the active ingredients in COC?
Oestrogen in the form of ethinylestradiol
Progesterone in the form of levonorgestrel or norethisterone.
What are the different possible regimens for the monphasic COC?
Traditional - 21 days continuous use, 7-day hormone-free interval (HFI).
Shortened HFI - 21 days continuous use, 4-day HFI.
Tricycyling - 9 weeks continuous use followed by 4 or 7 day HFI.
Flexible extended use - continuous use followed by 4-day HFI when breakthrough bleeding occurs.
Continuous - continuous use with no HFI.
Is it better to use the traditional regimen over tailored regimens of COC?
There is no difference in efficacy or safety of using the traditional regimen which mimics the natural menstrual cycle over a tailored regimen.
In fact, traditional regimen may be associated with disadvantages such as heavy/painful withdrawal bleeds, headaches. mood changes, and increased risk of incorrect use with sibsequent unplanned pregnancy.
What are some adverse effects associated with COC?
Nausea
Bloating
Irritability
Increased risk of breast cancer
What are some benefits of COC?
Reduced risk of ovarian, endometrial, and colorectal cancer.
Reduced dysmenorrhoea and menorrhagia.
Management of PCOS, endometriosis, and PMS.
Improvement of acne
Reduced menopausal symptoms.
Maintaining bone density in peri-menopausal female under 50 years.
When should women start using the COC?
At any time, unless:
Postpartum breastfeeding - 6 weeks, 7 day barrier method.
Postpartum not breastfeeding - day 21, 7 day barrier method.
Miscarriage/abortion - gestation <24 weeks, within 5 days, no barrier. Gestation >24 weeks, 6 weeks, 7 day barrier method.
When do women require barrier method when starting COC?
Depends on the stage of their cycle:
Day 1 (day 1 of period) - no barrier.
Day 2-5 - no barrier unless taking Qlaira (9 days barrier) or Zoely (7 days barrier).
Any other time - 7 days barrier, 9 for Qlaira.