Contraception Flashcards

1
Q

What phase of the menstrual cycle does menstruation occur?

A

Follicular phase

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2
Q

What phase of the menstrual cycle does ovulation occur?

A

Luteal phase

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3
Q

During the menstrual cycle what stimulates the LH and FSH surge (ovulation)?

A

The surge in estrogen during proliferation

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4
Q

What hormone builds up the endothelium lining during the luteal phase?

A

Progesterone

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5
Q

Which contraception is the MOST effective?

A

Implant (nexplanon)
IUD

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6
Q

Dospirenone

A

Progesterone component of COC has mild potassium sparing diuretic effects to decrease bloating and weight gain

Help with other symptomd because of the anti-androgenic effects (less acne)

SE: increased POTASSIUM
higher risk of clots
do NOT use with kidney,liver, or adrenal gland disease

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7
Q

What is the purpose of using COC in PCOS?

A

To help regulate menses
1st line treatment in PCOS!

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8
Q

What is the treatment for endometriosis?

A

COC

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9
Q

What is the most ideal population to take progestin only pills if they don’t have clot risk?

A

Breast feeding patients
***estrogen will decrease milk production :(

Sometimes used for migraine prophylaxis (safe with migraines with aura!)

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10
Q

What contraception formulation has a higher systemic estrogen exposure?

A

Patch (Xulane)
- less effective if > 198 lbs

**do NOT use in patients > 35 years old who smoke!!!!!

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11
Q

A patient wants to take continued COC and not have a period anymore. What COC is approved for this?

A

Amethyst

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12
Q

What is COC extended cycle?

A

84 days of active hormonal pills (3 months) followed by 7 days of very low dose estrogen ===== bleeding will occur every 3 months

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13
Q

What are some examples of progestin only pills?

A

Errin
Camila
Nora-BE

“norethindrone”

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14
Q

A female patient wants to try a extended cycle COC. What would you recommend?

A

Seasonique

EE + LNG

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15
Q

What are the ADRs of estrogen?

A

Nausea
Breast tenderness
Bloating
Weight gain
increase BP
Melasma (dark patches on skin)

Serious: thrombosis!!!!!

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16
Q

What is the signs of DVT/PE?

A

ACHES
Abdominal pain
Chest pain
Headache
Eye problems
Swelling

17
Q

What are the ADR of progestin?

A

breast tenderness
headache
fatigue

18
Q

A patient on Loestrin comes to your women’s health clinic complaining of breakthrough bleeding. What is your recommendation?

A

Increase daily estrogen dose, increase to a non “Lo” contraception

19
Q

A patient on Sprintec comes complaining of breakthrough bleeding. What would your recommedation be?

A

Since the patient is already receiving > 35 mcg per day of estrogen… try switching the progestin product

Sprintec (norgestimate) - switch to Junel (norethindrone)
Yaz (Drospirenone)
Seasonique (Levonorgestone)

20
Q

When should you NOT use combined contraceptives?

A

-Women > 35 years who smoke
-history of DVT/PE, CAD, thrombosis or hypercoagulopathies
- history of breast, ovarian, or liver cancer
-women with migraines with aura

21
Q

A patient comes into your pharmacy on Yasmin complaining of nausea. What would your recommendation be?

A

DECREASE estrogen component of birth control
- switch to “lo” COC

22
Q

What medications must you watch out for that may decrease the efficacy of hormonal birth control?

A

Antibiotics (rifampin)
Anticonvulsants (carbamazepine, topiramate, lamotrigine, primidone)
St. John’s wor
Smoking!!!!!!
Ritonavir
Colesevelam (Welchol)
Byetta

23
Q

A patient was just diagnosised with hep C and was put on Mavyret. Other medications include: Junel and Altace. What major problem do we have with this new medication?

A

Junel is COC with estrogen. Estrogen in combo with Mavyret ===== LIVER TOXICITY

24
Q

When do POP start having full pregnancy protection as you start?

A

48 hours after

25
Q

A patient comes to you and says she missed a dose of Aviane 36 hours ago and asks if she needs to use back-up. She has not missed any other pills in the past week.

A

NO, it has been < 48 hours since her missed dose

26
Q

A patient comes to you and says she missed a dose of Camila 36 hours ago and asks if she needs to use back-up. She has not missed any other pills in the past week.

A

YES this is POP
You need back up contraception for 48 hours!!!!
***consider EC if unprotected sex within the last 5 days

27
Q

What are the emergency contraception options?

A

Copper IUD - good within 5 days
Ella (upristal) - good within 5 days
Plan B (levonogestrel) - good within 3 days

28
Q

Depo Provera

A

Medroxyprogesteone IM injection every 3 months

  • can cause DECREASE bone density
29
Q

Infertility caused by anovulation can be treated with?

A

Clomiphene (SERM)
or
Letrozole (aromatase inhibitor)
or
Gonadotropins