Content Flashcards
Physiologic jaundice
Presents between days 3-5 and is due to normal breakdown of fetal hemoglobin and immature liver metabolism, causing increased unconjugated bili
Pathologic jaundice
Increased conjugated bili; or occurs in the first 24 hours of life
How much of the med does baby receive through breast milk
1%
How long does pumping and dumping have to occur for
3-5 1/2 lives of the drug
6 month red flag
no smiles
9 month red flag
No sharing of sounds or other facial expressions
12 months red flag
Lack of response to name, no babbling, no pointing or reaching or waving
16 months red flag
No spoken words
24 months red flag
No 2 word phrases
Screening for type 2 DM in children
Begins at age 10 if at risk and continues every 2 years
Pharmacology agents for dyslipidemia in peds
If >8 years and LDL >190 + >2 risk factors
Limit cows milk after 12 months to
16-24oz per day
BP monitoring in peds
> 3 years old
MMR and infant travelling abroad
1 dose can be given between 6 and 11 months
MMR vaccine in lactation/pregnancy
safe in lactation, CI in pregancy
When was universal Hepatitis B vaccine recommended
For infants in 1991, for adolescents in 1996
Complications of varicella
Bacterial skin infections, pneumonia, encephalitis, toxic shock, reyes syndrome
If a child >12 months has been exposed to varicella
Give vaccine within 3-5 days to prevent disease
Tx pertussis
Azithromycin
Do not give IPV if allergic to
Neomycin, streptomycin or polymyxin B
Plumbism
Lead poisoning
Lead poisoning leads to
Iron deficiency anemia has it inactivates heme synthesis
What enhances lead absorption
Diet low in Ca, Iron, Zn, Mg, Cu and high in fat
Sx of lead poisoning
Abdominal pain, constipation, difficulty sleeping, HA, irritable, low appetite, loss of skills
Bronchiolitis
Due to RSV
Wheezing, tachypnea, fever, conjunctivitis, pharyngitis
2-3 week course
Supportive therapy
Palivizumab can be used as prophylaxis for preemies or infants with congenital heart disease
Tx of hemangioma
Oral propanolol, systemic steroids, interferon alpha
Erythema toxicum neonatorum
Benign rash resembling flea bites; usually resolves in 5-7 days
AOM most common bacterial pathogens
Strep pneumoniae, H. Influenzae, Moraxella catarrhalis
Most common predisposing factor to AOM
Eustachian tube dysfunction due to URI
1st line tx AOM
High dose amoxicillin
Targeted at strep pneumoniae due to low rate of spontaneous resolution
if penicillin allergy: cefdinir, cefuroxime, ceftriaxone
If abx failure after 48-72 hours, try Augmentin or ceftriaxone
Tympanostomy tubes recommended for
Chronic >3 monts bilateral OME
Risk factors for bacterial sinusitis
Viral infection, allergies, second hand smoke, sinus abnormalities
Consider ABRS if
New fever at day 6/7 or persistence of cold >10 days
Most common causes of ABRS
Strep pneumoniae or H influenzae
Tx sinusitis
amoxicillin
UTI manifests in younger children as
irritability, lethargy, fever
Biggest cause of UTI in children
Vesicoureteral reflex
Tx of UTI in children
Amoxicillin, Bactrim or 2nd/3rd cephalosporin for 7-10 days
Cipro approved for >1 year old
Rubella
Fever, sore throat, malaise, nasal discharge, maculopapular rash, posterior lymph nodes 5-10 days before rash
Marker of effective asthma control
Nocturnal sx
Theophylline approved for
> 5 years old
Levalbuterol vs albuterol
Levalbuterol has greater bronchodilation and fewer SE at lower dose than albuterol
Most common cause of gastroenteritis in kids
Norovirus
Shigellosis
Fever, bloody stools
tx: bactrim
When do girls typically achieve adult height
1 year after menstruation
Adrenarche
Development of pubic hair
Tanner 2
Males: testes enlarge, scrotal reddening, long and sparse pubic hair at base of penis
Females: Breast buds and papilla elevated, downy hair along labia majora
Tanner 3
Males: Penile length increased, scrotal enlargement, dark pubic hair and coarser, growth spurt
Females: breast mound, coarser and curling pubic hair, growth spurt
Tanner 4
Males: increased penile length and width and development of glans; adult pubic hair but no spread
Females: areola and papilla elevated to form second mound, adult pubic hair with no spread, menarche
Tanner 5
male: hair spreads to thighs
Female: hair spreads to thighs
What should not be used if pt has varicella
Ibuprofen
Risk of NEC
Early indicator of hypoperfusion in kids
Cap refill <2 seconds
Initial tx of bacterial meningitis in children
Ceftriaxone with vancomycin
Most sensitive finding for pneumonia in children
Tachypnea
Tx pneumonia in children
Amoxicillin to cover strep pneumoniae
Macrolide to cover atypicals
Dx criteria for kawasaki disease
Fever >5 days
Erythema, edema and peeling of extremities
Bilateral nonexudative conjunctivitis
polymorphous rash and cervical lymphadenopathy
Strawberry tongue
-Obtain echo early as it can cause coronary artery obstruction
Tx: immunoglobulin IV and aspirin
Bells palsy
Acute paralysis of CN 7 due to inflammation
- Can be linked to virus
- Obtain antibody testing to lyme disease
- Tx: steroid
Tx cluster HA
Triptans, high dose NSAIDs, high flow O2
Triptans
Serotonin receptor agonists
-Cause vasoconstriction: CI in CAD or pregnancy
Ergotamines
Act as 5-HT1A and 5-HT1B agonists; do not affect cerevrak blood flow
- Cause vasoconstriction: CI in CAD or pregnancy
- Not helpful for tension HA
HA provoking meds
estrogen, progesterone, vasodilators
Beta blockers used for HA prophylaxis
Metoprolol, propranolol, atenolol
Incubation period for bacterial meningitis
3-4 days
CSF findings in bacterial meningitis
Pleocytosis, increased CSF opening pressure, 90-95% neutrophils, decreased glucose, increased protein
Which type of meningitis causes rash
N. Meningitidis
Chemoprophylaxis bacterial meningitis
Single dose Cipro or IM ceftriaxone or 4 doses rifampin
Sx of MS
Weakness/numbness of limb Monoocular visual loss Diplopia Vertigo Facial weakness Ataxia Nystagmus Heat sensitivity -Most common b/w 20 and 40 years Tx exacerbations: steroids Long term Tx: interferon beta 1-b
Dopamine agonists
Tx PD
Ropinirole and prampexole
-Better SE than levodopa
TIA
Stroke like sx resolve within 24 hours
Agents to decrease BP post stroke
Thiazide diuretic, CCB, ACEI/ARB
Temporal arteritis
Autoimmune vasculitis most common 50-85 years
- Causes inflammation
- Tender, pulseless vessels and severe unilateral HA’
- Most serious complication: blindness
- Tx: high dose steroids (prednisone) then low dose 6 months-2 years; give with PPI and biphosphanate + Ca.Vit D
- Dx: arterial biopsy
Types of skin lesions
Macule: Flat <1cm (freckle)
Patch: Flat >1cm (vitiligo)
Papule: Raised <1cm (raised nevus)
Vesicle: Fluid filled <1cm (herpes)
Plaque: Raised >1cm (psoriasis)
Purpura: petrchiae, ecchymosis
Pustule: Vesicle like with purulent content (acne, impetigo)
Wheal: circumscribed area of skin edema (hive)
Nodule: raised >1cm, mobile (epidermal cyst)
Bulla: fluid filled >1cm (burn blister)
Lease potent topical steroid
Hydrocortisone
Absorption rates of lotion, cream, ointment
Lotion < cream < ointment
Impetigo
2-5 years peak
Due to GAS or staph aureus
Tx with mupirocin if small lesions
-Bacitracin and neomycin not recommended
Acne inducing drugs
lithium, dilantin
Tx post herpetic neuralgia
TCAs, gabapentin, pregabalin, topical lidocaine
Onychomycosis
Nails are dull, thickened
-Nail fungal infection
Basal cell carcinoma
PUT ON Pearly papule Ulcerating Telangiectasis On face, scalp, pinnae Nodules are slow growing
Squamous cell carcinoma
-evolves more rapidly NO SUN Nodular Opaque Sun exposed areas Ulcerating Nondistinct borders
Actinic keratoses can evolve into
Squamous cell carcinoma
Sandpaper quality
Tx: liquid nitrogen cyrotherapy
Tx cellulitis if no MRSA risk
Dicloxacillin or azithromycin