constituents of the blood: Red and white blood cells Flashcards
1
Q
life span of red blood cell
A
100-120 days
2
Q
size of red blood cells
A
6.2-8.2x2-2.5 um
3
Q
problems with RBC
A
• Anaemia-hypoxia (too low)
Hypo-regenerative vs. hyper-regenerative
Reduced production vs. increased destruction
Corpuscular vs. extra-corpuscular
• Polycythaemia (PRV)- thrombosis (too high)
Primary vs. secondary
Hand foot syndrome- dactylitis, one of the first complications of sickle cell syndromes, painful swelling of hands and feet
4
Q
size of white blood cells
A
7-30um
5
Q
life span of white blood cells
A
hours/days/years
6
Q
address of red blood cells
A
bone marrow-blood
7
Q
address of white blood cells
A
thymus/bone marrow-blood/lymphatic organs
8
Q
WBC abnormalities
A
- Neutrophil leukocytosis/neutropenia
- Eosinophilia/eosinopenia
- Basophilia
- Monocytosis/monocytopenia
- Lymphocytosis/ lymphopenia
- Myeloid malignancies (AML,MDS,MPN)
- Lymphoid/plasma cell malignancies (ALL lymphoma-T/B/NK, HG-LG, Hodgkin/Non-Hodgkin, multiple myeloma