constituents of the blood: Red and white blood cells Flashcards

1
Q

life span of red blood cell

A

100-120 days

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2
Q

size of red blood cells

A

6.2-8.2x2-2.5 um

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3
Q

problems with RBC

A

• Anaemia-hypoxia (too low)
Hypo-regenerative vs. hyper-regenerative
Reduced production vs. increased destruction
Corpuscular vs. extra-corpuscular
• Polycythaemia (PRV)- thrombosis (too high)
Primary vs. secondary
Hand foot syndrome- dactylitis, one of the first complications of sickle cell syndromes, painful swelling of hands and feet

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4
Q

size of white blood cells

A

7-30um

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5
Q

life span of white blood cells

A

hours/days/years

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6
Q

address of red blood cells

A

bone marrow-blood

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7
Q

address of white blood cells

A

thymus/bone marrow-blood/lymphatic organs

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8
Q

WBC abnormalities

A
  • Neutrophil leukocytosis/neutropenia
  • Eosinophilia/eosinopenia
  • Basophilia
  • Monocytosis/monocytopenia
  • Lymphocytosis/ lymphopenia
  • Myeloid malignancies (AML,MDS,MPN)
  • Lymphoid/plasma cell malignancies (ALL lymphoma-T/B/NK, HG-LG, Hodgkin/Non-Hodgkin, multiple myeloma
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