constituents of the blood: Red and white blood cells

Question 1

life span of red blood cell

Answer 1

100-120 days

Question 2

size of red blood cells

Answer 2

6.2-8.2x2-2.5 um

Question 3

problems with RBC

Answer 3

• Anaemia-hypoxia (too low)
Hypo-regenerative vs. hyper-regenerative
Reduced production vs. increased destruction
Corpuscular vs. extra-corpuscular
• Polycythaemia (PRV)- thrombosis (too high)
Primary vs. secondary
Hand foot syndrome- dactylitis, one of the first complications of sickle cell syndromes, painful swelling of hands and feet

Question 4

size of white blood cells

Answer 4

7-30um

Question 5

life span of white blood cells

Answer 5

hours/days/years

Question 6

address of red blood cells

Answer 6

bone marrow-blood

Question 7

address of white blood cells

Answer 7

thymus/bone marrow-blood/lymphatic organs

Question 8

WBC abnormalities

Answer 8

• Neutrophil leukocytosis/neutropenia
• Eosinophilia/eosinopenia
• Basophilia
• Monocytosis/monocytopenia
• Lymphocytosis/ lymphopenia
• Myeloid malignancies (AML,MDS,MPN)
• Lymphoid/plasma cell malignancies (ALL lymphoma-T/B/NK, HG-LG, Hodgkin/Non-Hodgkin, multiple myeloma