Constipation

Question 1

What type of laxativie is laxido

Answer 1

Osmotic

Question 2

Picolax is a bowel cleansing prep - what type of laxative is it?

Answer 2

Stimulant

Question 3

Examples of bulk forming laxatives

Answer 3

ispaghula husk, bran, methylcellulose, sterculia

Question 4

how long does it take for bulk forming laxatives to work?

Answer 4

72 hour s

Question 5

symptoms associated with bulk forming laxatives

Answer 5

flatulence, bloating, cramping - need adequate fluid intake to avoid obstruction

Question 6

Stimulant laxative examples

Answer 6

Senna, Bisacodyl, sodium picosulfate, co-danthramer

Question 7

What condition should stimulant laxatives be avoided in?

Answer 7

Intestinal obstruction

Question 8

What patients is co-danthramer and co-danthrusate limited to?

Answer 8

Palliative - potential of carcinogenicity

Question 9

Which laxatives work by decreasing the surface tension and increasing penetration of intestinal fluids into faecal mass?

Answer 9

Faecal softners

Question 10

What does lactulose do to the faecal pH?

Answer 10

Lowers it

Question 11

Linaclotide is licensed to treat moderate-severe constipation in what disease condition?

Answer 11

IBS

Question 12

Prucalopride is a 5HT4 agonist - what special property does it have?

Answer 12

Prokinetic

Question 13

What laxative should be used first in treatment of contipation

Answer 13

Bulk + diet

Question 14

What laxatives should be used and which are to be avoided in opioid induced constipation?

Answer 14

Use - osmotic

Avoid - bulk

Question 15

Naloxegol is a laxative used when?

Answer 15

Opioid induced constipation - when failure to respond to anything else

Question 16

First line treatment of contipation in children

Answer 16

• dietary modification + laxative or behavioural modification –> Diet alone is NOT recommended as first line

Question 17

Which laxative if preferred first line in children

Answer 17

Osmotic - laxido

Question 18

What is the maximum amount of Laxido/Movicol a patient with cardiovascular impairment should receive in 1 hour?

Answer 18

4 x half sachets or 2 full strength in any one hour

Question 19

What time of the day should MgOH be given?

Answer 19

Bedtime

Question 20

How long does it take for docusate to act?

Answer 20

orally - 1 to 2 days, rectally 20 mins

Question 21

Onset of action of senna

Answer 21

8 - 12 hours

Question 22

sennais on sale OTC to children over what age?

Answer 22

12