Constipation Flashcards
What type of laxativie is laxido
Osmotic
Picolax is a bowel cleansing prep - what type of laxative is it?
Stimulant
Examples of bulk forming laxatives
ispaghula husk, bran, methylcellulose, sterculia
how long does it take for bulk forming laxatives to work?
72 hour s
symptoms associated with bulk forming laxatives
flatulence, bloating, cramping - need adequate fluid intake to avoid obstruction
Stimulant laxative examples
Senna, Bisacodyl, sodium picosulfate, co-danthramer
What condition should stimulant laxatives be avoided in?
Intestinal obstruction
What patients is co-danthramer and co-danthrusate limited to?
Palliative - potential of carcinogenicity
Which laxatives work by decreasing the surface tension and increasing penetration of intestinal fluids into faecal mass?
Faecal softners
What does lactulose do to the faecal pH?
Lowers it
Linaclotide is licensed to treat moderate-severe constipation in what disease condition?
IBS
Prucalopride is a 5HT4 agonist - what special property does it have?
Prokinetic
What laxative should be used first in treatment of contipation
Bulk + diet
What laxatives should be used and which are to be avoided in opioid induced constipation?
Use - osmotic
Avoid - bulk
Naloxegol is a laxative used when?
Opioid induced constipation - when failure to respond to anything else
First line treatment of contipation in children
- dietary modification + laxative or behavioural modification –> Diet alone is NOT recommended as first line
Which laxative if preferred first line in children
Osmotic - laxido
What is the maximum amount of Laxido/Movicol a patient with cardiovascular impairment should receive in 1 hour?
4 x half sachets or 2 full strength in any one hour
What time of the day should MgOH be given?
Bedtime
How long does it take for docusate to act?
orally - 1 to 2 days, rectally 20 mins
Onset of action of senna
8 - 12 hours
sennais on sale OTC to children over what age?
12
