Constipation Flashcards

1
Q

Define constipation

A

Unsatisfactory defaecation due to infrequent stools, difficult stool passage or seeming incomplete defaecation.
Typically passing less than three stools a week
Most common in women, elderly and pregnancy.

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2
Q

What type of constipation should be further investigated?

A

New onset
Esp in 50yrs+ with anaemia, abdo pain, weight loss, overt/occult blood - due to risk of malignancy.
If accompanied with vomiting/absolute/ suspect BO.

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3
Q

What lifestyle advice can help treat constipation?

A

In dietary fibre - should be done gradually to avoid flatulence and bloating.
Foods high in fibre and sorbitol - such as prunes, peaches or fruit juices.
Increased fluid intake
Regular exercise
Toiler routine changes - ensures goes when feels the need, takes time to ensure defecation is complete

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4
Q

What electrolyte abnormality is common in laxative abuse?

A

Hypokalemia.

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5
Q

What are the different types of laxatives?

A

Bulk-forming - inc stool weight and soften it (fibrogel)
Stimulant - stimulate nerves in colon
Faecal softeners - inc water and fat in stool
Osmotic laxatives - draw water into colon

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6
Q

What are the different stool types on a Bristol Stool Chart?

A
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7
Q

Give an overview of bulk-forming laxatives

A

Examples – fybogel
Mechanism – indigestable hydrophilic colloids – absorb water and swell – increasing faecal mass and GI wall distention – stimulate peristalsis
Usually takes 2-3days to work, often used in IBS, Diverticulitis and safe in elderly
Side effects = bloating and flatulence, interfere with warfarin absorption,
Cautions = needs to be taken with fluids or can cause a blockage – avoid in fluid restricted patients. Use with care if risk of obstruction such as strictures or many adhesions

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8
Q

Give an overview of osmotic laxatives

A

Example – lactulose, milk of magneisum, glycerin, macrogol
Mechanism – poorly absorbable and hydrophilic -> keep water in the lumen, fecal matter not as hard, easier to pass. Can work in as fast as 1hr
Side effects – high risk of dehydration and electrolyte imbalances in patients with renal failure (cautious in elderly). Cramping and bloating.

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9
Q

Give an overview of stool softners

A

docusate
Mechanims – allows water and lipid to penetrate stools -> softer and easier to pass.
Usually take longer than other laxatives, used in patients who should not strain such as post surgical, post natal, hemorrhoids, HTN or hernias.

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10
Q

Give an overview of stimulant laxatives

A

example = senna
Cause direct stimulation of ENS and colonic secretions. Takes 8-24hrs to work
Side effects – accumulation of melanin causes urine and bowel discoloration.

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11
Q

What are some symptoms of constipation?

A

Fewer than three bowel movements a week
Difficult time passing stools
Lumpy or hard stools
A feeling of being blocker or of not having fully emptied your bowels.
Elderly may also present with constipation

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12
Q

What are some medical conditions that can cause constipation?

A

Neurological - stroke, Parkinsons disease, spinal cord injury
Diabetes
Tumours or blockages
Pelvic floor disorders, Irritable bowel syndrome.
Alzheimers disease - not causative but can increase the risk
Medications - Parksinsons disease drugs, iron supplements, anaesthesia, opiods

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13
Q

At what point is constipation considered chronic?

A

3 months or more

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14
Q

What is important to ask about the patients bowel motions if they are constipated?

A

How often? normal?
Consitency?
Colour?
Bloor or mucous?
Pain or straining?
Feeling incomplete emptying of stools?
Duration

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15
Q

What associated symptoms need to be considered in a patient with constipation?

A

Abdo pain
Abdo distention or bloating
Nausea or vomiting - faeculent or bilious
Loss of appetite
Overflow diarrhoea
Urinary retention
Any confusion or derlirium

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16
Q

What are the red flags for constipation?

A

Colorectal cancer - sudden change in bowel habit, bleeding, weight loss, fatigue, malaise, nigh sweats, iron deficiency anaemia
Ovarian cancer - change in bowel habit, bloating, early satiety, pelvic/abdopain, urinary urgency or frequency, women over 50yrs.
BO - constipation, vomiting, bloating

17
Q

What are the signs of constipation of abdominal examination?

A

Distention
Abdominal massess
Liver enlargement
Tendernesss
Increased/decreased bowel sounds

18
Q

What are the signs of constipation on perineal inspection?

A

Skin tags
Fissures
Prolapse
Anal warts
Perianal ulceration

19
Q

What are the signs of constipation on digital rectal examination?

A

Inner haemorrhoids
Sphinter tone
Tenderness
Obstruction/stenosis
Impacted faeces
Completed absence of stool
Tumour masses
Blood

20
Q

What are the physical risk factors for constipation?

A

Older age
Female sex
Immobility
Dehydration
Seating position when passing bowel motion
Medications - opioids, oral iron

21
Q

What are some social risk factors for constipation?

A

Low fibre diet
Low calorie intake
Low water intake
Limited exercise
Family history of constipation
Socio-economic deprivation
Ignoring the urge to go to the toilet

22
Q

What are some psychological risk factors for constipation?

A

Anxiety/depression
Eating disorders
Somatization disorders
History of sexual abuse.

23
Q

What is meant by secondary constipation?

A

Medical conditions that can cause constipation

24
Q

What are some GI tract conditions that can lead to secondary constipation?

A

IBD
Colorectal cancer
Rectal prolapse
Haemorrhoids
Anal fissures and strictures
Pelvic floor damage

25
Q

What are some endocrine and metabolic conditions that can cause constipation?

A

Diabetes - autonomic neuropathy
Hypothyroidism
Hypercalcaemia
Hyperparathyroidism
Hypokalaemia
Hypermagnesaemia

26
Q

What are some neurological conditions that can cause constipation?

A

cerebrovascular disease e.g stroke
MS
Parkinsons disease
Autonomc neuropathy
Hirchsprungs disease

27
Q

What type of laxatives should be given for opioid induced constipation?

A

Osmotic (laxido)
Stimulant (Senna)

28
Q

What laxatives tend to be used for acute and chronic constipation?

A

1st line - bulk forming (isphagula husk)
2nd - if hard stool and difficult to pass add/switch to osmotic e.g laxido
3rd - change to diff type of osmotic - lactulose

2nd if soft but difficult to pass - stimulant e.g senna
3rd prokinetic e.g prucalopride

29
Q

What laxatives should be used for faecal impaction?

A

Complication of chronic constipation (Faeces merges unable to pass)
1st for hard stools - osmotic e.g laxido
1st for soft stool - stimulant e.g senna
2nd - suppositories or mini enema
3rd - enema phosphate

30
Q

What surgical interventions may be used for constipation?

A

Manual evacuation
In severe cases, colectomy +/- stoma formation e.g subtotal colectomy with ileorectal anastamosis