Conquest Of Blood Transfusion

Question 1

What was the problem of blood transfusion

Answer 1

Immunological compatibility, coagulation, and Storage

Question 2

First Blood transfusion was done by?

Answer 2

Jean Baptiste Dennis, in 1667

Question 3

What did Jean Baptiste Dennis do?.

Answer 3

He transfused a 17yr old boy with 270mls of blood fron the carotid artery of a sheep

Came with no adverse reaction, surprisingly

Question 4

When was blood transfusion banned in France?

Answer 4

17th April 1668, this was because it proved abortive after Jean Baptiste trial.

Question 5

Who first did man to man transfusion?

Answer 5

James Blundell of Guy hospital, 1818

Question 6

What Did James Blundell do?

Answer 6

Had to tranfuse blood with syringe immediately after collecting the blood …

Reason is to avoid blood coagulation and clotting

Question 7

What happened in 1900

Answer 7

Karl Landsteiner discovered the three different blood groups in his laboratory in Vienna.

Explained the adverse reaction of blood, coagulation was due to agglutinin presence

Question 8

What did M Hustin of Belgium do?

Answer 8

He introduced blood preservation using sodium citrate as anticoagulant ,in YEAR 1914

Question 9

What happened in 1916

Answer 9

Rous and Turner prolonged the lifetime of RBC by adding Glucose

Question 10

Progression of Events.
1667—-➡️ Transfusion using 270mls of carotid blood of sheep

1668(17/04)–➡️ France and other countries were banned from blood transfusion

1818—➡️Man to man transfusion happened in guy’s hospital

1900– ➡️ Karl Landsteiner discovered the blood groups and effect of agglutinin.

1914➡️ Blood preservation using sodium citrate was introduced

1916➡️ Glucose was added to preserve RBC

1937➡️ Blood bank organisation in cook country hospital Chicago.

1943➡️ Blood preservation lasted for 21days due to addition of acid citrate and dextrose.

Answer 10

1667➡️ Jean Baptiste Dennis.
1818➡️James Blundell
1900➡️ Karl Landsteiner
1914➡️M.Hustin of Belgium
1916➡️Rous and Turner
1937➡️Benard Fantus
1943➡️Loulit and Mollison

Question 11

What happened in 1935?

Answer 11

Benard Fantus organized a blood bank in cook country hospital Chicago.

Question 12

What did Loulit and Mollison do in 1943

Answer 12

They added acid citrate and dextrose to blood mixture increasing it’s lifespan to 21days