Connective Tissue Flashcards
stroma
connective tissue that surrounds tissue component of organ
parenchyma
functioning part of organ
functions of connective tissue
- mechanical support and protection of soft tissue
- physiological support (molecular exchange)
a. forms a pathway for blood vessels and nerves
b. fluids of connective tissues act as a medium of exchange for metabolites between tissues and blood vessels - storage of energy in the form of fat
- defense against infection
- repair of injuries
- maintain boundaries
- cell adhesion and movement
components
fibres, ground substance, cells
ground substance
aqueous, tends to be removed
collagen properties
round and squiggly; inelastic; tensile strength; storage of strain energy; abundant
elastic
thin; when pulled taut, have sharp angles; can also be squiggly
collagen structure
molecule - glycine, proline, hydroxyproline triple helix
fibril - bundle of triple helices
fiber - bundles of fibrils
tissue - tendon, bundles of fibers
types of collagen (and class)
type 1 - fibrils, bones, tendons
type 2 - cartilage
type 3 - reticular fibers
type 4 - nonfibrillar (basement membrane)
elastic fibers properties
- strech
- flexibility
- branched
- fenestrated sheets
ground substance component
- glycosaminoglycans (GAGs)
- proteoglycans
ground substance function
- molecular highway/parking lot
- molecular exchange
- hydrating molecles
- more = looser
- nutrient delivery
- cell movement (plasma, mast cells)
cells found in connective tissue
- fibroblasts
- macrophages
- plasma cells
- mast cells
- leukocytes
- adipocytes
fibroblast function
synthesize matrix
wound healing
fibroblast property
dense nuclei in connective tissue
large nucleus = active
fibrocyte
thin dense nucleus
macrophage
called monocyte in blood
v good at endocytosis (particle and dye)
mast cell
primary immune response
histamine
large cells - red/purple granules
plasma cell
b-lymphocyte in blood make antibodies (sometimes see golgi bc they're working so hard) large nucleus (clock face) --> heterochromatin
leukocytes
- neutrophil
- eosinophil
- lymphocyte
adipocyte types
unilocular, multilocular