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CONNECTIVE TISSUES > Connective Tissue > Flashcards

Connective Tissue Flashcards

1
Q

Charasteristic of connective tissue

A

Cell widely separated
Large amount of extracellular matrix
Connect tissue/cell/organ together
Provide support for organ body

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2
Q

Component of connective tissue

A

Extracellular matrix (fibers,ground substances :glycosaminoglycan,proteoglycan,glycoprotein)

Cells

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3
Q

Types of CT

A

Permanent

Wandering a.k.a short time

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4
Q

Permanent CT cells

A

Fibroblast(chondro,osteoblast,reticulocytes)
Adipocytes
Mass cells
Macrophages

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5
Q

List all Wandering cells

A 
Lymphocytes
Neutrophil
Eusinophil
Basophil
Monocytes
Plasma cell
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6
Q

Population of fibroblast and adipocytes

A

Mesenchymal cell(embryonic cell)

Fixed staying there forever

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7
Q

Population of macrophages and mass cell

A

Originates from haemopoitic stem cells at bone marrow
Circulate in blood vessels
Move to CT

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8
Q

Population of wandering cells

A

Haemopoitic stem cell in bone marrow

Migrate from blood into tissue in response to specific stimuli

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9
Q

Describe fibroblast

A

Ovoid,large,pale stained nucleus
Abundant cytoplasm
Spindle shaped like
Prominent nucleus

Synthesize fiber,ground substances

Produce growth factor

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10
Q

Describe macrophages

A

Oval kidney shaped nucleus
Irregular surface

Defence-phagocytosis bacteria
Immunological-process antigen from phagocyted materials and present to the lymphocytes

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11
Q

Describe macrophages

A

Oval kidney shaped nucleus

Defence-phagocytosis bacteria
Immunological-process antigen from phagocyted materials and present to the lymphocytes

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12
Q

Describe macrophages

A

Oval kidney shaped nucleus

Defence-phagocytosis bacteria
Immunological-process antigen from phagocyted materials and present to the lymphocytes

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13
Q

Describe plasma cells

A

Spherical,Clock faced appearance bcs of the hemetrochromatin clupms,eccentric
Large ovoid cell
Juxtanuclear pale area is golgi apparatus,centrioles
Derived from b lymphocytes

Function:Immunological
-synthesize antobodies by the presence of antigen presented by the macrophages

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14
Q

Describe adipocytes

A

Unilocular fat cells-white adipose tissue,signet ring appearance

Multilocular fat cells-brown adipose tissue as it have abundant of mitochondria,common in newborn

Storage of lipid,large depot for energy and heat

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15
Q

3 types of fibers

A

Collegen
Reticular
Elastic

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16
Q

3 types of ground substances

A

Proteoglycans
Glycosaminoglycan
Glycoprotein

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17
Q

Describe collagen fibers

A

Most abundant
Collagen bundles appear as wavy structure in dense CT
Polymerization of collagen I and II protein

Collagen I is the strongest,peresnt in bone,tendon,capsules of organ,dermis
Collagen II present in cartilage
Not branching
Use acidophilic stain
White appearance under microscope
18
Q

3 Basic component in CT

A

Cells
Fibres
Ground substances

19
Q

How to classify CT

A

Functional aspect

Which component is predominating

20
Q

Describe loose (areolar) CT

A 
More ground substances
Cells mostly fibroblast and macrophages
Support lining epithelium under pressure and friction
Form layers tht sheathe the blood vessel
A submucosal and subsebacous CT
21
Q

2 types of dense CT

A

Regular dense CT

Irregular dense CT

22
Q

List macrophage cells and its location

A 
Kupffer cell (liver)
Langerhans cell (stranum spinosum)
Microglial cell (nerve tissue)
Osteoclast
23
Q

Describe plasma cells

A

Large ovoid cells
Juxtonuclear pale area:golgi body,centrioles
Nuclues: clock-face appearance due to heterochromatin clumps,eccentric,spherical

Derived from B lymphocytes

Immunogical: Synthesize antibodies in reponse to antigen presented by macrophage

24
Q

Describe mass cells

A

Abundant basophilic granules containing chemical mediator

Function : Defence (secretion of chemical mediator in response to allergic reaction)

25
Q

Describe reticular fibers

A

Collagen II fibrils
Common in hemopoitic & lymphatic tissue
Fibrils are thin,branching,extensive network
Agyrophilic:stain black with silver salt stain

26
Q

What is reticular cells

A

A type of fibrioblast

27
Q

Describe elastic fibres

A

Collagen III fibrils
Macroscopially yellowish
Thinner than collagen fibres&arranged in branching pattern

Predominates in dermis ,elastic cartilage,lung ,large artery
Major component: elastin protein produced by fibroblast,endothelial ,smooth muscle,airway epithelial cells

Allow tissue to strech&distension

Poorly stained with eiosin in H&E ,appear refractive

28
Q

Special dye for elastic fibres

A

Orcein/resorcin-fuschin,it stainelastic fibres selectively

29
Q

Describe glycosaminoglycans(GAG)

A

A polysaccharides formed by chain of disaccharide units

30
Q

Describe proteoglycans

A

80%-90% GAG and bound to a protein core(10-20%)

31
Q

Describe Glycoprotein

A

Multiadhesive glycoproteins

Function: interaction between cells,adhesion of cells to substrate

32
Q

Function of CT

A 
Connect&bind cells, tissues,organs
Defence&protection
Structural support of organ&body
Energy reservoir & heat production
Medium for exhange nutrient&metabolites
33
Q

List specialized CT

A 
Cartilage
Bone
Adipose tissue
Blood
Hemopoitic&lymphatic tissue
34
Q

What are embryonic CT

A

Mesenchyme

Mucous CT

35
Q

Describe dense CT

A

Collagen fibers&few cells predominate

Less flexible&more resistant to stres

36
Q

Describe dense regular CT

A

Collagen bundles arranged in regular pattern
Great resistance to stress in longitudinal direction
E.g : tendon,ligament

37
Q

Describe regular dense CT

A

Collagen bundles irregularly arranged
Great resistance to stress in ALL DIRECTION
E.g : dermis

37
Q

Describe regular dense CT

A

Collagen bundles irregularly arranged
Great resistance to stress in ALL DIRECTION
E.g : dermis

38
Q

Describe regular dense CT

A

Collagen bundles irregularly arranged
Great resistance to stress in ALL DIRECTION
E.g : dermis

39
Q

Describe brown adipose tissue

A

Produce more heat compare to white adipose tissue

Multilocular

40
Q

Describe white adipose tissue

A

Signet ring appearance

Unilocular

41
Q

Describe mesencyhme

A

An embryological CT
Found in embryo
Abundance of thick ground substances

Reticular(collagen) fibers: very fine&sparse

Mesenchymal cells:spindle shaped,small,uniform cells with multiple processes

CONNECTIVE TISSUES (1 decks)

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