Congenital Hypothyroidism

Question 1

Types of congenital hypothyroidism

Answer 1

Dysgenesis - underdeveloped thyroid gland.
Dysormonogenesis - fully developed gland which does not produce enough hormone

Question 2

Presentation of congenital hypothyroidism

Answer 2

Prolonged jaundice, poor feeding, constipation, increased sleeping, reduced activity, slow growth and development

Question 3

Diagnosis of congenital hypothyroidism

Answer 3

newborn blood spot screening test

Question 4

Causes of acquired hypothyroidism

Answer 4

Autoimmune thyroiditis (Hashimoto’s)

Question 5

Symptoms of acquired hypothyroidism

Answer 5

Fatigue, low energy, poor growth, weight gain, poor school performance, constipation, dry skin, hair loss

Question 6

Management of hypothyroidism

Answer 6

Levothyroxine orally once daily and doses titrated based on thyroid function tests and symptoms

Question 7

Diagnosis and tests in hypothyroidism

Answer 7

TFTs, thyroid US, thyroid antibodies (anti-TPO)