Congenital and Acquired Immunodeficiencies Flashcards
What is the name of the cancer of the epithelium?
carcinoma
What is the name of the cancer of the connective tissue?
sarcoma
What is the name of the cancer of the lymphoid system?
lymphoma
What is the name of the cancer of the blood?
leukemia
What are oncogenes?
Gene sequences that encourage cancer growth and proliferation
What are tumor suppressor genes?
Genes that discourage/inhibit cell growth and proliferation
What is immunosurveillance?
The ability of the immune cells to detect tumor cells
What is immunogenicity?
The ability of the immune cells to generate an immune response
How can immunoediting happen in 3 sequential phases?
- Elimination - immuno-surveillance to detect + destroy
- Equilibrium - immune system controls net growth
- Escape -
What are cytokines associated with?
Strong anticancer responses
T helper cells 1 and cytotoxic T cell responses
How do monoclonal antibodies work?
bind to growth receptors and interfere with signalling pathways