Confusion Flashcards

1
Q

Components of Hx to diagnose cognitive impairment

A
  • Onset (when + how rapid)
  • Course ( fluctuating/progressive decline)
  • Associated features (other illness, functional loss e.g. loss of mobility/reduced self care/new incontinence
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2
Q

Key features of delirium

A
  • Disturbed consciousness (hypo/hyper active or mixed)
  • Change in cognition (memory/perception/language/hallucinations)
  • Acute onset or fluctuant
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3
Q

Other features of delirium

A
  • Disturbance of sleep wake cycle
  • Disturbed psychomotor behaviour
  • Emotional disturbance
  • Delusions
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4
Q

How to diagnose delirium

A

4 AT (questionnaire)

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5
Q

A 4AT score of 4 above, 1-3 and 0 mean what

A
  • 4 and above = Possible delirium +/- cognitive impairment
  • 1-3 = Possible cognitive impairment
  • 0 = Delirium or severe cognitive impairment unlikely
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6
Q

When is a 4AT score essentially useless

A

When unable to comment on acute change or fluctuating course of alertness or cognition
As delirium may be present in that case even if 4AT score = 0

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7
Q

Management of delirium

A

-Stop bad drugs
Anticholinergics
Sedatives
-Drug treatment is usually not required, unless a danger to themselves or others or distress which can not be settled in another way

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8
Q

What drug can be used to treat delirium

A
  • Quetiapine orally 12.5mg

- Start low and go slow

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9
Q

Non-pharmacological treatment of delirium

A
  • Re-orientate + reassure patient (use friends/family)
  • Encourage early mobility + self care
  • Correction of sensory impairment
  • Normalise sleep-wake cycle
  • Avoid catheters + venflons
  • Ensure continuity of care (avoid frequent ward/room transfers)
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10
Q

5 types of dementia

A
  • Alzheimer’s
  • Vascular dementia
  • Mixed Alzheimer’s/vascular
  • Lewy body dementia
  • Reversible causes
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11
Q

Describe Alzheimer’s

A
  • Slow, insidious onset
  • Loss of recent memory first
  • Progressive functional decline
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12
Q

Risk factors for Alzheimer’s

A
  • AGE
  • Vascular risk factors
  • Genetics
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13
Q

Describe vascular dementia

A
  • Step-wise deterioration
  • Executive dysfunction may predominate
  • Associated with gait problems ofter
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14
Q

Risk factors for vascular dementia

A
  • Type 2 DM
  • AF
  • IHD
  • PVD
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15
Q

Describe Lewy body dementia

A
  • Link with Parkinson’s disease (2/3 will have movement problems)
  • Often very fluctuant
  • Hallucinations and falls common

Probably underdiagnosed

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16
Q

Describe fronto-temporal dementia

A
  • Onset often at earlier age
  • Early symptoms different from other types of dementia
  • Behavioural change
  • Language difficulties
  • Memory early on often not affected
  • Usually lack insight into difficulties
17
Q

How to diagnose dementia

A

Min-Mental State Exam (MMSE)

Not only means + Remember Hx is key

18
Q

Non-pharmacological management of dementia

A
  • Support for patient + carers
  • Cognitive stimulation
  • Music/light therapy
  • Reality orientation vs validation therapy
  • Environmental design
19
Q

Pharmacological management of dementia

A

Cholinesterase inhibitors (mainly used in Alzheimer’s)

  • Mixed dementia = Galantamine
  • Lewy body = Rivastigmine
20
Q

Reversible causes of dementia

A
  • Hypothyroidism
  • B12 deficiency
  • Hypercalcaemia
  • Intra cerebral bleeds/tumours
  • Normal pressure hydrocephalus
  • DEPRESSION