Conditions of the Head and Neck Flashcards
What are the risk factors for laryngeal cancer?
Tobacco use, alcohol use, HPV infection, more common in males
What is the most common type of laryngeal cancer?
Squamous cell carcinoma
What are the classic symptoms associated with laryngeal cancer?
Hoarseness for longer than 14 days, dyspnea, dysphagia, persistent cough or sore throat
How us laryngeal cancer diagnosed?
Biopsy during laryngoscopy
Given the symptom of chronic hoarseness, what would be in the ddx fro laryngeal cancer?
Laryngitis, vocal cord polyps, vocal cord nodules, GERD, TB or fungal infections of the larynx, thyroid disorders
What is the most common cause of oral cancer?
Squamous cell carcinoma associated with tobacco and alcohol use
Where are the oral cancers most commonly found?
Lip or lateral part of the tongue
What disease is associated with gingival hyperplasia?
Acute myeloblastic leukemia (AML)
What else can cause gingival hyperlasia?
Drug induced: Usually phenytoin, Cyclosporine, Nifedipine and Amlodipine
Does gingival hyperplasia go away with treatment of AML or discontinuation of the offending drugs?
Yes, it will regress
What people are most susceptible to clinically significant CMV infections?
Immunocompromised
Patients on immunosuppresive drugs
What are the common signs and symptoms of CMV?
Acute febrile illness: fever, fatigue, LAO
Hepatitis
Atypical lymphocytosis
Rash
Heptosplenomegaly
What are some other clinical findings CMV?
Retinitis: blurred vision, progressive blindness
Esophagitis: Pain, dysphagia, ulcers
Colitis: fever, diarrhea, abdominal pain, weight loss
How is CMV diagnosed?
Immunofluorescence: Direct demonstration of CMV in body fluids or tissues
PCR
Serologic testing
What drug has been used to treat CMV infection?
Acyclovir, newer generation are more commonly used now: Valacylovir, Ganciclovir
What is the hallmark presentation of diphtheria?
Gray to black fibrous coating on the posterior oropharynx, which can lead to airway obstruction
How is diphtheria spread?
Respiratory Droplets
What is a possible complication of severe acute OM?
Mastoiditis
What bacterial infection usually causes mastoiditis?
Strep pneumoniae, Strep pyogens, Haemophilius
What are the signs and symptoms of mastoiditis?
1) Usually associated with OM
2) Otalgia, *otorrhea with possible perforation of the TM
3) *Swelling and pain over mastoid process
4) Fever, may be high and unrelenting
5) External ear displacement
6) Progressive hearing loss
7) *Retroauricular swelling with protruding ear
How is mastoiditis usually diagnosed?
CT scan, culture discharge
What are the signs and symptoms of infectious mononucleosis?
Fatigue
Fever
Pharyngitis
Cervical LAO
Myalgia
What organ is enlarged in 50% of mono cases?
The spleen
How is infectious mononucleosis diagnosed?
1) Presence of atypical lymphocytes ( Downy cells) on a CBC
2) Positive Heterophile antibody (Monospot) test
3) (+) EBV specific antibodies: VCA IgM, VCA IgG, EB-NA antibodies
What would be in the DDx for mononucleosis?
CMV
Group A Beta hemolytic step (pharyngitis)
Adenovirus
Toxoplasmosis
Viral Hepatitis
HIV
Leukemia
How is mononucleosis transmitted?
1) Contact with oral secretions
2) Blood transfusion
At what time do antibodies for infectious mononucleosis appear in the serum?
6-10 days post infection
What might make you suspicious that your patient has acute closed angle glaucoma?
Periorbital pain with ipsilateral headache and vision changes changes
Closed - ocular emergency
Rare (5%)
Acute onset
Painful red eye
Very elevated IOP
Hazy cornea
Mid-dilated pupil un-reactive to light
N/V, abdominal pain
Halos around light
What is blepharitis?
Chronic inflammation leading to flaky irritated and itchy eyelids
What are the common causes of blepharitis?
Staph infection, allergies, seborrheic dermatitis, eyelash mites or lice and rosacea
What are the 3 types of conjunctivitis?
Viral
Bacterial
Allergic or Irritative
What are some common causes of bacterial conjunctivitis?
Stap, Strep, Gonorrhea, Chlamydia, Haemophilius
What are the symptoms of allergic conjunctivitis?
Velvety projection on the underside of the lid
Intense itching, watery eyes
Mucoid white stringy discharge containing eosinophils
What are the causes of viral conjunctivitis?
Adenovirus (most common), varicella zoster or herpes simplex ( most severe)
Which lasts longer, viral or bacterial conjunctivitis?
Viral tends to last longer, up to 2-4 weeks
What are the symptoms of viral conjunctivitis?
Enlarged pre-auricular lymph nodes
Clear, thin and watery discharge
Corneal injection
Usually bilateral
Photophobia
What are symptoms of bacterial conjunctivitis?
Thick, purulent, copious discharge
Usually unilateral
Swollen lids
Corneal Injection
How would you diagnose conjunctivitis?
Usually diagnosed clinically, but in cases that do not respond to empiric treatment consider culture and sensitivity of discharge
What herbs are used for conjunctivitis?
Euphrasia officinalis
Ruta graveolens
Foeniculum vulgare
Hydrastis canadensis
Verbascum Thapsus
What homeopathic remedied are indicated fro conjunctivitis in a patient with acrid, burning, tears and bland nasal discharge?
Euphrasia
What are the causes of retinal detachment?
Trauma or blow to the head or ey
Post cataract surgery
Severe myopia
What are the classic symptoms of retinal detachment?
1) Painless, dark or irregular floaters, flashes of light, blurred vision
2) Curtain or veil in field of vision
3) Loss of visual fields
What is the difference between vitreous and retinal detachment?
Vitreous detachment rarely threaten vision
What are vitreous detachments commonly called?
Floaters
What are the common signs and symptoms of keratitis?
Eye redness
Eye pain
Excessive tearing or discharge
Blurred or decreased vision
Photophobia
Condition in which the eye’s cornea, the clear dome on the front surface of the eye, becomes inflamed
What are some causes of keratitis?
Corneal Injury, contaminated contact, lenses (gram-negative bacteria), Herpes virus, contaminated water
Viral, Bacterial, funga, Amoebic, Parasitic, Enviromental
What are common signs and symptoms of optic neuritis?
Inflammation of the optic nerve; occurs in individuals younger than 50 years old
Eye pain worsened by eye movement
Loss of Color vision
Flashing lights
Vision loss may be permanent
What conditions predispose to optic neuritis?
Multiple sclerosis ( most common), SLE, Sarcoidosis, Lyme Disease
What are the risk factors for developing orbital cellulitis?
Orbital cellulitis is an infection of the soft tissues of the orbit posterior to the orbital septum
History of sinusitis, trauma or dental infections
What are the symptoms of orbital cellulitis?
Sever eye and orbital pain with orbital erythema
Lid swelling and exopthalmos
Decreased vision
Pain on eye movements
Fever, malaise, headache
How would you approach a diagnosis orbital cellulitis?
Send to ER
CT with contrast, culture of any purulent material present
What is a pterygium?
A non-cancerous growth of the conjunctiva; Rapidly growing fibrovascular lesion that can distort the cornea causing a decrease in vision, possibly astigmatism (Triangular shaped of epithelia tissue into cornea)
What are the hallmark symptoms of diabetic retinopathy?
Initially asymptomatic, then develops floaters, visual distortion and/or blurred vision in the setting of elevated blood glucose
What do you see on PE in a patient with diabetic retinopathy?
Flame hemorrhages, hard exudates, cotton wool spots (soft exudates)
What are the two types of diabetic retinopathy and which has a worse diagnosis?
Non-proliferative and proliferative. Proliferative with neovascularization has a worse prognosis.
What herb is indicated for diabetic retinopathy?
Vaccinium Myrtillus