Conditions Of GIT- Medicinal Chemistry Of Drugs Flashcards

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1
Q

Mechanism of Action of PPI

A

Irreversibly Inhibit the enzyme complex proton pump

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2
Q

Indications of PPI

A

Ulcers caused by nsaids

Used in combo with antibacterials for H pylori ulcers

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3
Q

4 clinical PPIS

A

Omeprazole
Lansoprazole
Pantoprazole
Rabeprazole

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4
Q

What is the skeleton / structure of PPIs

A

Pyridinyl methylsulfinyl benzamidazole skeleton

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