Conditions Of GIT- Medicinal Chemistry Of Drugs Flashcards
1
Q
Mechanism of Action of PPI
A
Irreversibly Inhibit the enzyme complex proton pump
2
Q
Indications of PPI
A
Ulcers caused by nsaids
Used in combo with antibacterials for H pylori ulcers
3
Q
4 clinical PPIS
A
Omeprazole
Lansoprazole
Pantoprazole
Rabeprazole
4
Q
What is the skeleton / structure of PPIs
A
Pyridinyl methylsulfinyl benzamidazole skeleton