Conditions Flashcards

1
Q

Cardiovascular drugs pre-op

A

Beta-blockers / alpha 2 agonists - continue
ACEI/ARB/diuretics; w/h morning dose
Statins; continue

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2
Q

Blood thinners pre-op

A

Warfarin; w/h 5 days
Xarelto; 48hrs
Apixaban; 48hrs
Aspirin; most continued, but if need - stop 5-7/7 prior
Clopidogrel; w/h 5-7/7
NSAIDS; 7-10/7 prior

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3
Q

Pre-op warfarin mx

A

Check INR 5-7/7 prior to surgery
INR 1.5-1.9; stop 3-4 days prior
INR 2-3; stop 5 days prior
INR >3; stop at least 5 days
Bridge; clexane 1.5mg/kg subcut (1mg/kg if CrCL <30)

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4
Q

Imaging of breast mass

A

<35yo; USS
- do mammogram if suspicious clinical findings, USS indeterminant/suspicious, or if USS not consistent with clinical exam findings
>=35yo; USS + mammogram

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5
Q

Bariatric surgery post-op checklist

A

Monitor weight and complications at each visit
Adherence to diet/exercise
Medication; avoid NSAID, adjust antiHTN/diabetic meds
Supplement
- Iron, folic acid, thiamine, B12
- Citrated calcium - elemental Ca 1200mg/day
Bloods
- FBC, U+E, LFT, uric acid, glucose, lipids every 6/12
- VD, PTH, Ca, albumin, PHo, B12, folate, iron annually

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6
Q

Carotid artery stenosis mx

A

Antiplatelet
Statin
Smoking cessation
BP control
screen DM
>80% stenosis -> non urgent vascular surgery review
<80%: medical mx + annual USS

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7
Q

Risk factors AAA

A

> 65yo
Peripheral atherosclerotic disease
Smoking
COPD
Marfan
Ehler’s-Danlos syndrome
HTN
FDR
Cholesterol

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8
Q

Indication to screen for AAA

A

Male >65yo and smoking
>65yo and FDR
Known popliteal/thoracic aortic aneurysm

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9
Q

Venous leg ulcer features

A

Haemosiderin
Lower third of leg
Shallow poorly defined edges
Granulating/sloughy base

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10
Q

Venous leg ulcer mx

A

Cleaning/debridement
Compression 30-40mmHg
Nutrition; omega 3 fatty acids, vitamin C, zinc
Leg elevation
Exercise
Weight loss
Skin care for dermatitis; paraffin emollient , steroid
Early referral to vascular surgeon

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11
Q

Superficial thrombophlebitis mx

A

If IVC complication; topical or oral NSAID
Consider anticoagulation if involves thigh veins
- Clexane 40mg 6/52
Elevation
Compression
Warm
Review in 7-10 days to ensure resolution

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12
Q

Mx of DVT

A

Exercise
Compression
Cease OCP
Anticoagulation
- Xarelto 15mg BD 3/52 -> 20mg daily
- Apixaban 10mg BD 1/52 -> 5mg BD
- Clexane 1.5mg/kg subcut
PICC related VTE; elevation, NSAID, anticoag 3/12, remove PICC if non-functional
USS surveillance as alternative if high bleeding risk
- 2-3 x USS over 2 weeks to assess progression

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13
Q

Duration of anticoagulation DVT

A

Distal DVT
- Provoked; 6/52
- Unprovoked; 3/12
Proximal
- Provoked; 3/12
- Unprovoked; 6/12

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14
Q

Examination of foot with ulcer

A

Assess for infection; discharge, smell
Hair loss / skin trophic changes
Peripheral pulses
ABPI (<0.9 abnormal)
Sensation
Reflex
Joint deformity
Gait
Footwear

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15
Q

Wound dressings

A

Hydrogel (Aquaclear); dry wounds with necrotic tissue
Hydrocolloid (Duoderm): chronic wounds with mild-moderate exudate
Foam (Allevyn): granulating wounds, mild-moderate exudate, non-infective
Cadexomer iodine (Iodosorb): wounds with malodorous exudate
Alginate (Algisite): heavy exudate

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16
Q

Steroids ADR

A

Gastric irritation
Weight gain
Glucose intolerance
Cushinoid appearance
Osteoporosis
HTN
Insomnia
Psychosis
Hypoadrenalism

17
Q

Risk factors of NSAID induced UGIB

A

Age
Hx UGIB
Hx peptic ulcer
H pylori
Anticoag/antiplatelets/SSRI
Smoking

18
Q

Antipsychotics ADR

A

Cognitive decline
Somnolence
EPSE
Oedema
Metabolic syndrome
CVA
Falls

19
Q

Causes of anovulation

A

Hypothalamic amenorrhoea
HPRL
Pituitary disease
PCOS
Congenital adrenal hyperplasia
Premature ovarian insufficiency

20
Q

Causes of male infertility

A

Hypogonadotrophic hypogonadism
HPRL
Varicocoele
Cryptorchidism
Testicular cancer
Radiation
Klinefelter syndrome
Anti-sperm Abs
Retrograde ejaculation
Congenital bilateral absence of vas deferens

21
Q

Incidence

A

Number of new cases of disease in defined population within specified period of time

22
Q

Prevalence

A

Total number of individuals with disease at a particular time in a population

23
Q

Case control study

A

Compares pt with disease/outcome vs patients without disease/outcome - looks retrospectively to see any relationship between exposed risk factor

24
Q

Specificity

A

= true -ve / (true -ve + false +ve)
Highly specific test rules IN disease

25
Q

Odds ratio

A

OR = comparative number of outcomes in exposed patients vs unexposed patients
OR > 1 indicates exposure likely is related to the outcome

26
Q

Absolute risk

A

number of outcomes / number of people in the group
- ARC - AR events in control group
- ART; AR events in treatment group
ARR (absolute risk reduction) = ARC - ART
Relative risk = ART / ARC
Number needed to treat = 1/ ARR