Comquest Questions Flashcards
What is the most important goal when designing a randomized controlled clinical trial?
Reproducibility
What is the most likely route of transmission of hepatitis C virus?
IV Drug Use
Acute pericarditis, thrombocytopenia, leukopenia, and petechiae…
Systemic Lupus Erythematosus
2 week old female with failure to thrive. Weak suckling from birth. Patient has muscle atrophy, decreased muscle tone and areflexia. Electromyogram shows muscle fibrillation. Most likely Dx?
Spinal Muscular Atrophy. AR.
What are the elements of informed consent?
- Diagnosis
- Nature of intervention
- Risks and benefits of intervention and alternatives
- Assessment of patient understanding
- Consent from patient for intervention
What is treatment of scoliosis with a Cobb angle of 20-45 degrees?
5-15?
50-75?
5-15: OMT and PT
20-45: Orthotics, PT and OMT
50-75: Surgical Intervention
>50 = Respiratory Compromise >75 = Cardiovascular Compromise
Empiric Tx for Necrotizing Fasciitis?
Meropenem
Triad of unilateral flank pain, hematuria, and a palpable abdominal mass. Dx and associated findings?
Renal Cell Carcinoma. Associated with Polycythemia and/or Hypercalcemia.
DMARD resulting in skin rashes, stomatitis, cholestatic jaundice, nephrotoxicity and bone marrow suppression?
Gold sodium thiomalate. (Old treatment rarely used now)
Icosahedral flavivirus with positive linear, single-stranded RNA. Transmitted by mosquitoes. Can cause encephalitis, severe muscle weakness, and flaccid paralysis.
West Nile Virus
Tranylcypromine, selegiline, phenelzine, isocarboxazid are all examples of what class of drug?
MAOIs
Intellectual disability, long face, large ears. Dx and chromosomal findings?
Fragile X Syndrome. CGG repeats on X Chromosome.
What is the MOA of Lactulose and what is it used to treat?
Lactulose works by acidifying colonic contents, effectively sequestering ammonia into ammonium, which is excreted. It is used to treat hepatic encephalopathy.
How do you diagnose Multiple Myeloma?
Serum and urine protein electrophoresis.
AIDS patient, AMS, obtunded, high temp, high protein CSF, low glucose CSF, what stain to dx? What is Dx?
Cryptococcus neoformans. India Ink.
Crystals that are yellow when parallel to the polarizer and blue when perpendicular to the plarizer (negatively birefringent).
Monosodium Urate Crystals. Gouty Arthritis.
What do the following thalamic nuclei relay?
Lateral Geniculate Nucleus Medial Geniculate Nucleus VPL Nucleus VPM Nucleus Pulvinar Nucleus
LGN: Vision
MGN: Hearing
VPL: Somatosensory from body to Sensory Homunculus
VPM: Somatosensory from face to Sensory Homunculus
Pulvinar Nucleus: Plays role in integrating attention from somatosensory inputs. Can produce hemispatial neglect and attention deficits if lesioned.
Name the artery affected:
Lower Extremity Paraplegia, Incontinence, Motor Aphagia, Personality Changes.
Anterior Cerebral Artery
Name the artery affected:
Hemiplegia affecting face and arm, homonymous hemianopsia, Broca’s aphagia.
Middle Cerebral Artery
Name the artery affected:
Homonymous hemianopsia w/ sparing of the macula. Unable to recognize people (prosopagnosia).
Posterior Cerebral Artery
Why do you use physostigmine for the treatment of anticholinergic OD?
Physostigmine crosses the BBB, making it more centrally acting on the brain.
Initial Tx of Acute Rheumatic Fever?
Penicillin
Alteration in Apolipoprotein C2 that leads to elevated TAGs and Cholesterol?
Familial Hyperlipidemia Type 1
Triad of hypotension, JVD, and distant heart sounds w/ pulsus paradoxus (decrease in Systolic BP >12 mmHg upon inspiration)?
Beck’s Triad of Cardiac Tamponade
