Compression Neuropathy Flashcards
Neuropathy
functional or pathologic changes in the peripheral nervous system
Compression neuropathy
-process whereby a nerve becomes entrapped as it passes through a narrow tunnel or passage
Pathological changes that occur with neuropathy include
- microvascular compression–>ischemia
- thickened epineurium
- myelin thinning distortion
- microtubule closure
- axonal degeneration
Etiology of Nerve Entrapment
- increased muscle mass by repetitive activity
- space occupying lesions (cysts or tumors)
- inflammation of surrounding tissues leads to venous congestion in epineurial and perineurial vascular plexuses–>endoneurial edema–>nerve anoxia
- Post traumatic conditions (hematoma, fracture, or compression by equipment)
- systemic causes–pregnancy, hypothyroidism or diabetes, etc.
Neurapraxia
- least severe nerve injury
- involves focal damage of myelin fibers around axon, but the connective tissue sheath remains intact
- limited course (days to weeks0
Axonotmesis
- injury to the axon itself
- regneration is possible, but prolonged (months) without full recovery
Neurotmesis
-complete disruption of the axon with little likelihood of recovery
Conservative measures for compression neuropathy include
- modification of activity, use of antiinflammatories, splinting, and/or injections
- PT, OMM, pain management
- should be pursued for 3-6 months (except with cubital tunnel syndrome)
- surgical release is considered when nonoperative management fails
Cervical Nerve Root Compression
- usually caused secondary to cervical disc disease (i.e. disc bulging or herniation)
- most commonly the disc ruptures posterior-laterally using compression of the nerve root as it exits the intervertebral foramen
- causes radiculopathy–pain caused by compression of the spinal nerve that radiates in the distribution of the defined nerve root
C5
- deltoid, biceps motor
- sensation to lateral arm
- biceps reflex
C6
- wrist extension, elbow flexion
- sensation to radial forearm, thumb and index finger
- brachioradialis reflex
C7
- wrist flexion, elbow extension, finger extension
- sensation to middle finger
- triceps reflex
C8
finger flexion
-sensation to ulnar forearm, small finger
T1
- Finger abduction
- sensation to medial arm
Peripheral Nerves at Risk in the upper extremity
- radial nerve
- median nerve
- ulnar nerve
- musculocutaneous and axillary
Radial Nerve Entrapment Sites
- High on the humerus
- radial tunnel
- at the wrist
Radial Nerve Function
- motor to triceps brachii, anconeus, wrist extensors
- sensation to majority of the dorsum of the hand (via posterior interosseous nerve)
Radial Nerve Entrapment High on the humerus
- usually secondary to a humorous fracture or compression of nerve near spinal groove
- symptoms: wrist drop, weakness of elbow flexion (brachioradialis), possible triceps involvement, +/- triceps reflex diminished, pain and numbness
- Treatment: function usually returns in 4-5 month
Radial Nerve Entrapment: Radial Tunnel Syndrom
- compression of posterior interosseous branch of the radial nerve as it passes under the supinator muscle at the Arcade of Frohse (purely motor branch)
- Supinator syndrome
- repetitive rotatory movements–>rowing, discus, racquet sports
- heavy manual labor
- symptoms: pain and tenderness 5 cm distal to lateral epicondyle
- wrist drop or pain with resisted supination
Median nerve Entrapment sites of entrapment
- ligament of Strutters
- Pronator Syndrome
- Anterior Osseous Syndrome
- Carpal Tunnel Syndrome
Median Nerve functions
- forearm flexion and pronation
- wrist flexion and radial deviation
- thumb abduction and opposition
- index and middle finger abduction and flexion