Comprehensive Flashcards
1.How would fibers conveying impulses from primary motor complex to the brainstem motor nuclei? A. Projection fibers B. Commissural fibers C. Short association fibers D. Long association fibers
A. Projection fibers
2. Which of the following sulci listed below separates the frontal from the parietal lobe? A. Central Sulcus B. Lateral Sulcus C. Parieto-occipital sulcus D. Superior sulcus
A. Central Sulcus
Lobe which could cause visual impairment when injured
- occipital lobe
. What structures are close together in the junction between the pons and medulla? A. Trigeminal and Trochlear Nerve B. Oculomotor and Optic Nerve C. Facial and Acoustic Nerve D. Optic and Opthalmic Nerve
C. Facial and Acoustic Nerve
- Which of the following gyri below is closely associated with speech?
a. precentral gyrus
b. angular gyrus
c. inferior frontal gyrus
d. superior temporal gyrus
c. inferior frontal gyrus - daw broca’s area
7. Which of the following can be seen deep of the lateral sulcus A. Temporal lobe B. Insula C. Limbic lobe D. Uncus
B. Insula
Where can you find the primary auditory complex.
a. temporal
b. occipital
c. parietal
c. parietal
9. Structure that lies below Pineal gland? A. Tegmentun B. Tectum C. Oculomotor Nerve D. Cerebral Peduncle
B. Tectum
Which of the following structures lie medial to the putamen? A. Extreme capsule B. Internal capsule C. External capsule D. Corpus callosum
B. Internal capsule
11. Which of the following is the most potent for the increase of CBF? A.Hypoxia B.Hypercarbia C.Acidosis D.Emotional Stress
C.Acidosis
11.In cases where a person is under emotional stress and hyperventilates, and the partial pressure of CO2 decreases, cerebral blood flow would: A. Decrease B. Increase C. Unchanged D. Increase only in the limbic areas
A. Decrease
Cerebral blood flow normal
Not in the choices but accdg sa ppt, 50-65 mL/100g/minute
17. Which of the following CSF-filled cavities is associated with mesencephalon? A. Lateral B. Third C. Cerebral aqueduct D. Fourth
C. Cerebral aqueduct
18. Concepts of neurotransmission can be described anatomically by the following: A. Neurons and synapses B. Neurotransmitters C. Action Potential D. All of the Above
D. All of the Above
19.The resting potential membrane of a myelinated nerve fiber is primarily affected by the concentration of which ion A.Calcium B.Chloride C.Potassium D.Sodium
D.Sodium
- Which of the following generates IPSP?
a. Something something due K channel
b. Opening of Na channel
c. Opening Ca channel
d. Opening of Cl Channel
d.Opening of Cl Channel
The faster rate of impulse transmission in myelinated nerve fibers is due to node to node transfer of action potential. This is known as:
Ans. Saltatory conduction
23. What is the basis of absolute refractory period? A. Closure of Na+ activation gates B. Closure of Na+ inactivation gates C. Closure of K+ activation gates D. Closure of K+ inactivation gates
B. Closure of Na+ inactivation gates
A neuron which summated postsynaptic potential is excitatory but has not reached a level high enough to obtain threshold to produce firing by a postsynaptic neuron
Facilitated neuron
- Temporal summation thru:
A. Summation of succesive discharge from single presynaptic terminal of neuron
B. Summation of simultaneous potential from multiple active postsynaptic
C. Both a&b
D. Nota
A. Summation of succesive discharge from single presynaptic terminal of neuron
26) Which of the following is the basis for absolute refractory period?
A) Closure of calcium activated gate
B) Closure of calcium non
A) Closure of calcium activated gate
27. Sodium channels can be blocked by which of the following when it is applied to the outside of the cell membrane where sodium channel gates ang located A. EDTA B. Ouabain C. Tetraethylammoniun ion D. Tetrodoxin
D. Tetrodoxin
28.Which of the following statements is true regarding the generation of Action Potential?
A. When dendrite reach threshold, generate Action Potential
B. Action Potential is initiated at axon hillock
C. Voltage Gated Na+ channels are bla bla near Nodes of Ranvier
C. Electrotonic conduction run its course into completion
B. Action Potential is initiated at axon hillock
29.Cavities from the myencephalon
answer: fourth ventricle
- Which of the following cavities come from the diencephalon?
Answer: 3rd ventricle
Lateral: telencephalon
Aqueduct: mesencephalon
4th: Rhombocephalon
31. In which structure does CSF absorption occur? A. Lumbar cistern B. Spinal nerve rootlets C. Choroid plexus D. Arachnoid granulations
D. Arachnoid granulations
32. Which of the following dura reflected is located within the superior longitudinal fissure? A. Tentorium cerebelli B. Falx cerebri C. Falx cerebelli D. Diaphragma sellae
B. Falx cerebri
33. Which dural reflection separates the pituitary gland from the hypothalamus? A. tentorium cerebelli B. falx cerebri C. falx cerebelli D. diaphragm sella
D. diaphragm sella
34. Which of the following structure is derived from ectoderm Notochord Somites D A
ambot
- The closing of the neural groove and the formation of neural tube happen at what embryological development stage?
a. 20 day stage
b. morula
c. 33 somite stage
d. Blastula
a. 20 day stage
- Synapses can regulate signal transmission because:
A. It can direct the spread of signals
B. Has molecular machinery that controls transmission
C. It can refine and process transmission
D. All of the above
D. All of the above
37. Neurotransmitter released in the synaptic cleft is triggered by A. Na+ B. K+ C. Cl- D. Ca2+
D. Ca2+
- Which is false.
A. Electrical synapses are dedicated in transferring of information
B. Synaptic transmission is fast efficient dynamic
C. Synapses share properties with intercellular junctions they only vary because they transmit info and are plastic
D. Synapses exhibit various properties by pre and post synaptic neuron
c sguro
41. Depolarization of the post synaptic neuron is brought about by the: (Deleted #) A. Influx of Na+ B. Efflux of Na+ C. Influx of K+ D. Efflux of K+
A. Influx of Na+
- What produces Myelin Sheaths in the CNS-
Answer: Oligodendrocytes
42.What cell supports the CNS?
Answer:Astrocytes
- cells that lines the ventricles.
Answer:Ependymal
Gaps between myelin sheath with high sodium concentration
Nodes of ranvier-
- Nucleus
Answer:genetic center of neuron
- Pseudo Unipolar
unipolar neuron. one branch then branch to two. one to cns and other to pns
- Bipolar
ambot
49.Pyramidal
ambot
50. Which of the following is the second messenger in neuronal sensory transmission A. calcium B. Potassium C. Sodium D. Chloride
A. calcium
52. A neuron is facilitated if the action potential (not sure) becomes A. Above threshold B. More positive, subthreshold C. More negative, subthreshold D. None of the above
C. More negative, subthreshold
- Why is conduction faster in myelinated fibers?
A. Myelin is rich in sodium and potassium channels
B. Myelin is rich in potassium and calcium channels
C. Myelin is rich in sodium and calcium channels
D. Myelin prevents current leakage
D. Myelin prevents current leakage
- What would be the effect of hypokalemia on the resting membrane potential of the neuron?
A.RMP would be less negative, neuronal activity is more excitable
B.RMP less negative, neuronal activity is less excitable
C.RMP more negative, neuronal activity is more excitable
D.RMP more negative, neuronal activity is less excitable
D.RMP more negative, neuronal activity is less excitable
55. Conformation of Na ion channel with least energy state during resting membrane potential A.Closed B.Open C.Activated D.Inactivated?
A.Closed
- Which is true for neurotransmitters?
A. Small molecule neurotransmitters are synthesized in rough endoplasmic reticulum
B. Peptide neurotransmitters are synthesized in cytosol
C. Peptides that act as neurotransmitters can also act as hormones
D. Metabotropic neurotransmitters act on voltage gated ion channels
C. Peptides that act as neurotransmitters can also act as hormones
- True of Grand Post Synaptic Potential except:
a. It is a combination of signals received from multiple synapses
b. It is positively influenced by inhibition
c. It results from a combination Excitatory and inhibitory synapses
d. It determines rate of firing
c.It results from a combination Excitatory and inhibitory synapse
- Regulation of signal transduction can be done through receptor regulation through the ff
A. Desensitization (numb to stimulus)
B. Degradation or recycling receptors (sequestration of receptors that are constantly stimulated)
C. Down regulation of receptors (enhanced degradation of receptor or receptor mRNA & decreased transcription of mRNA)
D. All of the above
D. All of the above
58. Neurotransmitters from Hypothalamus stored at A.Small vesicles B.Neural vesicles C.Large dense vesicles D.No storage
B.Neural vesicles
- The process of memory requires changes in the neurons that would persist for a period of time. These changes can be brought about by G protein activation which are as follows, except:
a. hydrolysis of ATP and GTP to form cAMP and cGMP.
b. Activation of one or more neuronal enzymes
c. Activation of gene transcription
d. Inactivation of inhibitory ion channels.
d. Inactivation of inhibitory ion channels.
- The difference between the length of the spinal cord?
A. Difference of rate of growth of canal and cord.
B. Shortening of the spinal cord
C. Cell death on the lower portion of the spinal cord
D. Unknown explanation
A. Difference of rate of growth of canal and cord.
- The transition fibers from the medulla to the spinal cord is marked by:
A. The appearance of decussating fibers from the corticospinal tract
B. The disappearance of butterfly shape gray matter
C. Transverse fibers in front of the brain stem
D. Substancia gellatinosa is replaced by the hypoglossal nerve
A. The appearance of decussating fibers from the corticospinal tract
- One of the manifestations can be seen in both lower and upper motor nucleus lesion
A. Spasticity B. Hyperflexia
C. Paralysis D. Hypotonia
C. Paralysis
5. Lesions of the corticospinal tract: A. Toe response is flexor B. Superficial abdominal reflex is preserved C. Cremasteric reflex is preserved D. Loss of voluntary movement
C. Cremasteric reflex is preserved
- Based on the course of the spinothalamic tract as it ascends ln the spinal cord, a lesion in the central canal of the spinal cord at the mid thoracic region would cause?
A. Paralysis involving both lower extremeties
B. Loss of proprioception on both lower extremeties
C. Loss of pain sensation on both lower extremeties
D. Loss of deep tendon reflex on both lower extremeties
C. Loss of pain sensation on both lower extremeties
SPINOTHALAMIC TRACTS (from Carpenter’s p 373)
- ascending pathway;
- arise from cells within spinal gray matter
- fibers arise CONTRALATERALLY from Lamina I and V.
- fibers cross in the anterior white commissure and collect CONTRALATERALLY into 3 bundles:
> Anterior Spinothalamic “light touch”
> Lateral Spinothalamic pain/thermal sense
> Spinocervical tracts
- Which of the following is true about the tectospinal tract?
A. Fibers arise from the are involved in vestibulospinal tract
B. Fibers arise from the superior colliculus
C. Fibers are involved in head righting reflex in primates
D. Projects primarily in the cervical and thoracic part of the spinal cord.
B. Fibers arise from the superior colliculus
TECTOSPINAL TRACT (from Carpenter’s p 389)
- arise from neurons in deeper layers of superior colliculus, cross in dorsal tegmental decussation, descend near median raphe anterior to MLF
- majority of fibers terminate in upper 4 cervical segments in Lamina VI(some parts), VII, VIII
- none of these fibers terminate directly in alpha motor neurons
- reflex postural movements in response to visual and auditory stimuli
- Which of the following statements is found in the spinothalamic tract?
A. The neurons that give rise to ascending fibers are found in the dorsal root of ganglion
B. Fibers terminate in fasciculus gracilis and cuneatus
C. Fibers conduct proprioceptive impulses from periphery
D. fibers from first neuron cross the midline
A. The neurons that give rise to ascending fibers are found in the dorsal root of ganglion